Diabetes -- Table of Contents (May 2003, 52 [5])

Perspectives in Diabetes:

Guidelines for Intervention Trials in Subjects With Newly Diagnosed Type 1 Diabetes: Carla J. Greenbaum and Leonard C. Harrison
Diabetes 2003 52: 1059 -1065. [Extract] [Full Text] [PDF]

Metabolism and Signal Transduction:

5-Amino-Imidazole Carboxamide Riboside Increases Glucose Transport and Cell-Surface GLUT4 Content in Skeletal Muscle From Subjects With Type 2 Diabetes: Heikki A. Koistinen, Dana Galuska, Alexander V. Chibalin, Jing Yang, Juleen R. Zierath, Geoffrey D. Holman, and Harriet Wallberg-Henriksson
Diabetes 2003 52: 1066 -1072. [Abstract] [Full Text] [PDF]

Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells: Roles of MAPK^erk and MAPK^p38: Wo-Shing Au, Hsiang-fu Kung, and Marie C. Lin
Diabetes 2003 52: 1073 -1080. [Abstract] [Full Text] [PDF]

Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin: Coen H. Wiegman, Robert H.J. Bandsma, Margriet Ouwens, Fjodor H. van der Sluijs, Rick Havinga, Theo Boer, Dirk-Jan Reijngoud, Johannes A. Romijn, and Folkert Kuipers
Diabetes 2003 52: 1081 -1089. [Abstract] [Full Text] [PDF]

A Role for Suppressed Thermogenesis Favoring Catch-Up Fat in the Pathophysiology of Catch-Up Growth: Raffaella Crescenzo, Sonia Samec, Vladan Antic, Francoise Rohner-Jeanrenaud, Josiane Seydoux, Jean-Pierre Montani, and Abdul G. Dulloo
Diabetes 2003 52: 1090 -1097. [Abstract] [Full Text] [PDF]

Restoration of Euglycemia and Normal Acute Insulin Response to Glucose in Obese Subjects With Type 2 Diabetes Following Bariatric Surgery: Eftihia V. Polyzogopoulou, Fotios Kalfarentzos, Apostolos G. Vagenakis, and Theodore K. Alexandrides
Diabetes 2003 52: 1098 -1103. [Abstract] [Full Text] [PDF]

Obesity Studies:

Adipose Tissue Is a Major Source of Interleukin-1 Receptor Antagonist: Upregulation in Obesity and Inflammation: Cristiana E. Juge-Aubry, Emmanuel Somm, Vittorio Giusti, Agnès Pernin, Rachel Chicheportiche, Chantal Verdumo, Françoise Rohner-Jeanrenaud, Danielle Burger, Jean-Michel Dayer, and Christoph A. Meier
Diabetes 2003 52: 1104 -1110. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

A New Murine Model of Islet Xenograft Rejection: Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages: Peter Schmidt, Henrik Krook, Akira Maeda, Olle Korsgren, and Birgitta Benda
Diabetes 2003 52: 1111 -1118. [Abstract] [Full Text] [PDF]

Adenovirus Early Region 3 Antiapoptotic 10.4K, 14.5K, and 14.7K Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice: Melissa A. Pierce, Harold D. Chapman, Cristina M. Post, Anton Svetlanov, Shimon Efrat, Marshall Horwitz, and David V. Serreze
Diabetes 2003 52: 1119 -1127. [Abstract] [Full Text] [PDF]

Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation: Polly J. Bingley, Ezio Bonifacio, and Patricia W. Mueller
Diabetes 2003 52: 1128 -1136. [Abstract] [Full Text] [PDF]

An Association of Autoantibody Status and Serum Cytokine Levels in Type 1 Diabetes: Pejman Hanifi-Moghaddam, Nanette C. Schloot, Simone Kappler, Jochen Seißler, and Hubert Kolb
Diabetes 2003 52: 1137 -1142. [Abstract] [Full Text] [PDF]

Successful Human Islet Isolation Utilizing Recombinant Collagenase: Heide Brandhorst, Daniel Brandhorst, Friederike Hesse, Dorothee Ambrosius, Mathias Brendel, Yoshiyuki Kawakami, and Reinhard G. Bretzel
Diabetes 2003 52: 1143 -1146. [Abstract] [Full Text] [PDF]

Islet Studies:

A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line: Fiona M. Gribble, Leanne Williams, Anna K. Simpson, and Frank Reimann
Diabetes 2003 52: 1147 -1154. [Abstract] [Full Text] [PDF]

Overexpression of PACAP in Transgenic Mouse Pancreatic ß-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes: Kyohei Yamamoto, Hitoshi Hashimoto, Shuhei Tomimoto, Norihito Shintani, Jun-ichi Miyazaki, Fumi Tashiro, Hiroyuki Aihara, Takao Nammo, Ming Li, Kazuya Yamagata, Jun-ichiro Miyagawa, Yuji Matsuzawa, Yuki Kawabata, Yuji Fukuyama, Kazumi Koga, Wakaba Mori, Kazuhiro Tanaka, Toshio Matsuda, and Akemichi Baba
Diabetes 2003 52: 1155 -1162. [Abstract] [Full Text] [PDF]

Analysis of Insulin-Producing Cells During In Vitro Differentiation From Feeder-Free Embryonic Stem Cells: Yusuke Moritoh, Eiji Yamato, Yumiko Yasui, Satsuki Miyazaki, and Jun-ichi Miyazaki
Diabetes 2003 52: 1163 -1168. [Abstract] [Full Text] [PDF]

Nuclear Factor ${kappa}$ B Protects Pancreatic ß-Cells From Tumor Necrosis Factor- ${alpha}$ -Mediated Apoptosis: Inik Chang, Sunshin Kim, Ja Young Kim, Namjoo Cho, Yun-Hee Kim, Hun Sik Kim, Moon-Kyu Lee, Kwang-Won Kim, and Myung-Shik Lee
Diabetes 2003 52: 1169 -1175. [Abstract] [Full Text] [PDF]

Intra-Islet Somatostatin Regulates Glucagon Release via Type 2 Somatostatin Receptors in Rats: Kenan Cejvan, David H. Coy, and Suad Efendic
Diabetes 2003 52: 1176 -1181. [Abstract] [Full Text] [PDF]

Pathophysiology:

Circulating Adiponectin Levels Are Reduced in Nonobese but Insulin-Resistant First-Degree Relatives of Type 2 Diabetic Patients: F. Pellmé, U. Smith, T. Funahashi, Y. Matsuzawa, H. Brekke, O. Wiklund, M.-R. Taskinen, and P.-A. Jansson
Diabetes 2003 52: 1182 -1186. [Abstract] [Full Text] [PDF]

Deleterious Effects of Acute Treatment With a Peroxisome Proliferator–Activated Receptor- ${gamma}$ Activator in Myocardial Ischemia and Reperfusion in Pigs: Ya Xu, Li Lu, Clifford Greyson, Jenny Lee, Michael Gen, Koichiro Kinugawa, Carlin S. Long, and Gregory G. Schwartz
Diabetes 2003 52: 1187 -1194. [Abstract] [Full Text] [PDF]

Sleep-Related Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes: Reduced Awakening From Sleep During Hypoglycemia: Salomon Banarer and Philip E. Cryer
Diabetes 2003 52: 1195 -1203. [Abstract] [Full Text] [PDF]

Complications:

A Low-Iron-Available, Polyphenol-Enriched, Carbohydrate-Restricted Diet to Slow Progression of Diabetic Nephropathy: Francesco S. Facchini and Kami L. Saylor
Diabetes 2003 52: 1204 -1209. [Abstract] [Full Text] [PDF]

NCEP-Defined Metabolic Syndrome, Diabetes, and Prevalence of Coronary Heart Disease Among NHANES III Participants Age 50 Years and Older: Charles M. Alexander, Pamela B. Landsman, Steven M. Teutsch, and Steven M. Haffner
Diabetes 2003 52: 1210 -1214. [Abstract] [Full Text] [PDF]

Plasma Prekallikrein: A Risk Marker for Hypertension and Nephropathy in Type 1 Diabetes: Ayad A. Jaffa, Ramon Durazo-Arvizu, Deyi Zheng, Daniel T. Lackland, Sujata Srikanth, W. Timothy Garvey, and Alvin H. Schmaier
Diabetes 2003 52: 1215 -1221. [Abstract] [Full Text] [PDF]

Maternal Diabetes In Vivo and High Glucose In Vitro Diminish GAPDH Activity in Rat Embryos: Parri Wentzel, Andreas Ejdesjö, and Ulf J. Eriksson
Diabetes 2003 52: 1222 -1228. [Abstract] [Full Text] [PDF]

Downregulation of Fibronectin Overexpression Reduces Basement Membrane Thickening and Vascular Lesions in Retinas of Galactose-Fed Rats: Sayon Roy, Tsuyoshi Sato, Gulabray Paryani, and Richard Kao
Diabetes 2003 52: 1229 -1234. [Abstract] [Full Text] [PDF]

Increased Expression of Ornithine Decarboxylase in Distal Tubules of Early Diabetic Rat Kidneys: Are Polyamines Paracrine Hypertrophic Factors?: Aihua Deng, Karen A. Munger, Jose M. Valdivielso, Joseph Satriano, Mark Lortie, Roland C. Blantz, and Scott C. Thomson
Diabetes 2003 52: 1235 -1239. [Abstract] [Full Text] [PDF]

Diabetic LDL Triggers Apoptosis in Vascular Endothelial Cells: Michaela Artwohl, Wolfgang F. Graier, Michael Roden, Martin Bischof, Angelika Freudenthaler, Werner Waldhäusl, and Sabina M. Baumgartner-Parzer
Diabetes 2003 52: 1240 -1247. [Abstract] [Full Text] [PDF]

A Novel Role for CD36 in VLDL-Enhanced Platelet Activation: Nicola A. Englyst, Janis M. Taube, Timothy J. Aitman, Trevor P. Baglin, and Christopher D. Byrne
Diabetes 2003 52: 1248 -1255. [Abstract] [Full Text] [PDF]

High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells: Narkunaraja Shanmugam, Marpadga A. Reddy, Mausumee Guha, and Rama Natarajan
Diabetes 2003 52: 1256 -1264. [Abstract] [Full Text] [PDF]

Genetics:

The Peroxisome Proliferator-Activated Receptor- ${gamma}$ 2 Gene Polymorphism (Pro12Ala) Beneficially Influences Insulin Resistance and Its Tracking From Childhood to Adulthood: The Bogalusa Heart Study: Shengxu Li, Wei Chen, Sathanur R. Srinivasan, Eric Boerwinkle, and Gerald S. Berenson
Diabetes 2003 52: 1265 -1269. [Abstract] [Full Text] [PDF]

Endothelial Nitric Oxide Synthase Polymorphisms Are Associated With Type 2 Diabetes and the Insulin Resistance Syndrome: Lucilla D. Monti, Cristina Barlassina, Lorena Citterio, Elena Galluccio, Carlo Berzuini, Emanuela Setola, Gianpietro Valsecchi, Pietro Lucotti, Guido Pozza, Luisa Bernardinelli, Giorgio Casari, and PierMarco Piatti
Diabetes 2003 52: 1270 -1275. [Abstract] [Full Text] [PDF] Appendix

Brief Genetics Reports:

Genetic Variation in the Small Heterodimer Partner Gene and Young-Onset Type 2 Diabetes, Obesity, and Birth Weight in U.K. Subjects: Simon M.S. Mitchell, Michael N. Weedon, Katharine R. Owen, Beverley Shields, Beverley Wilkins-Wall, Mark Walker, Mark I. McCarthy, Timothy M. Frayling, and Andrew T. Hattersley
Diabetes 2003 52: 1276 -1279. [Abstract] [Full Text] [PDF]

A Common Polymorphism in the Promoter of UCP2 Contributes to the Variation in Insulin Secretion in Glucose-Tolerant Subjects: Giorgio Sesti, Marina Cardellini, Maria Adelaide Marini, Simona Frontoni, Monica D’Adamo, Silvia Del Guerra, Davide Lauro, Pierluigi De Nicolais, Paolo Sbraccia, Stefano Del Prato, Sergio Gambardella, Massimo Federici, Piero Marchetti, and Renato Lauro
Diabetes 2003 52: 1280 -1283. [Abstract] [Full Text] [PDF]

Linkage for BMI at 3q27 Region Confirmed in an African-American Population: Amy Luke, Xiaodong Wu, Xiaofeng Zhu, Donghui Kan, Yan Su, and Richard Cooper
Diabetes 2003 52: 1284 -1287. [Abstract] [Full Text] [PDF]

Contribution of Variants in the Small Heterodimer Partner Gene to Birthweight, Adiposity, and Insulin Levels: Mutational Analysis and Association Studies in Multiple Populations: Chiao-Chien Connie Hung, I. Sadaf Farooqi, Ken Ong, Jian’an Luan, Julia M. Keogh, Marcus Pembrey, Giles S.H. Yeo, David Dunger, Nicholas J. Wareham, and Stephen O’ Rahilly
Diabetes 2003 52: 1288 -1291. [Abstract] [Full Text] [PDF] Appendix

Genetic Variation in the Human Winged Helix/Forkhead Transcription Factor Gene FOXC2 in Pima Indians: Peter Kovacs, Angela Lehn-Stefan, Michael Stumvoll, Clifton Bogardus, and Leslie J. Baier
Diabetes 2003 52: 1292 -1295. [Abstract] [Full Text] [PDF]

Association of Polymorphisms in GPR10, the Gene Encoding the Prolactin-Releasing Peptide Receptor With Blood Pressure, but not Obesity, in a U.K. Caucasian Population: Sumit Bhattacharyya, Jian’an Luan, Benjamin Challis, Catherine Schmitz, Paul Clarkson, Paul W. Franks, Rita Middelberg, Julia Keogh, I. Sadaf Farooqi, Carl Montague, John Brennand, Nicholas J. Wareham, and Stephen O’Rahilly
Diabetes 2003 52: 1296 -1299. [Abstract] [Full Text] [PDF] Appendix

Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility: Christopher J. Groves, Steven Wiltshire, Damian Smedley, Katherine R. Owen, Timothy M. Frayling, Mark Walker, Graham A. Hitman, Jonathan C. Levy, Stephen O’Rahilly, Stephan Menzel, Andrew T. Hattersley, and Mark I. McCarthy
Diabetes 2003 52: 1300 -1305. [Abstract] [Full Text] [PDF] Appendix

Errata:

Errata: Diabetes 2003 52: 1306 -1307. [Extract] [Full Text] [PDF]