Diabetes -- Table of Contents (August 2003, 52 [8])

Metabolism:

Effect of Training on Muscle Triacylglycerol and Structural Lipids: A Relation to Insulin Sensitivity?: Jørn W. Helge and Flemming Dela
Diabetes 2003 52: 1881 -1887. [Abstract] [Full Text] [PDF]

Impact of Aerobic Exercise Training on Age-Related Changes in Insulin Sensitivity and Muscle Oxidative Capacity: Kevin R. Short, Janet L. Vittone, Maureen L. Bigelow, David N. Proctor, Robert A. Rizza, Jill M. Coenen-Schimke, and K. Sreekumaran Nair
Diabetes 2003 52: 1888 -1896. [Abstract] [Full Text] [PDF]

Interaction of Insulin and Prior Exercise in Control of Hepatic Metabolism of a Glucose Load: R. Richard Pencek, Freyja James, D. Brooks Lacy, Kareem Jabbour, Phillip E. Williams, Patrick T. Fueger, and David H. Wasserman
Diabetes 2003 52: 1897 -1903. [Abstract] [Full Text] [PDF]

Signal Transduction:

Chronic Endothelin-1 Treatment Leads to Insulin Resistance In Vivo: Jason J. Wilkes, Andrea Hevener, and Jerrold Olefsky
Diabetes 2003 52: 1904 -1909. [Abstract] [Full Text] [PDF]

Insulin Resistance in Tetracycline-Repressible Munc18c Transgenic Mice: Beth A. Spurlin, Rhonda M. Thomas, Angela K. Nevins, Hyo-Jeong Kim, Yoon-Jung Kim, Hye-Lim Noh, Gerald I. Shulman, Jason K. Kim, and Debbie C. Thurmond
Diabetes 2003 52: 1910 -1917. [Abstract] [Full Text] [PDF]

A Peroxovanadium Compound Stimulates Muscle Glucose Transport as Powerfully as Insulin and Contractions Combined: Lorraine A. Nolte, Dong-Ho Han, Polly A. Hansen, Kathleen A. Hucker, and John O. Holloszy
Diabetes 2003 52: 1918 -1925. [Abstract] [Full Text] [PDF]

Activation of Protein Kinase C- ${zeta}$ by Insulin and Phosphatidylinositol-3,4,5-(PO₄)₃ Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise: Mary Beeson, Mini P. Sajan, Michelle Dizon, Dmitry Grebenev, Joaquin Gomez-Daspet, Atsushi Miura, Yoshinori Kanoh, Jennifer Powe, Gautam Bandyopadhyay, Mary L. Standaert, and Robert V. Farese
Diabetes 2003 52: 1926 -1934. [Abstract] [Full Text] [PDF]

Insulin-Stimulated Protein Kinase C ${lambda}$ / ${zeta}$ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction: Young-Bum Kim, Ko Kotani, Theodore P. Ciaraldi, Robert R. Henry, and Barbara B. Kahn
Diabetes 2003 52: 1935 -1942. [Abstract] [Full Text] [PDF]

Rosiglitazone Improves Downstream Insulin Receptor Signaling in Type 2 Diabetic Patients: Yoshinori Miyazaki, Helen He, Lawrence J. Mandarino, and Ralph A. DeFronzo
Diabetes 2003 52: 1943 -1950. [Abstract] [Full Text] [PDF]

Obesity:

Central Pro-opiomelanocortin Gene Delivery Results in Hypophagia, Reduced Visceral Adiposity, and Improved Insulin Sensitivity in Genetically Obese Zucker Rats: Gang Li, Charles V. Mobbs, and Philip J. Scarpace
Diabetes 2003 52: 1951 -1957. [Abstract] [Full Text] [PDF]

Variation in Type 2 Diabetes-Related Traits in Mouse Strains Susceptible to Diet-Induced Obesity: Martin Rossmeisl, Jong S. Rim, Robert A. Koza, and Leslie P. Kozak
Diabetes 2003 52: 1958 -1966. [Abstract] [Full Text] [PDF]

Immunology:

Blockade of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Exacerbates Type 1 Diabetes in NOD Mice: Qing-Sheng Mi, Dalam Ly, S.-E. Lamhamedi-Cherradi, Konstantin V. Salojin, Li Zhou, Marsha Grattan, Craig Meagher, Peter Zucker, Youhai H. Chen, James Nagle, Dennis Taub, and Terry L. Delovitch
Diabetes 2003 52: 1967 -1975. [Abstract] [Full Text] [PDF]

Prevention of Diabetes in NOD Mice by Administration of Dendritic Cells Deficient in Nuclear Transcription Factor- ${kappa}$ B Activity: Linlin Ma, Shiguang Qian, Xiaoyan Liang, Lianfu Wang, Jennifer E. Woodward, Nick Giannoukakis, Paul D. Robbins, Suzanne Bertera, Massimo Trucco, John J. Fung, and Lina Lu
Diabetes 2003 52: 1976 -1985. [Abstract] [Full Text] [PDF]

Islet:

Endothelial Differentiation Gene Receptors in Pancreatic Islets and INS-1 Cells: Suzanne G. Laychock, Yingrao Tian, and Shawn M. Sessanna
Diabetes 2003 52: 1986 -1993. [Abstract] [Full Text] [PDF]

Free Radicals and the Pathogenesis of Type 1 Diabetes: ß-Cell Cytokine-Mediated Free Radical Generation Via Cyclooxygenase-2: Tahereh Tabatabaie, Angelica Vasquez-Weldon, Danny R. Moore, and Yashige Kotake
Diabetes 2003 52: 1994 -1999. [Abstract] [Full Text] [PDF]

Small-Conductance Calcium-Activated K⁺ Channels Are Expressed in Pancreatic Islets and Regulate Glucose Responses: Natalia A. Tamarina, Yong Wang, Loris Mariotto, Andrey Kuznetsov, Chris Bond, John Adelman, and Louis H. Philipson
Diabetes 2003 52: 2000 -2006. [Abstract] [Full Text] [PDF]

Characterization of Endocrine Progenitor Cells and Critical Factors for Their Differentiation in Human Adult Pancreatic Cell Culture: Ru Gao, Jarkko Ustinov, Mari-Anne Pulkkinen, Karolina Lundin, Olle Korsgren, and Timo Otonkoski
Diabetes 2003 52: 2007 -2015. [Abstract] [Full Text] [PDF]

Pancreatic Precursors and Differentiated Islet Cell Types From Murine Embryonic Stem Cells: An In Vitro Model to Study Islet Differentiation: Brenda W. Kahan, Lynn M. Jacobson, Debra A. Hullett, Jaime M. Ochoada, Terry D. Oberley, Katharine M. Lang, and Jon S. Odorico
Diabetes 2003 52: 2016 -2024. [Abstract] [Full Text] [PDF]

Diabetogenic Potential of Human Pathogens Uncovered in Experimentally Permissive ß-Cells: Malin Flodström, Devin Tsai, Cody Fine, Amy Maday, and Nora Sarvetnick
Diabetes 2003 52: 2025 -2034. [Abstract] [Full Text] [PDF]

Label-Retaining Cells in the Rat Pancreas: Location and Differentiation Potential in Vitro: Bertrand Duvillié, Myriam Attali, Virginie Aiello, Eric Quemeneur, and Raphael Scharfmann
Diabetes 2003 52: 2035 -2042. [Abstract] [Full Text] [PDF]

K_ATP Channels and Pancreatic Islet Blood Flow in Anesthetized Rats: Increased Blood Flow Induced by Potassium Channel Openers: Leif Jansson, Mikael Kullin, F. Anders Karlsson, Birgitta Bodin, John Bondo Hansen, and Stellan Sandler
Diabetes 2003 52: 2043 -2048. [Abstract] [Full Text] [PDF]

Insulin Constitutively Secreted by ß-Cells Is Necessary for Glucose-Stimulated Insulin Secretion: Siddhartha Srivastava and H. Joseph Goren
Diabetes 2003 52: 2049 -2056. [Abstract] [Full Text] [PDF]

Pancreatic ß-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase: Maria Sörhede Winzell, Håkan Svensson, Sven Enerbäck, Kim Ravnskjaer, Susanne Mandrup, Victoria Esser, Peter Arner, Marie-Clotilde Alves-Guerra, Bruno Miroux, Frank Sundler, Bo Ahrén, and Cecilia Holm
Diabetes 2003 52: 2057 -2065. [Abstract] [Full Text] [PDF]

Vesicular Inhibitory Amino Acid Transporter Is Present in Glucagon-Containing Secretory Granules in ${alpha}$ TC6 Cells, Mouse Clonal ${alpha}$ -Cells, and ${alpha}$ -Cells of Islets of Langerhans: Mitsuko Hayashi, Masato Otsuka, Riyo Morimoto, Akiko Muroyama, Shunsuke Uehara, Akitsugu Yamamoto, and Yoshinori Moriyama
Diabetes 2003 52: 2066 -2074. [Abstract] [Full Text] [PDF]

Pathophysiology:

Vascular Endothelial Function and Blood Pressure Homeostasis in Mice Overexpressing IGF Binding Protein-1: Stephen B. Wheatcroft, Mark T. Kearney, Ajay M. Shah, David J. Grieve, Ian L. Williams, John P. Miell, and Paul A. Crossey
Diabetes 2003 52: 2075 -2082. [Abstract] [Full Text] [PDF]

Cortisol Elevations Comparable to Those That Occur During Hypoglycemia Do Not Cause Hypoglycemia-Associated Autonomic Failure: Bharathi Raju, Veronica P. McGregor, and Philip E. Cryer
Diabetes 2003 52: 2083 -2089. [Abstract] [Full Text] [PDF]

Higher Offspring Birth Weight Predicts the Metabolic Syndrome in Mothers but Not Fathers 8 Years After Delivery: The Pune Children’s Study: Chittaranjan S. Yajnik, Charu V. Joglekar, Anand N. Pandit, Ashish R. Bavdekar, Swati A. Bapat, Sheila A. Bhave, Samantha D. Leary, and Caroline H.D. Fall
Diabetes 2003 52: 2090 -2096. [Abstract] [Full Text] [PDF]

Inflammation-Sensitive Plasma Proteins Are Associated With Future Weight Gain: Gunnar Engström, Bo Hedblad, Lars Stavenow, Peter Lind, Lars Janzon, and Folke Lindgärde
Diabetes 2003 52: 2097 -2101. [Abstract] [Full Text] [PDF]

Complications:

Protein Kinase Cß Selective Inhibitor LY333531 Attenuates Diabetic Hyperalgesia Through Ameliorating cGMP Level of Dorsal Root Ganglion Neurons: Hyoh Kim, Teiji Sasaki, Kengo Maeda, Daisuke Koya, Atsunori Kashiwagi, and Hitoshi Yasuda
Diabetes 2003 52: 2102 -2109. [Abstract] [Full Text] [PDF]

Prevention of Incipient Diabetic Nephropathy by High-Dose Thiamine and Benfotiamine: Roya Babaei-Jadidi, Nikolaos Karachalias, Naila Ahmed, Sinan Battah, and Paul J. Thornalley
Diabetes 2003 52: 2110 -2120. [Abstract] [Full Text] [PDF]

Leptin Increases Lipoprotein Lipase Secretion by Macrophages: Involvement of Oxidative Stress and Protein Kinase C: Fritz Maingrette and Geneviève Renier
Diabetes 2003 52: 2121 -2128. [Abstract] [Full Text] [PDF]

Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia: Tze-Jen Huang, Sally A. Price, Lucy Chilton, Nigel A. Calcutt, David R. Tomlinson, Alex Verkhratsky, and Paul Fernyhough
Diabetes 2003 52: 2129 -2136. [Abstract] [Full Text] [PDF]

Production of N-(Carboxymethyl)Lysine Is Impaired in Mice Deficient in NADPH Oxidase: A Role for Phagocyte-Derived Oxidants in the Formation of Advanced Glycation End Products During Inflammation: Melissa M. Anderson and Jay W. Heinecke
Diabetes 2003 52: 2137 -2143. [Abstract] [Full Text] [PDF]

Expression of Constitutively Active cGMP-Dependent Protein Kinase Prevents Glucose Stimulation of Thrombospondin 1 Expression and TGF-ß Activity: Shuxia Wang, Xing Wu, Thomas M. Lincoln, and Joanne E. Murphy-Ullrich
Diabetes 2003 52: 2144 -2150. [Abstract] [Full Text] [PDF]

Genetics:

Microarray Analysis of Gene Expression in the Kidneys of New- and Post-Onset Diabetic NOD Mice: Karen H.S. Wilson, Sarah E. Eckenrode, Quan-Zhen Li, Qing-Guo Ruan, Ping Yang, Jing-Da Shi, Abdoreza Davoodi-Semiromi, Richard A. McIndoe, Byron P. Croker, and Jin-Xiong She
Diabetes 2003 52: 2151 -2159. [Abstract] [Full Text] [PDF]

Prevalence and Characteristics of the Metabolic Syndrome in the San Antonio Heart and Framingham Offspring Studies: James B. Meigs, Peter W.F. Wilson, David M. Nathan, Ralph B. D’Agostino, Sr., Ken Williams, and Steven M. Haffner
Diabetes 2003 52: 2160 -2167. [Abstract] [Full Text] [PDF]

Minimal Model-Based Insulin Sensitivity Has Greater Heritability and a Different Genetic Basis Than Homeostasis Model Assessment or Fasting Insulin: Richard N. Bergman, Daniel J. Zaccaro, Richard M. Watanabe, Steven M. Haffner, Mohammed F. Saad, Jill M. Norris, Lynne E. Wagenknecht, James E. Hokanson, Jerome I. Rotter, and Steven S. Rich
Diabetes 2003 52: 2168 -2174. [Abstract] [Full Text] [PDF]

Identification of Epistatic Interaction Involved in Obesity Using the KK/Ta Mouse as a Type 2 Diabetes Model: Is Zn- ${alpha}$ ₂ Glycoprotein-1 a Candidate Gene for Obesity?: Tomohito Gohda, Yuichiro Makita, Toshihide Shike, Mitsuo Tanimoto, Kazuhiko Funabiki, Satoshi Horikoshi, and Yasuhiko Tomino
Diabetes 2003 52: 2175 -2181. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

Genetic Modifiers of the Age at Diagnosis of Diabetes (MODY3) in Carriers of Hepatocyte Nuclear Factor-1 ${alpha}$ Mutations Map to Chromosomes 5p15, 9q22, and 14q24: Sung-Hoon Kim, Xiaowei Ma, Tomasz Klupa, Christine Powers, Marcus Pezzolesi, James H. Warram, Stephen S. Rich, Andrzej S. Krolewski, and Alessandro Doria
Diabetes 2003 52: 2182 -2186. [Abstract] [Full Text] [PDF]