Banting Lecture 2003:

Autoimmune Diabetes and the Circle of Tolerance

Aldo A. Rossini
Diabetes 2004 53: 267 -275. [Abstract] [Full Text] [PDF]  

Perspectives in Diabetes:

Chronic Sympathetic Activation: Consequence and Cause of Age-Associated Obesity?

Douglas R. Seals and Christopher Bell
Diabetes 2004 53: 276 -284. [Abstract] [Full Text] [PDF]  

Metabolism:

Suppression of Endogenous Glucose Production by Mild Hyperinsulinemia During Exercise Is Determined Predominantly by Portal Venous Insulin

Raul C. Camacho, R. Richard Pencek, D. Brooks Lacy, Freyja D. James, and David H. Wasserman
Diabetes 2004 53: 285 -293. [Abstract] [Full Text] [PDF]  

Strength Training Increases Insulin-Mediated Glucose Uptake, GLUT4 Content, and Insulin Signaling in Skeletal Muscle in Patients With Type 2 Diabetes

Mads K. Holten, Morten Zacho, Michael Gaster, Carsten Juel, Jørgen F.P. Wojtaszewski, and Flemming Dela
Diabetes 2004 53: 294 -305. [Abstract] [Full Text] [PDF]  

Hexokinase II Overexpression Improves Exercise-Stimulated But Not Insulin-Stimulated Muscle Glucose Uptake in High-Fat-Fed C57BL/6J Mice

Patrick T. Fueger, Deanna P. Bracy, Carlo M. Malabanan, R. Richard Pencek, Daryl K. Granner, and David H. Wasserman
Diabetes 2004 53: 306 -314. [Abstract] [Full Text] [PDF]  

Effect of Moderate Exercise Training on Peripheral Glucose Effectiveness, Insulin Sensitivity, and Endogenous Glucose Production in Healthy Humans Estimated by a Two-Compartment-Labeled Minimal Model

Yuichiro Nishida, Kumpei Tokuyama, Shoichiro Nagasaka, Yasuki Higaki, Yoko Shirai, Akira Kiyonaga, Munehiro Shindo, Ikuyo Kusaka, Tomoatsu Nakamura, Shun Ishibashi, and Hiroaki Tanaka
Diabetes 2004 53: 315 -320. [Abstract] [Full Text] [PDF]  

Signal Transduction:

Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells

Yvan Gosmain, Etienne Lefai, Stephan Ryser, Marina Roques, and Hubert Vidal
Diabetes 2004 53: 321 -329. [Abstract] [Full Text] [PDF]  

Ca²⁺ and AMPK Both Mediate Stimulation of Glucose Transport by Muscle Contractions

David C. Wright, Kathleen A. Hucker, John O. Holloszy, and Dong Ho Han
Diabetes 2004 53: 330 -335. [Abstract] [Full Text] [PDF]  

Obesity Study:

Prevention of Obesity and Insulin Resistance in Mice Lacking Plasminogen Activator Inhibitor 1

Li-Jun Ma, Su-Li Mao, Kevin L. Taylor, Talerngsak Kanjanabuch, YouFei Guan, YaHua Zhang, Nancy J. Brown, Larry L. Swift, Owen P. McGuinness, David H. Wasserman, Douglas E. Vaughan, and Agnes B. Fogo
Diabetes 2004 53: 336 -346. [Abstract] [Full Text] [PDF]  

Leptin Impairs Insulin Signaling in Rat Adipocytes

Coralia Pérez, Carmen Fernández-Galaz, Teresa Fernández-Agulló, Carmen Arribas, Antonio Andrés, Manuel Ros, and José M. Carrascosa
Diabetes 2004 53: 347 -353. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Proinsulin Expression by Hassall’s Corpuscles in the Mouse Thymus

Aziz Alami Chentoufi, Michael Palumbo, and Constantin Polychronakos
Diabetes 2004 53: 354 -359. [Abstract] [Full Text] [PDF]  

Exercise Induces Hypoglycemia in Rats With Islet Transplantation

Abdulkadir Omer, Valérie F. Duvivier-Kali, William Aschenbach, Vaja Tchipashvili, Laurie J. Goodyear, and Gordon C. Weir
Diabetes 2004 53: 360 -365. [Abstract] [Full Text] [PDF]  

Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice

Sarah E. Eckenrode, Qingguo Ruan, Ping Yang, Weipeng Zheng, Richard A. McIndoe, and Jin-Xiong She
Diabetes 2004 53: 366 -375. [Abstract] [Full Text] [PDF]  

Mixed Hematopoietic Chimerism Allows Cure of Autoimmune Diabetes Through Allogeneic Tolerance and Reversal of Autoimmunity

Boris Nikolic, Yasuo Takeuchi, Igor Leykin, Yasuhiro Fudaba, R. Neal Smith, and Megan Sykes
Diabetes 2004 53: 376 -383. [Abstract] [Full Text] [PDF]  

Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics

Peter Achenbach, Katharina Warncke, Jürgen Reiter, Heike E. Naserke, Alistair J.K. Williams, Polly J. Bingley, Ezio Bonifacio, and Anette-G. Ziegler
Diabetes 2004 53: 384 -392. [Abstract] [Full Text] [PDF]  

Islet Studies:

Role for Plasma Membrane-Related Ca²⁺-ATPase-1 (ATP2C1) in Pancreatic ß-Cell Ca²⁺ Homeostasis Revealed by RNA Silencing

Kathryn J. Mitchell, Takashi Tsuboi, and Guy A. Rutter
Diabetes 2004 53: 393 -400. [Abstract] [Full Text] [PDF] Appendix  

Regulation of ATP/ADP in Pancreatic Islets

Ian R. Sweet, Daniel L. Cook, Eric DeJulio, Angela R. Wallen, Gamal Khalil, James Callis, and JoAnna Reems
Diabetes 2004 53: 401 -409. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in db/db Mice

Yin Liang, Melville C. Osborne, Brett P. Monia, Sanjay Bhanot, William A. Gaarde, Chantal Reed, Pengxiang She, Thomas L. Jetton, and Keith T. Demarest
Diabetes 2004 53: 410 -417. [Abstract] [Full Text] [PDF]  

Effect of Recurrent Hypoglycemia on Spatial Cognition and Cognitive Metabolism in Normal and Diabetic Rats

Ewan C. McNay and Robert S. Sherwin
Diabetes 2004 53: 418 -425. [Abstract] [Full Text] [PDF]  

Insulin Secretion in Type 1 Diabetes

Chynna Steele, William A. Hagopian, Stephen Gitelman, Umesh Masharani, Melissa Cavaghan, Kristina I. Rother, David Donaldson, David M. Harlan, Jeffrey Bluestone, and Kevan C. Herold
Diabetes 2004 53: 426 -433. [Abstract] [Full Text] [PDF]  

Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes: The Strong Heart Study

Peter M. Okin, Richard B. Devereux, Elisa T. Lee, James M. Galloway, and Barbara V. Howard
Diabetes 2004 53: 434 -440. [Abstract] [Full Text] [PDF]  

Decrease in Glucose-Stimulated Insulin Secretion With Aging Is Independent of Insulin Action

Radhika Muzumdar, Xiaohui Ma, Gil Atzmon, Patricia Vuguin, Xiaoman Yang, and Nir Barzilai
Diabetes 2004 53: 441 -446. [Abstract] [Full Text] [PDF]  

Insulin Sensitivity of Muscle Capillary Recruitment In Vivo

Lei Zhang, Michelle A. Vincent, Stephen M. Richards, Lucy H. Clerk, Stephen Rattigan, Michael G. Clark, and Eugene J. Barrett
Diabetes 2004 53: 447 -453. [Abstract] [Full Text] [PDF]  

Complication:

Absence of Inducible Nitric Oxide Synthase Reduces Myocardial Damage During Ischemia Reperfusion in Streptozotocin-Induced Hyperglycemic Mice

Raffaele Marfella, Clara Di Filippo, Katherine Esposito, Francesco Nappo, Elena Piegari, Salvatore Cuzzocrea, Liberato Berrino, Francesco Rossi, Dario Giugliano, and Michele D’Amico
Diabetes 2004 53: 454 -462. [Abstract] [Full Text] [PDF]  

Diabetes Increases Formation of Advanced Glycation End Products on Sarco(endo)plasmic Reticulum Ca²⁺-ATPase

Keshore R. Bidasee, Yinong Zhang, Chun Hong Shao, Mu Wang, Kaushik P. Patel, Ü. Deniz Dincer, and Henry R. Besch
Diabetes 2004 53: 463 -473. [Abstract] [Full Text] [PDF]  

Genetics:

Increased Risk of Type 2 Diabetes in Alzheimer Disease

Juliette Janson, Thomas Laedtke, Joseph E. Parisi, Peter O’Brien, Ronald C. Petersen, and Peter C. Butler
Diabetes 2004 53: 474 -481. [Abstract] [Full Text] [PDF]  

Uncoupling Protein 2 Promoter Polymorphism -866G/A Affects Its Expression in ß-Cells and Modulates Clinical Profiles of Japanese Type 2 Diabetic Patients

Miyoshi Sasahara, Masahiro Nishi, Hiromichi Kawashima, Kazuya Ueda, Setsuya Sakagashira, Hiroto Furuta, Eisaku Matsumoto, Tadashi Hanabusa, Hideyuki Sasaki, and Kishio Nanjo
Diabetes 2004 53: 482 -485. [Abstract] [Full Text] [PDF]  

Examination of Candidate Chromosomal Regions for Type 2 Diabetes Reveals a Susceptibility Locus on Human Chromosome 8p23.1

Marcus G. Pezzolesi, Moonsuk Nam, Terumasa Nagase, Tomasz Klupa, Jonathon S. Dunn, Wojciech M. Mlynarski, Stephen S. Rich, James H. Warram, and Andrzej S. Krolewski
Diabetes 2004 53: 486 -491. [Abstract] [Full Text] [PDF] Appendix  

Linkage and Association Mapping of a Chromosome 1q21-q24 Type 2 Diabetes Susceptibility Locus in Northern European Caucasians

Swapan Kumar Das, Sandra J. Hasstedt, Zhengxian Zhang, and Steven C. Elbein
Diabetes 2004 53: 492 -499. [Abstract] [Full Text] [PDF] Appendix  

Brief Genetics Reports:

Messenger RNA Transcripts of the Hepatocyte Nuclear Factor-1 Gene Containing Premature Termination Codons Are Subject to Nonsense-Mediated Decay

Lorna W. Harries, Andrew T. Hattersley, and Sian Ellard
Diabetes 2004 53: 500 -504. [Abstract] [Full Text] [PDF]  

Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb

Felicity Payne, Deborah J. Smyth, Rebecca Pask, Bryan J. Barratt, Jason D. Cooper, Rebecca C.J. Twells, Neil M. Walker, Alex C. Lam, Luc J. Smink, Sarah Nutland, Helen E. Rance, and John A. Todd
Diabetes 2004 53: 505 -509. [Abstract] [Full Text] [PDF]  

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