Diabetes -- Table of Contents (April 2004, 53 [4])

Metabolism:

Inhalation of Insulin in Dogs: Assessment of Insulin Levels and Comparison to Subcutaneous Injection: Alan D. Cherrington, Doss W. Neal, Dale S. Edgerton, Dana Glass, Larry Bowen, Charles H. Hobbs, Chet Leach, Ralf Rosskamp, and Thomas R. Strack
Diabetes 2004 53: 877 -881. [Abstract] [Full Text] [PDF]

Signal Transduction:

Modulation of Resistin Expression by Retinoic Acid and Vitamin A Status: Francisco Felipe, M. Luisa Bonet, Joan Ribot, and Andreu Palou
Diabetes 2004 53: 882 -889. [Abstract] [Full Text] [PDF]

Glucose Regulates the Expression of the Farnesoid X Receptor in Liver: Daniel Duran-Sandoval, Gisèle Mautino, Geneviève Martin, Fréderic Percevault, Olivier Barbier, Jean-Charles Fruchart, Folkert Kuipers, and Bart Staels
Diabetes 2004 53: 890 -898. [Abstract] [Full Text] [PDF]

Protein Kinase B- ${alpha}$ Inhibits Human Pyruvate Dehydrogenase Kinase-4 Gene Induction by Dexamethasone Through Inactivation of FOXO Transcription Factors: Hye-Sook Kwon, Boli Huang, Terry G. Unterman, and Robert A. Harris
Diabetes 2004 53: 899 -910. [Abstract] [Full Text] [PDF]

Ciliary Neurotrophic Factor and Leptin Induce Distinct Patterns of Immediate Early Gene Expression in the Brain: Joseph F. Kelly, Carol F. Elias, Charlotte E. Lee, Rexford S. Ahima, Randy J. Seeley, Christian Bjørbæk, Takakazu Oka, Clifford B. Saper, Jeffrey S. Flier, and Joel K. Elmquist
Diabetes 2004 53: 911 -920. [Abstract] [Full Text] [PDF]

Prolonged Incubation in PUGNAc Results in Increased Protein O-Linked Glycosylation and Insulin Resistance in Rat Skeletal Muscle: Edward B. Arias, Junghoon Kim, and Gregory D. Cartee
Diabetes 2004 53: 921 -930. [Abstract] [Full Text] [PDF]

Obesity Study:

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11ß-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice: Nicholas M. Morton, Janice M. Paterson, Hiroaki Masuzaki, Megan C. Holmes, Bart Staels, Catherine Fievet, Brian R. Walker, Jeffrey S. Flier, John J. Mullins, and Jonathan R. Seckl
Diabetes 2004 53: 931 -938. [Abstract] [Full Text] [PDF]

Restoration of Adiponectin Pulsatility in Severely Obese Subjects After Weight Loss: Menotti Calvani, Antonio Scarfone, Luigi Granato, Elena Valera Mora, Giuseppe Nanni, Marco Castagneto, Aldo V. Greco, Melania Manco, and Geltrude Mingrone
Diabetes 2004 53: 939 -947. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Evidence of Functional Impairment of Syngeneically Transplanted Mouse Pancreatic Islets Retrieved from the Liver: Göran Mattsson, Leif Jansson, Astrid Nordin, Arne Andersson, and Per-Ola Carlsson
Diabetes 2004 53: 948 -954. [Abstract] [Full Text] [PDF]

Assessment of the Severity of Hypoglycemia and Glycemic Lability in Type 1 Diabetic Subjects Undergoing Islet Transplantation: Edmond A. Ryan, Tami Shandro, Kristy Green, Breay W. Paty, Peter A. Senior, David Bigam, A.M. James Shapiro, and Marie-Christine Vantyghem
Diabetes 2004 53: 955 -962. [Abstract] [Full Text] [PDF] Online appendix

Elevated Vascular Endothelial Growth Factor Production in Islets Improves Islet Graft Vascularization: Nan Zhang, Anja Richter, Jenny Suriawinata, Sonal Harbaran, Jennifer Altomonte, Lin Cong, Haojiang Zhang, Keying Song, Marcia Meseck, Jonathan Bromberg, and Hengjiang Dong
Diabetes 2004 53: 963 -970. [Abstract] [Full Text] [PDF]

Differential Recognition and Activation Thresholds in Human Autoreactive GAD-Specific T-Cells: Roberto Mallone, Sharon A. Kochik, Elsa M. Laughlin, Vivian H. Gersuk, Helena Reijonen, William W. Kwok, and Gerald T. Nepom
Diabetes 2004 53: 971 -977. [Abstract] [Full Text] [PDF]

T-Cell Receptor Transgenic Response to an Endogenous Polymorphic Autoantigen Determines Susceptibility to Diabetes: Mary E. Pauza, Cathleen M. Dobbs, Jing He, Tricia Patterson, Steven Wagner, Brian S. Anobile, Brenda J. Bradley, David Lo, and Kathryn Haskins
Diabetes 2004 53: 978 -988. [Abstract] [Full Text] [PDF]

Islet Study:

Improved Islet Morphology after Blockade of the Renin- Angiotensin System in the ZDF Rat: Christos Tikellis, Peter J. Wookey, Riccardo Candido, Sof Andrikopoulos, Merlin C. Thomas, and Mark E. Cooper
Diabetes 2004 53: 989 -997. [Abstract] [Full Text] [PDF]

Metabotropic Glutamate Receptor Type 4 Is Involved in Autoinhibitory Cascade for Glucagon Secretion by ${alpha}$ -Cells of Islet of Langerhans: Shunsuke Uehara, Akiko Muroyama, Noriko Echigo, Riyo Morimoto, Masato Otsuka, Shouki Yatsushiro, and Yoshinori Moriyama
Diabetes 2004 53: 998 -1006. [Abstract] [Full Text] [PDF]

A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli: Raphaël Roduit, Christopher Nolan, Cristina Alarcon, Patrick Moore, Annie Barbeau, Viviane Delghingaro-Augusto, Ewa Przybykowski, Johane Morin, Frédéric Massé, Bernard Massie, Neil Ruderman, Christopher Rhodes, Vincent Poitout, and Marc Prentki
Diabetes 2004 53: 1007 -1019. [Abstract] [Full Text] [PDF]

Interaction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFK-2/FBPase-2) With Glucokinase Activates Glucose Phosphorylation and Glucose Metabolism in Insulin-Producing Cells: Laura Massa, Simone Baltrusch, David A. Okar, Alex J. Lange, Sigurd Lenzen, and Markus Tiedge
Diabetes 2004 53: 1020 -1029. [Abstract] [Full Text] [PDF]

Regulated Expression of pdx-1 Promotes In Vitro Differentiation of Insulin-Producing Cells From Embryonic Stem Cells: Satsuki Miyazaki, Eiji Yamato, and Jun-ichi Miyazaki
Diabetes 2004 53: 1030 -1037. [Abstract] [Full Text] [PDF]

Glucose Inhibition of Glucagon Secretion From Rat ${alpha}$ -Cells Is Mediated by GABA Released From Neighboring ß-Cells: Anna Wendt, Bryndis Birnir, Karsten Buschard, Jesper Gromada, Albert Salehi, Sabine Sewing, Patrik Rorsman, and Matthias Braun
Diabetes 2004 53: 1038 -1045. [Abstract] [Full Text] [PDF]

Pathophysiology:

Diabetic Patients Without Vascular Complications Display Enhanced Basal Platelet Activation and Decreased Antioxidant Status: Evelyne Véricel, Caroline Januel, Martine Carreras, Philippe Moulin, and Michel Lagarde
Diabetes 2004 53: 1046 -1051. [Abstract] [Full Text] [PDF]

Thiazolidinediones, Like Metformin, Inhibit Respiratory Complex I: A Common Mechanism Contributing to Their Antidiabetic Actions?: Barbara Brunmair, Katrin Staniek, Florian Gras, Nicole Scharf, Aleksandra Althaym, Renate Clara, Michael Roden, Erich Gnaiger, Hans Nohl, Werner Waldhäusl, and Clemens Fürnsinn
Diabetes 2004 53: 1052 -1059. [Abstract] [Full Text] [PDF]

Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo: Hyo-Jeong Kim, Takamasa Higashimori, So-Young Park, Hyejeong Choi, Jianying Dong, Yoon-Jung Kim, Hye-Lim Noh, You-Ree Cho, Gary Cline, Young-Bum Kim, and Jason K. Kim
Diabetes 2004 53: 1060 -1067. [Abstract] [Full Text] [PDF]

The Metabolic Syndrome, Circulating Oxidized LDL, and Risk of Myocardial Infarction in Well-Functioning Elderly People in the Health, Aging, and Body Composition Cohort: Paul Holvoet, Stephen B. Kritchevsky, Russell P. Tracy, Ann Mertens, Susan M. Rubin, Javed Butler, Bret Goodpaster, and Tamara B. Harris
Diabetes 2004 53: 1068 -1073. [Abstract] [Full Text] [PDF]

Hexosamine Pathway Is Responsible for Inhibition by Diabetes of Phenylephrine-Induced Inotropy: Yi Pang, Pam Bounelis, John C. Chatham, and Richard B. Marchase
Diabetes 2004 53: 1074 -1081. [Abstract] [Full Text] [PDF]

Oxidative Stress Impairs Skeletal Muscle Repair in Diabetic Rats: Manuela Aragno, Raffaella Mastrocola, Maria Graziella Catalano, Enrico Brignardello, Oliviero Danni, and Giuseppe Boccuzzi
Diabetes 2004 53: 1082 -1088. [Abstract] [Full Text] [PDF]

Improved ß-Cell Survival and Reduced Insulitis in a Type 1 Diabetic Rat Model After Treatment With a ß-Cell–Selective K_ATP Channel Opener: Kresten Skak, Carsten F. Gotfredsen, Dorthe Lundsgaard, John Bondo Hansen, Jeppe Sturis, and Helle Markholst
Diabetes 2004 53: 1089 -1095. [Abstract] [Full Text] [PDF]

Complication:

Prophylactic Gene Therapy With Human Tissue Kallikrein Ameliorates Limb Ischemia Recovery in Type 1 Diabetic Mice: Costanza Emanueli, Galliam Graiani, Maria B. Salis, Sergio Gadau, Elisa Desortes, and Paolo Madeddu
Diabetes 2004 53: 1096 -1103. [Abstract] [Full Text] [PDF]

Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina: Evidence for Involvement in Diabetic Retinopathy: Hans-Peter Hammes, Jihong Lin, Patrick Wagner, Yuxi Feng, Franziska vom Hagen, Thomas Krzizok, Oliver Renner, Georg Breier, Michael Brownlee, and Urban Deutsch
Diabetes 2004 53: 1104 -1110. [Abstract] [Full Text] [PDF]

Transforming Growth Factor-ß1 Production Is Correlated With Genetically Determined ACE Expression in Congenic Rats: A Possible Link Between ACE Genotype and Diabetic Nephropathy: Maria E. Pueyo, Mireille Challah, Dominique Gauguier, Liliane Louedec, Monique Philippe, Roger Gaertner, Michel Marre, Jean-Baptiste Michel, and Marie-Paule Jacob
Diabetes 2004 53: 1111 -1118. [Abstract] [Full Text] [PDF]

Regression of Advanced Diabetic Nephropathy by Hepatocyte Growth Factor Gene Therapy in Rats: Josep M. Cruzado, Núria Lloberas, Joan Torras, Marta Riera, Cristina Fillat, Immaculada Herrero-Fresneda, Josep M. Aran, Gabriela Alperovich, August Vidal, and Josep M. Grinyó
Diabetes 2004 53: 1119 -1127. [Abstract] [Full Text] [PDF]

Genetics:

Maternal-Fetal Interactions and Birth Order Influence Insulin Variable Number of Tandem Repeats Allele Class Associations with Head Size at Birth and Childhood Weight Gain: Ken K. Ong, Clive J. Petry, Bryan J. Barratt, Susan Ring, Heather J. Cordell, Diane L. Wingate, Marcus E. Pembrey, John A. Todd, and David B. Dunger
Diabetes 2004 53: 1128 -1133. [Abstract] [Full Text] [PDF]

A Common Polymorphism in the Upstream Promoter Region of the Hepatocyte Nuclear Factor-4 ${alpha}$ Gene on Chromosome 20q Is Associated With Type 2 Diabetes and Appears to Contribute to the Evidence for Linkage in an Ashkenazi Jewish Population: Latisha D. Love-Gregory, Jonathon Wasson, Jiyan Ma, Carol H. Jin, Benjamin Glaser, Brian K. Suarez, and M. Alan Permutt
Diabetes 2004 53: 1134 -1140. First published on April 12, 2004 as 10.2337/diabetes.53.4.1134 [Abstract] [Full Text] [PDF] Data Supplement

Genetic Variation Near the Hepatocyte Nuclear Factor-4 ${alpha}$ Gene Predicts Susceptibility to Type 2 Diabetes: Kaisa Silander, Karen L. Mohlke, Laura J. Scott, Erin C. Peck, Pablo Hollstein, Andrew D. Skol, Anne U. Jackson, Panagiotis Deloukas, Sarah Hunt, George Stavrides, Peter S. Chines, Michael R. Erdos, Narisu Narisu, Karen N. Conneely, Chun Li, Tasha E. Fingerlin, Sharanjeet K. Dhanjal, Timo T. Valle, Richard N. Bergman, Jaakko Tuomilehto, Richard M. Watanabe, Michael Boehnke, and Francis S. Collins
Diabetes 2004 53: 1141 -1149. First published on March 9, 2004 as 10.2337/diabetes.53.4.1141 [Abstract] [Full Text] [PDF] Supplemental Data

Brief Genetics Reports:

Adiponectin Gene Polymorphisms and Adiponectin Levels Are Independently Associated With the Development of Hyperglycemia During a 3-Year Period: The Epidemiologic Data on the Insulin Resistance Syndrome Prospective Study: Frédéric Fumeron, Roberte Aubert, Afshan Siddiq, Dina Betoulle, Frank Péan, Samy Hadjadj, Jean Tichet, Elsie Wilpart, Marie-Claude Chesnier, Beverley Balkau, Philippe Froguel, and Michel Marre
Diabetes 2004 53: 1150 -1157. [Abstract] [Full Text] [PDF] Online appendixes

Lack of Association of the Ala⁴⁵Thr Polymorphism and Other Common Variants of the NeuroD Gene With Type 1 Diabetes: Adrian Vella, Joanna M.M. Howson, Bryan J. Barratt, Rebecca C.J. Twells, Helen E. Rance, Sarah Nutland, Eva Tuomilehto-Wolf, Jaakko Tuomilehto, Dag E. Undlien, Kjersti S. Rønningen, Cristian Guja, Constantin Ionescu-Tîrgoviste, David A. Savage, and John A. Todd
Diabetes 2004 53: 1158 -1161. [Abstract] [Full Text] [PDF] Online appendix

Association Between Variation in the Actin-Binding Gene Caldesmon and Diabetic Nephropathy in Type 1 Diabetes: Bryan R. Conway, A. Peter Maxwell, David A. Savage, Chris C. Patterson, Peter P. Doran, Madeline Murphy, Hugh R. Brady, and Damian G. Fogarty
Diabetes 2004 53: 1162 -1165. [Abstract] [Full Text] [PDF]

Heritability of Multivariate Factors of the Metabolic Syndrome in Nondiabetic Japanese Americans: Melissa A. Austin, Karen L. Edwards, Marguerite J. McNeely, Wayne L. Chandler, Donna L. Leonetti, Philippa J. Talmud, Steve E. Humphries, and Wilfred Y. Fujimoto
Diabetes 2004 53: 1166 -1169. [Abstract] [Full Text] [PDF]

Linkage of the Metabolic Syndrome to 1q23-q31 in Hispanic Families: The Insulin Resistance Atherosclerosis Study Family Study: Carl D. Langefeld, Lynne E. Wagenknecht, Jerome I. Rotter, Adrienne H. Williams, John E. Hokanson, Mohammad F. Saad, Donald W. Bowden, Stephen Haffner, Jill M. Norris, Stephen S. Rich, and Braxton D. Mitchell
Diabetes 2004 53: 1170 -1174. [Abstract] [Full Text] [PDF]

Errata:

Erratum: Diabetes 2004 53: 1175 -1176. [Extract] [Full Text] [PDF]

Erratum: Diabetes 2004 53: 1177 -1178. [Extract] [Full Text] [PDF]