Perspectives in Diabetes:

Genetic Studies of the Etiology of Type 2 Diabetes in Pima Indians: Hunting for Pieces to a Complicated Puzzle

Leslie J. Baier and Robert L. Hanson
Diabetes 2004 53: 1181 -1186. [Extract] [Full Text] [PDF] Appendix  

Metabolism:

One Week’s Treatment With the Long-Acting Glucagon-Like Peptide 1 Derivative Liraglutide (NN2211) Markedly Improves 24-h Glycemia and - and ß-Cell Function and Reduces Endogenous Glucose Release in Patients with Type 2 Diabetes

Kristine B. Degn, Claus B. Juhl, Jeppe Sturis, Grethe Jakobsen, Birgitte Brock, Visvanathan Chandramouli, Joergen Rungby, Bernard R. Landau, and Ole Schmitz
Diabetes 2004 53: 1187 -1194. [Abstract] [Full Text] [PDF]  

Relationship to Insulin Resistance of the Adult Treatment Panel III Diagnostic Criteria for Identification of the Metabolic Syndrome

Karen L. Cheal, Fahim Abbasi, Cindy Lamendola, Tracey McLaughlin, Gerald M. Reaven, and Earl S. Ford
Diabetes 2004 53: 1195 -1200. [Abstract] [Full Text] [PDF]  

Evaluation of Insulin Sensitivity and ß-Cell Function Indexes Obtained From Minimal Model Analysis of a Meal Tolerance Test

Garry M. Steil, Chi-min Hwu, Robert Janowski, Farzam Hariri, Sujata Jinagouda, Christine Darwin, Sameh Tadros, Kerstin Rebrin, and Mohammed F. Saad
Diabetes 2004 53: 1201 -1207. [Abstract] [Full Text] [PDF]  

Signal Transduction:

Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle

Sean L. McGee and Mark Hargreaves
Diabetes 2004 53: 1208 -1214. [Abstract] [Full Text] [PDF]  

Relationship Between Insulin Sensitivity and Sphingomyelin Signaling Pathway in Human Skeletal Muscle

Marek Straczkowski, Irina Kowalska, Agnieszka Nikolajuk, Stella Dzienis-Straczkowska, Ida Kinalska, Marcin Baranowski, Malgorzata Zendzian-Piotrowska, Zofia Brzezinska, and Jan Gorski
Diabetes 2004 53: 1215 -1221. [Abstract] [Full Text] [PDF]  

Bifunctional Properties of Peroxisome Proliferator-Activated Receptor 1 in KDR Gene Regulation Mediated via Interaction With Both Sp1 and Sp3

Yukio Sassa, Yasuaki Hata, Lloyd Paul Aiello, Yukio Taniguchi, Kimitoshi Kohno, and Tatsuro Ishibashi
Diabetes 2004 53: 1222 -1229. [Abstract] [Full Text] [PDF] Data Supplement  

Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses

Nicole M. Sanders, Ambrose A. Dunn-Meynell, and Barry E. Levin
Diabetes 2004 53: 1230 -1236. [Abstract] [Full Text] [PDF]  

Obesity Study:

Effects of Diabetes and Insulin on the Expression of Galanin-Like Peptide in the Hypothalamus of the Rat

Gregory S. Fraley, Jarrad M. Scarlett, Issei Shimada, Dawit N. Teklemichael, Blake V. Acohido, Donald K. Clifton, and Robert A. Steiner
Diabetes 2004 53: 1237 -1242. [Abstract] [Full Text] [PDF]  

Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-

Knut Tomas Dalen, Kristina Schoonjans, Stine M. Ulven, Mina Susanne Weedon-Fekjaer, Trine Gjesti Bentzen, Hana Koutnikova, Johan Auwerx, and Hilde I. Nebb
Diabetes 2004 53: 1243 -1252. [Abstract] [Full Text] [PDF] Data Supplement  

Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier

William A. Banks, Alan B. Coon, Sandra M. Robinson, Asif Moinuddin, Jessica M. Shultz, Ryota Nakaoke, and John E. Morley
Diabetes 2004 53: 1253 -1260. [Abstract] [Full Text] [PDF]  

Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation

Alex W. Cohen, Babak Razani, William Schubert, Terence M. Williams, Xiao Bo Wang, Puneeth Iyengar, Dawn L. Brasaemle, Philipp E. Scherer, and Michael P. Lisanti
Diabetes 2004 53: 1261 -1270. [Abstract] [Full Text] [PDF]  

Effects of Dietary Monosaccharides on Sympathetic Nervous System Activity in Adipose Tissues of Male Rats

James B. Young, Jeffrey Weiss, and Nadine Boufath
Diabetes 2004 53: 1271 -1278. [Abstract] [Full Text] [PDF]  

High Serum Resistin Is Associated With an Increase in Adiposity But Not a Worsening of Insulin Resistance in Pima Indians

Barbora Vozarova de Courten, Mikako Degawa-Yamauchi, Robert V. Considine, and P. Antonio Tataranni
Diabetes 2004 53: 1279 -1284. [Abstract] [Full Text] [PDF]  

From Blood Monocytes to Adipose Tissue-Resident Macrophages: Induction of Diapedesis by Human Mature Adipocytes

Cyrile A. Curat, Alexandra Miranville, Coralie Sengenès, Michael Diehl, Carolin Tonus, Rudi Busse, and Anne Bouloumié
Diabetes 2004 53: 1285 -1292. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Islet Cell Autoimmunity in a Triethnic Adult Population of the Third National Health and Nutrition Examination Survey

Emma Barinas-Mitchell, Susan Pietropaolo, Ying-Jian Zhang, Tyona Henderson, Massimo Trucco, Lewis H. Kuller, and Massimo Pietropaolo
Diabetes 2004 53: 1293 -1302. [Abstract] [Full Text] [PDF]  

Interleukin-4 but not Interleukin-10 Protects Against Spontaneous and Recurrent Type 1 Diabetes by Activated CD1d-Restricted Invariant Natural Killer T-Cells

Qing-Sheng Mi, Dalam Ly, Peter Zucker, Megan McGarry, and Terry L. Delovitch
Diabetes 2004 53: 1303 -1310. [Abstract] [Full Text] [PDF]  

Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function

Ravi Bhargava, Peter A. Senior, Thomas E. Ackerman, Edmond A. Ryan, Breay W. Paty, Jonathan R.T. Lakey, and A.M. James Shapiro
Diabetes 2004 53: 1311 -1317. [Abstract] [Full Text] [PDF]  

Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets

Marcela Brissova, Michael Fowler, Peter Wiebe, Alena Shostak, Masakazu Shiota, Aramandla Radhika, P. Charles Lin, Maureen Gannon, and Alvin C. Powers
Diabetes 2004 53: 1318 -1325. [Abstract] [Full Text] [PDF] Data SupplementInstructions and legends for supplemental data.  

Islet Study:

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Tanya Hansotia, Laurie L. Baggio, Dominique Delmeire, Simon A. Hinke, Yuichiro Yamada, Katsushi Tsukiyama, Yutaka Seino, Jens J. Holst, Frans Schuit, and D.J. Drucker
Diabetes 2004 53: 1326 -1335. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Catalase Protects Cardiomyocyte Function in Models of Type 1 and Type 2 Diabetes

Gang Ye, Naira S. Metreveli, Rajakumar V. Donthi, Shen Xia, Ming Xu, Edward C. Carlson, and Paul N. Epstein
Diabetes 2004 53: 1336 -1343. [Abstract] [Full Text] [PDF]  

Complication:

Insulin Generates Free Radicals by an NAD(P)H, Phosphatidylinositol 3'-Kinase-Dependent Mechanism in Human Skin Fibroblasts Ex Vivo

Giulio Ceolotto, Michela Bevilacqua, Italia Papparella, Elisabetta Baritono, Lorenzo Franco, Carlo Corvaja, Martina Mazzoni, Andrea Semplicini, and Angelo Avogaro
Diabetes 2004 53: 1344 -1351. [Abstract] [Full Text] [PDF]  

Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C

Benedek Erdös, James A. Snipes, Allison W. Miller, and David W. Busija
Diabetes 2004 53: 1352 -1359. [Abstract] [Full Text] [PDF]  

Genetics:

Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region

Jose C. Florez, Noël Burtt, Paul I.W. de Bakker, Peter Almgren, Tiinamaija Tuomi, Johan Holmkvist, Daniel Gaudet, Thomas J. Hudson, Steve F. Schaffner, Mark J. Daly, Joel N. Hirschhorn, Leif Groop, and David Altshuler
Diabetes 2004 53: 1360 -1368. [Abstract] [Full Text] [PDF] Appendix  

Genome-Wide Scans Reveal Quantitative Trait Loci on 8p and 13q Related to Insulin Action and Glucose Metabolism: The San Antonio Family Heart Study

Guowen Cai, Shelley A. Cole, Jeanne H. Freeland-Graves, Jean W. MacCluer, John Blangero, and Anthony G. Comuzzie
Diabetes 2004 53: 1369 -1374. [Abstract] [Full Text] [PDF]  

Identification of a Locus for Maturity-Onset Diabetes of the Young on Chromosome 8p23

Sung-Hoon Kim, Xiaowei Ma, Stanislawa Weremowicz, Tonino Ercolino, Christine Powers, Wojciech Mlynarski, K. Aviva Bashan, James H. Warram, Josyf Mychaleckyj, Stephen S. Rich, Andrzej S. Krolewski, and Alessandro Doria
Diabetes 2004 53: 1375 -1384. [Abstract] [Full Text] [PDF]  

Complex Haplotypes of the PGC-1 Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes

Hannes Oberkofler, Veronika Linnemayr, Raimund Weitgasser, Kerstin Klein, Mingqiang Xie, Bernhard Iglseder, Franz Krempler, Bernhard Paulweber, and Wolfgang Patsch
Diabetes 2004 53: 1385 -1393. [Abstract] [Full Text] [PDF] Appendix  

Brief Genetics Reports:

Investigation of the Human ANP Gene in Type 1 Diabetic Nephropathy: Case-Control and Follow-up Studies

Ronan Roussel, David-Alexandre Trégouët, Samy Hadjadj, Xavier Jeunemaître, and Michel Marre
Diabetes 2004 53: 1394 -1398. [Abstract] [Full Text] [PDF] Data Supplement  

Genome-Wide Linkage to Chromosome 6 for Waist Circumference in the Framingham Heart Study

Caroline S. Fox, Nancy L. Heard-Costa, Peter W.F. Wilson, Daniel Levy, Ralph B. D’Agostino, Sr., and Larry D. Atwood
Diabetes 2004 53: 1399 -1402. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Status of Research Funding by the American Diabetes Association—5th and Final Year

Mayer B. Davidson
Diabetes 2004 53: 1403 . [Extract] [Full Text] [PDF]  

Errata:

Erratum

Diabetes 2004 53: 1404 . [Extract] [Full Text] [PDF]  

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