Rapid Publications:

Abnormal Glucose Homeostasis due to Chronic Hyperresistinemia

Shamina M. Rangwala, A. Sophie Rich, Ben Rhoades, Jennifer S. Shapiro, Silvana Obici, Luciano Rossetti, and Mitchell A. Lazar
Diabetes 2004 53: 1937 -1941. First published on June 9, 2004 as 10.2337/diabetes.53.8.1937 [Abstract] [Full Text] [PDF]  

Perspectives in Diabetes:

Does the Glucose-Dependent Insulin Secretion Mechanism Itself Cause Oxidative Stress in Pancreatic ß-Cells?

Leonid E. Fridlyand and Louis H. Philipson
Diabetes 2004 53: 1942 -1948. [Abstract] [Full Text] [PDF]  

Signal Transduction:

PYY_3–36 Reinforces Insulin Action on Glucose Disposal in Mice Fed a High-Fat Diet

Anita M. van den Hoek, Annemieke C. Heijboer, Eleonora P.M. Corssmit, Peter J. Voshol, Johannes A. Romijn, Louis M. Havekes, and Hanno Pijl
Diabetes 2004 53: 1949 -1952. [Abstract] [Full Text] [PDF]  

Potential Role for AMP-Activated Protein Kinase in Hypoglycemia Sensing in the Ventromedial Hypothalamus

Rory J. McCrimmon, Xiaoning Fan, Yuyan Ding, Wanling Zhu, Ralph J. Jacob, and Robert S. Sherwin
Diabetes 2004 53: 1953 -1958. [Abstract] [Full Text] [PDF]  

Obesity Studies:

The Regulation of Glucose-Excited Neurons in the Hypothalamic Arcuate Nucleus by Glucose and Feeding-Relevant Peptides

R. Wang, X. Liu, S.T. Hentges, A.A. Dunn-Meynell, B.E. Levin, W. Wang, and V.H. Routh
Diabetes 2004 53: 1959 -1965. [Abstract] [Full Text] [PDF]  

Effects of Different Hypocaloric Diets on Protein Secretion From Adipose Tissue of Obese Women

Elisabet Arvidsson, Nathalie Viguerie, Ingalena Andersson, Camilla Verdich, Dominique Langin, and Peter Arner
Diabetes 2004 53: 1966 -1971. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice Is Controlled by Allelic Variants of Idd3

Todd Pearson, Peter Weiser, Thomas G. Markees, David V. Serreze, Linda S. Wicker, Laurence B. Peterson, Anne-Marie Cumisky, Leonard D. Shultz, John P. Mordes, Aldo A. Rossini, and Dale L. Greiner
Diabetes 2004 53: 1972 -1978. [Abstract] [Full Text] [PDF]  

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Gerben Bouma, Wai Kwan Lam-Tse, Annet F. Wierenga-Wolf, Hemmo A. Drexhage, and Marjan A. Versnel
Diabetes 2004 53: 1979 -1986. [Abstract] [Full Text] [PDF]  

GAD65-Specific CD4⁺ T-Cells with High Antigen Avidity Are Prevalent in Peripheral Blood of Patients With Type 1 Diabetes

Helena Reijonen, Roberto Mallone, Anne-Kristin Heninger, Elsa M. Laughlin, Sharon A. Kochik, Ben Falk, William W. Kwok, Carla Greenbaum, and Gerald T. Nepom
Diabetes 2004 53: 1987 -1994. [Abstract] [Full Text] [PDF]  

Flt3-Ligand Treatment Prevents Diabetes in NOD Mice

Paula M. Chilton, Francine Rezzoug, Isabelle Fugier-Vivier, Leslie A. Weeter, Hong Xu, Yiming Huang, Mukunda B. Ray, and Suzanne T. Ildstad
Diabetes 2004 53: 1995 -2002. [Abstract] [Full Text] [PDF]  

Hyperresponsiveness, Resistance to B-Cell Receptor—Dependent Activation-Induced Cell Death, and Accumulation of Hyperactivated B-Cells in Islets Is Associated With the Onset of Insulitis but not Type 1 Diabetes

Shabbir Hussain, Konstantin V. Salojin, and Terry L. Delovitch
Diabetes 2004 53: 2003 -2011. [Abstract] [Full Text] [PDF]  

Major Histocompatibility Complex Class I Shedding and Programmed Cell Death Stimulated Through the Proinflammatory P2X₇ Receptor: A Candidate Susceptibility Gene for NOD Diabetes

James I. Elliott and Christopher F. Higgins
Diabetes 2004 53: 2012 -2017. [Abstract] [Full Text] [PDF]  

Islet Studies:

Autocrine Regulation of Single Pancreatic ß-Cell Survival

Víctor Navarro-Tableros, M. Carmen Sánchez-Soto, Santiago García, and Marcia Hiriart
Diabetes 2004 53: 2018 -2023. [Abstract] [Full Text] [PDF]  

Inhibition of Activin Signaling Induces Pancreatic Epithelial Cell Expansion and Diminishes Terminal Differentiation of Pancreatic ß-Cells

You-Qing Zhang, Mary Malo Cleary, Yingjie Si, Guoxun Liu, Yuzuru Eto, Marcie Kritzik, Sandrine Dabernat, Ayse G. Kayali, and Nora Sarvetnick
Diabetes 2004 53: 2024 -2033. [Abstract] [Full Text] [PDF]  

Extracellular Matrix Protects Pancreatic ß-Cells Against Apoptosis: Role of Short- and Long-Term Signaling Pathways

Eva Hammar, Géraldine Parnaud, Domenico Bosco, Nadja Perriraz, Kathrin Maedler, Marc Donath, Dominique G. Rouiller, and Philippe A. Halban
Diabetes 2004 53: 2034 -2041. [Abstract] [Full Text] [PDF]  

Prospective Isolation of Multipotent Pancreatic Progenitors Using Flow-Cytometric Cell Sorting

Atsushi Suzuki, Hiromitsu Nakauchi, and Hideki Taniguchi
Diabetes 2004 53: 2143 -2152. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Insulin Dose-Response Curves for Stimulation of Splanchnic Glucose Uptake and Suppression of Endogenous Glucose Production Differ in Nondiabetic Humans and Are Abnormal in People With Type 2 Diabetes

Rita Basu, Ananda Basu, C. Michael Johnson, W. Frederick Schwenk, and Robert A. Rizza
Diabetes 2004 53: 2042 -2050. [Abstract] [Full Text] [PDF]  

Splanchnic Cortisol Production Occurs in Humans: Evidence for Conversion of Cortisone to Cortisol Via the 11-ß Hydroxysteroid Dehydrogenase (11ß-HSD) Type 1 Pathway

Rita Basu, Ravinder J. Singh, Ananda Basu, Elizabeth G. Chittilapilly, C. Michael Johnson, Gianna Toffolo, Claudio Cobelli, and Robert A. Rizza
Diabetes 2004 53: 2051 -2059. [Abstract] [Full Text] [PDF]  

Interactions Between Endothelin and Nitric Oxide in the Regulation of Vascular Tone in Obesity and Diabetes

Kieren J. Mather, Amale Lteif, Helmut O. Steinberg, and Alain D. Baron
Diabetes 2004 53: 2060 -2066. [Abstract] [Full Text] [PDF]  

Partial Gene Deletion of Endothelial Nitric Oxide Synthase Predisposes to Exaggerated High-Fat Diet—Induced Insulin Resistance and Arterial Hypertension

Stéphane Cook, Olivier Hugli, Marc Egli, Barbara Ménard, Sébastien Thalmann, Claudio Sartori, Christophe Perrin, Pascal Nicod, Bernard Thorens, Peter Vollenweider, Urs Scherrer, and Rémy Burcelin
Diabetes 2004 53: 2067 -2072. [Abstract] [Full Text] [PDF]  

Vasomotor Responses to Hypoxia in Type 2 Diabetes

Cara J. Weisbrod, Peter R. Eastwood, Gerard O’Driscoll, Jennifer H. Walsh, Matthew Best, John R. Halliwill, and Daniel J. Green
Diabetes 2004 53: 2073 -2078. [Abstract] [Full Text] [PDF]  

Proinflammatory Cytokines, Markers of Cardiovascular Risks, Oxidative Stress, and Lipid Peroxidation in Patients With Hyperglycemic Crises

Frankie B. Stentz, Guillermo E. Umpierrez, Ruben Cuervo, and Abbas E. Kitabchi
Diabetes 2004 53: 2079 -2086. [Abstract] [Full Text] [PDF]  

Intra-Abdominal Fat Is a Major Determinant of the National Cholesterol Education Program Adult Treatment Panel III Criteria for the Metabolic Syndrome

Darcy B. Carr, Kristina M. Utzschneider, Rebecca L. Hull, Keiichi Kodama, Barbara M. Retzlaff, John D. Brunzell, Jane B. Shofer, Brian E. Fish, Robert H. Knopp, and Steven E. Kahn
Diabetes 2004 53: 2087 -2094. [Abstract] [Full Text] [PDF]  

Impaired Glucose Tolerance, but not Impaired Fasting Glucose, Is Associated With Increased Levels of Coronary Heart Disease Risk Factors: Results From the Baltimore Longitudinal Study on Aging

Deirdre R. Blake, James B. Meigs, Denis C. Muller, Samer S. Najjar, Reubin Andres, and David M. Nathan
Diabetes 2004 53: 2095 -2100. [Abstract] [Full Text] [PDF]  

Complication:

Diminished Loss of Proteoglycans and Lack of Albuminuria in Protein Kinase C-—Deficient Diabetic Mice

Jan Menne, Joon-Keun Park, Martin Boehne, Marlies Elger, Carsten Lindschau, Torsten Kirsch, Matthias Meier, Faikah Gueler, Annette Fiebeler, Ferdinand H. Bahlmann, Michael Leitges, and Hermann Haller
Diabetes 2004 53: 2101 -2109. [Abstract] [Full Text] [PDF]  

Oxidative Stress Affects Synaptosomal -Aminobutyric Acid and Glutamate Transport in Diabetic Rats: The Role of Insulin

Ana I. Duarte, Maria S. Santos, Raquel Seiça, and Catarina R. Oliveira
Diabetes 2004 53: 2110 -2116. [Abstract] [Full Text] [PDF]  

Surface Expression of Collagen Receptor Fc Receptor-/Glycoprotein VI Is Enhanced on Platelets in Type 2 Diabetes and Mediates Release of CD40 Ligand and Activation of Endothelial Cells

Natalia Cabeza, Zhongyan Li, Christian Schulz, Elisabeth Kremmer, Steffen Massberg, Andreas Bültmann, and Meinrad Gawaz
Diabetes 2004 53: 2117 -2121. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear Factor-1 Genes Contribute to Glucose Intolerance in a South Indian Population

Alan E. Jackson, Paul G. Cassell, Bernard V. North, Shanti Vijayaraghavan, Susan V. Gelding, Ambady Ramachandran, Chamukuttan Snehalatha, and Graham A. Hitman
Diabetes 2004 53: 2122 -2125. [Abstract] [Full Text] [PDF]  

Variation at the Insulin Gene VNTR (Variable Number Tandem Repeat) Polymorphism and Early Growth: Studies in a Large Finnish Birth Cohort

Amanda J. Bennett, Ulla Sovio, Aimo Ruokonen, Hannu Martikainen, Anneli Pouta, Saara Taponen, Anna-Liisa Hartikainen, Vanessa J. King, Paul Elliott, Marjo-Riitta Järvelin, and Mark I. McCarthy
Diabetes 2004 53: 2126 -2131. [Abstract] [Full Text] [PDF]  

Adiponectin Receptor 1 Gene (ADIPOR1) as a Candidate for Type 2 Diabetes and Insulin Resistance

Hua Wang, Hailing Zhang, Yiwen Jia, Zhengxian Zhang, Rebekah Craig, Xiaoqin Wang, and Steven C. Elbein
Diabetes 2004 53: 2132 -2136. [Abstract] [Full Text] [PDF] Appendix  

Quantitative Trait Loci Near the Insulin-Degrading Enzyme (IDE) Gene Contribute to Variation in Plasma Insulin Levels

Harvest F. Gu, Suad Efendic, Sofia Nordman, Claes-Göran Östenson, Kerstin Brismar, Anthony J. Brookes, and Jonathan A. Prince
Diabetes 2004 53: 2137 -2142. [Abstract] [Full Text] [PDF]  

SREBF-1 Gene Polymorphisms Are Associated With Obesity and Type 2 Diabetes in French Obese and Diabetic Cohorts

Delphine Eberlé, Karine Clément, David Meyre, Mourad Sahbatou, Martine Vaxillaire, Annie Le Gall, Pascal Ferré, Arnaud Basdevant, Philippe Froguel, and Fabienne Foufelle
Diabetes 2004 53: 2153 -2157. [Abstract] [Full Text] [PDF] Appendix  

DPB1 Alleles Are Associated With Type 1 Diabetes Susceptibility in Multiple Ethnic Groups

Thomas D. Cruz, Ana M. Valdes, Alma Santiago, Teresa Frazer de Llado, Leslie J. Raffel, Adina Zeidler, Jerome I. Rotter, Henry A. Erlich, Marian Rewers, Teodorica Bugawan, and Janelle A. Noble
Diabetes 2004 53: 2158 -2163. [Abstract] [Full Text] [PDF]  

Severe Persistent Hyperinsulinemic Hypoglycemia due to a De Novo Glucokinase Mutation

Antonio L. Cuesta-Muñoz, Hanna Huopio, Timo Otonkoski, Juan M. Gomez-Zumaquero, Kirsti Näntö-Salonen, Jacques Rahier, Soledad López-Enriquez, Maria A. García-Gimeno, Pascual Sanz, Federico C. Soriguer, and Markku Laakso
Diabetes 2004 53: 2164 -2168. [Abstract] [Full Text] [PDF]  

Pharmacology & Therapeutics:

Effects of Rosiglitazone and Metformin on Liver Fat Content, Hepatic Insulin Resistance, Insulin Clearance, and Gene Expression in Adipose Tissue in Patients With Type 2 Diabetes

Mirja Tiikkainen, Anna-Maija Häkkinen, Elena Korsheninnikova, Tuulikki Nyman, Sari Mäkimattila, and Hannele Yki-Järvinen
Diabetes 2004 53: 2169 -2176. [Abstract] [Full Text] [PDF]  

Errata:

Errata

Diabetes 2004 53: 2177 . [Extract] [Full Text] [PDF]  

Errata

Diabetes 2004 53: 2177 . [Extract] [Full Text] [PDF]  

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