Diabetes -- Table of Contents (November 2005, 54 [11])

Perspectives in Diabetes:

Diabetes and Insulin Secretion: The ATP-Sensitive K⁺ Channel (K_ATP) Connection: Joseph C. Koster, M. Alan Permutt, and Colin G. Nichols
Diabetes 2005 54: 3065 -3072. [Abstract] [Full Text] [PDF]

Islet Studies:

Inositol (1,4,5)-Trisphosphate Dynamics and Intracellular Calcium Oscillations in Pancreatic ß-Cells: Natalia A. Tamarina, Andrey Kuznetsov, Christopher J. Rhodes, Vytautas P. Bindokas, and Louis H. Philipson
Diabetes 2005 54: 3073 -3081. [Abstract] [Full Text] [PDF]

Mechanisms of Glucose-Induced Secretion of Pancreatic-Derived Factor (PANDER or FAM3B) in Pancreatic ß-Cells: Jichun Yang, Claudia E. Robert, Brant R. Burkhardt, Robert A. Young, Jianmei Wu, Zhiyong Gao, and Bryan A. Wolf
Diabetes 2005 54: 3217 -3228. [Abstract] [Full Text] [PDF]

Restitution of Defective Glucose-Stimulated Insulin Secretion in Diabetic GK Rat by Acetylcholine Uncovers Paradoxical Stimulatory Effect of ß-Cell Muscarinic Receptor Activation on cAMP Production: Manuel Dolz, Danielle Bailbé, Marie-Hélène Giroix, Sophie Calderari, Marie-Noelle Gangnerau, Patricia Serradas, Katharina Rickenbach, Jean-Claude Irminger, and Bernard Portha
Diabetes 2005 54: 3229 -3237. [Abstract] [Full Text] [PDF]

Pathophysiology:

Effects of Diabetes on Ryanodine Receptor Ca Release Channel (RyR2) and Ca²⁺ Homeostasis in Rat Heart: Nazmi Yaras, Mehmet Ugur, Semir Ozdemir, Hakan Gurdal, Nuhan Purali, Alain Lacampagne, Guy Vassort, and Belma Turan
Diabetes 2005 54: 3082 -3088. [Abstract] [Full Text] [PDF]

Metallothionein-Mediated Antioxidant Defense System and Its Response to Exercise Training Are Impaired in Human Type 2 Diabetes: Celena Scheede-Bergdahl, Milena Penkowa, Juan Hidalgo, David B. Olsen, Peter Schjerling, Clara Prats, Robert Boushel, and Flemming Dela
Diabetes 2005 54: 3089 -3094. [Abstract] [Full Text] [PDF]

Is There a Role for Locally Produced Interleukin-1 in the Deleterious Effects of High Glucose or the Type 2 Diabetes Milieu to Human Pancreatic Islets?: Nils Welsh, Miriam Cnop, Ilham Kharroubi, Marco Bugliani, Roberto Lupi, Piero Marchetti, and Décio L. Eizirik
Diabetes 2005 54: 3238 -3244. [Abstract] [Full Text] [PDF]

Homocysteine Metabolism in ZDF (Type 2) Diabetic Rats: Enoka P. Wijekoon, Beatrice Hall, Shobhitha Ratnam, Margaret E. Brosnan, Steven H. Zeisel, and John T. Brosnan
Diabetes 2005 54: 3245 -3251. [Abstract] [Full Text] [PDF]

Insulin Resistance, the Metabolic Syndrome, and Incident Cardiovascular Events in the Framingham Offspring Study: Martin K. Rutter, James B. Meigs, Lisa M. Sullivan, Ralph B. D’Agostino, Sr, and Peter W. Wilson
Diabetes 2005 54: 3252 -3257. [Abstract] [Full Text] [PDF]

Celiac-Superior Mesenteric Ganglionectomy, but Not Vagotomy, Suppresses the Sympathoadrenal Response to Insulin-Induced Hypoglycemia: Satoshi Fujita and Casey M. Donovan
Diabetes 2005 54: 3258 -3264. [Abstract] [Full Text] [PDF]

Two-Hour Seven-Sample Oral Glucose Tolerance Test and Meal Protocol: Minimal Model Assessment of ß-Cell Responsivity and Insulin Sensitivity in Nondiabetic Individuals: Chiara Dalla Man, Marco Campioni, Kenneth S. Polonsky, Rita Basu, Robert A. Rizza, Gianna Toffolo, and Claudio Cobelli
Diabetes 2005 54: 3265 -3273. [Abstract] [Full Text] [PDF]

Complications:

The Human Glomerular Podocyte Is a Novel Target for Insulin Action: Richard J.M. Coward, Gavin I. Welsh, Jing Yang, Candida Tasman, Rachel Lennon, Ania Koziell, Simon Satchell, Geoffrey D. Holman, Dontscho Kerjaschki, Jeremy M. Tavaré, Peter W. Mathieson, and Moin A. Saleem
Diabetes 2005 54: 3095 -3102. [Abstract] [Full Text] [PDF]

Glycation and Carboxymethyllysine Levels in Skin Collagen Predict the Risk of Future 10-Year Progression of Diabetic Retinopathy and Nephropathy in the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications Participants With Type 1 Diabetes: Saul Genuth, Wanjie Sun, Patricia Cleary, David R. Sell, William Dahms, John Malone, William Sivitz, Vincent M. Monnier, and for the DCCT Skin Collagen Ancillary Study Group
Diabetes 2005 54: 3103 -3111. [Abstract] [Full Text] [PDF]

Noninvasive Monitoring of Diabetes-Induced Cutaneous Nerve Fiber Loss and Hypoalgesia in thy1-YFP Transgenic Mice: Yuk Shan Chen, Stephen S.M. Chung, and Sookja K. Chung
Diabetes 2005 54: 3112 -3118. [Abstract] [Full Text] [PDF] Online-Only Appendix

Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of db/db Mice: Alvin K.H. Cheung, Maggie K.L. Fung, Amy C.Y. Lo, Terence T.L. Lam, Kwok Fai So, Stephen S.M. Chung, and Sookja K. Chung
Diabetes 2005 54: 3119 -3125. [Abstract] [Full Text] [PDF]

Susceptibility to Diabetic Nephropathy Is Related to Dicarbonyl and Oxidative Stress: Paul J. Beisswenger, Keith S. Drummond, Robert G. Nelson, Scott K. Howell, Benjamin S. Szwergold, and Michael Mauer
Diabetes 2005 54: 3274 -3281. [Abstract] [Full Text] [PDF]

Reduced Nitric Oxide Concentration in the Renal Cortex of Streptozotocin-Induced Diabetic Rats: Effects on Renal Oxygenation and Microcirculation: Fredrik Palm, Donald G. Buerk, Per-Ola Carlsson, Peter Hansell, and Per Liss
Diabetes 2005 54: 3282 -3287. [Abstract] [Full Text] [PDF]

Apoptotic Stress Is Counterbalanced by Survival Elements Preventing Programmed Cell Death of Dorsal Root Ganglions in Subacute Type 1 Diabetic BB/Wor Rats: Hideki Kamiya, Weixian Zhangm, and Anders A.F. Sima
Diabetes 2005 54: 3288 -3295. [Abstract] [Full Text] [PDF]

Genetics:

Large Genomic Rearrangements in the Hepatocyte Nuclear Factor-1ß (TCF2) Gene Are the Most Frequent Cause of Maturity-Onset Diabetes of the Young Type 5: Christine Bellanné-Chantelot, Séverine Clauin, Dominique Chauveau, Philippe Collin, Michèle Daumont, Claire Douillard, Danièle Dubois-Laforgue, Laurent Dusselier, Jean-François Gautier, Michel Jadoul, Marie Laloi-Michelin, Laetitia Jacquesson, Etienne Larger, Jacques Louis, Marc Nicolino, Jean-François Subra, Jean-Marie Wilhem, Jacques Young, Gilberto Velho, and José Timsit
Diabetes 2005 54: 3126 -3132. [Abstract] [Full Text] [PDF] Online-Only Appendix

Protein Tyrosine Phosphatase-1B Gene PTPN1: Selection of Tagging Single Nucleotide Polymorphisms and Association With Body Fat, Insulin Sensitivity, and the Metabolic Syndrome in a Normal Female Population: Nicola J. Spencer-Jones, Xiaoling Wang, Harold Snieder, Tim D. Spector, Nicholas D. Carter, and Sandra D. O’Dell
Diabetes 2005 54: 3296 -3304. [Abstract] [Full Text] [PDF] Online-Only Supplement

Assessment of 115 Candidate Genes for Diabetic Nephropathy by Transmission/Disequilibrium Test: Kathryn Gogolin Ewens, Roberta Ann George, Kumar Sharma, Fuad N. Ziyadeh, and Richard S. Spielman
Diabetes 2005 54: 3305 -3318. [Abstract] [Full Text] [PDF] Online-Only Appendix

Sequence Variation in PPARG May Underlie Differential Response to Troglitazone: Johanna K. Wolford, Kimberly A. Yeatts, Sharanjeet K. Dhanjal, Mary Helen Black, Anny H. Xiang, Thomas A. Buchanan, and Richard M. Watanabe
Diabetes 2005 54: 3319 -3325. [Abstract] [Full Text] [PDF]

Metabolism:

Partial Gene Deletion of Heart-Type Fatty Acid–Binding Protein Limits the Severity of Dietary-Induced Insulin Resistance: Jane Shearer, Patrick T. Fueger, Deanna P. Bracy, David H. Wasserman, and Jeffrey N. Rottman
Diabetes 2005 54: 3133 -3139. [Abstract] [Full Text] [PDF]

Liver Markers and Development of the Metabolic Syndrome: The Insulin Resistance Atherosclerosis Study: Anthony J.G. Hanley, Ken Williams, Andreas Festa, Lynne E. Wagenknecht, Ralph B. D’Agostino, Jr, and Steven M. Haffner
Diabetes 2005 54: 3140 -3147. [Abstract] [Full Text] [PDF]

Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic Patients: Mandeep Bajaj, Swangjit Suraamornkul, Anthony Romanelli, Gary W. Cline, Lawrence J. Mandarino, Gerald I. Shulman, and Ralph A. DeFronzo
Diabetes 2005 54: 3148 -3153. [Abstract] [Full Text] [PDF]

The Stimulatory Effect of Globular Adiponectin on Insulin-Stimulated Glucose Uptake and Fatty Acid Oxidation Is Impaired in Skeletal Muscle From Obese Subjects: Clinton R. Bruce, Valerie A. Mertz, George J.F. Heigenhauser, and David J. Dyck
Diabetes 2005 54: 3154 -3160. [Abstract] [Full Text] [PDF]

Signal Transduction:

Insulin-Stimulated Glucose Uptake Does Not Require p38 Mitogen-Activated Protein Kinase in Adipose Tissue or Skeletal Muscle: Sophie Turban, Victoria A. Beardmore, Julia M. Carr, Kei Sakamoto, Eric Hajduch, J. Simon C. Arthur, and Harinder S. Hundal
Diabetes 2005 54: 3161 -3168. [Abstract] [Full Text] [PDF]

Activation of ATP-Sensitive K⁺ Channels in the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses to Hypoglycemia in Normal and Recurrently Hypoglycemic Rats: Rory J. McCrimmon, Mark L. Evans, Xiaoning Fan, Ewan C. McNay, Owen Chan, Yuyan Ding, Wanling Zhu, Dorte X. Gram, and Robert S. Sherwin
Diabetes 2005 54: 3169 -3174. [Abstract] [Full Text] [PDF]

Impaired Generation of Reactive Oxygen Species in Leprechaunism Through Downregulation of Nox4: Hye Sun Park, Dong Kyu Jin, Sang Min Shin, Mi Kyung Jang, Nicholas Longo, Ji Won Park, Duk Soo Bae, and Yun Soo Bae
Diabetes 2005 54: 3175 -3181. [Abstract] [Full Text] [PDF]

Obesity Studies:

Central Leptin Acutely Reverses Diet-Induced Hepatic Insulin Resistance: Alessandro Pocai, Kimyata Morgan, Christoph Buettner, Roger Gutierrez-Juarez, Silvana Obici, and Luciano Rossetti
Diabetes 2005 54: 3182 -3189. [Abstract] [Full Text] [PDF]

Adipocyte Lipases and Defect of Lipolysis in Human Obesity: Dominique Langin, Andrea Dicker, Geneviève Tavernier, Johan Hoffstedt, Aline Mairal, Mikael Rydén, Erik Arner, Audrey Sicard, Christopher M. Jenkins, Nathalie Viguerie, Vanessa van Harmelen, Richard W. Gross, Cecilia Holm, and Peter Arner
Diabetes 2005 54: 3190 -3197. [Abstract] [Full Text] [PDF] Online-Only Appendix

Peptide YY_(3–36) Inhibits Morning, but Not Evening, Food Intake and Decreases Body Weight in Rhesus Macaques: Frank H. Koegler, Pablo J. Enriori, Sonja K. Billes, Diana L. Takahashi, Meghan S. Martin, Randall L. Clark, Anne E. Evans, Kevin L. Grove, Judy L. Cameron, and Michael A. Cowley
Diabetes 2005 54: 3198 -3204. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Islet Cell Hormonal Responses to Hypoglycemia After Human Islet Transplantation for Type 1 Diabetes: Michael R. Rickels, Mark H. Schutta, Rebecca Mueller, James F. Markmann, Clyde F. Barker, Ali Naji, and Karen L. Teff
Diabetes 2005 54: 3205 -3211. [Abstract] [Full Text] [PDF]

Exposure to Farming Environments in Early Life and Type 1 Diabetes: A Case-Control Study: Katja Radon, Doris Windstetter, Susanne Solfrank, Erika von Mutius, Dennis Nowak, Hans-Peter Schwarz, and for the Chronic Autoimmune Disease and Contact to Animals (CAT) Study Group
Diabetes 2005 54: 3212 -3216. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

The Fatty Acid–Binding Protein-2 A54T Polymorphism Is Associated With Renal Disease in Patients With Type 2 Diabetes: Luis H. Canani, Clarissa Capp, Daniel P.K. Ng, Serena G.L. Choo, Ana Luiza Maia, Gustavo B. Nabinger, Kátia Santos, Daisy Crispim, Israel Roisemberg, Andrzej S. Krolewski, and Jorge L. Gross
Diabetes 2005 54: 3326 -3330. [Abstract] [Full Text] [PDF]

Risk of Diabetic Nephropathy in Type 1 Diabetes Is Associated With Functional Polymorphisms in RANTES Receptor Gene (CCR5): A Sex-Specific Effect: Wojciech M. Mlynarski, Grzegorz P. Placha, Pawel P. Wolkow, Jacek P. Bochenski, James H. Warram, and Andrzej S. Krolewski
Diabetes 2005 54: 3331 -3335. [Abstract] [Full Text] [PDF]

Altered Calcium Homeostasis Is Correlated With Abnormalities of Fasting Serum Glucose, Insulin Resistance, and ß-Cell Function in the Newfoundland Population: Guang Sun, Sudesh Vasdev, Glynn R. Martin, Veeresh Gadag, and Hongwei Zhang
Diabetes 2005 54: 3336 -3339. [Abstract] [Full Text] [PDF]

Errata:

Erratum: Diabetes 2005 54: 3340 . [Extract] [Full Text] [PDF]