Rapid Publications:

Retinoic Acid Induces Pdx1-Positive Endoderm in Differentiating Mouse Embryonic Stem Cells

Suzanne J. Micallef, Mary E. Janes, Kathy Knezevic, Richard P. Davis, Andrew G. Elefanty, and Edouard G. Stanley
Diabetes 2005 54: 301 -305. First published on December 7, 2004 as 10.2337/diabetes.54.2.301 [Abstract] [Full Text] [PDF]  

Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes

Elmar Jaeckel, Harald von Boehmer, and Michael P. Manns
Diabetes 2005 54: 306 -310. First published on December 10, 2004 as 10.2337/diabetes.54.2.306 [Abstract] [Full Text] [PDF] Appendix  

Perspective in Diabetes:

Redox Paradox: Insulin Action Is Facilitated by Insulin-Stimulated Reactive Oxygen Species With Multiple Potential Signaling Targets

Barry J. Goldstein, Kalyankar Mahadev, and Xiangdong Wu
Diabetes 2005 54: 311 -321. [Abstract] [Full Text] [PDF]  

Dissipating Excess Energy Stored in the Liver Is a Potential Treatment Strategy for Diabetes Associated With Obesity

Yasushi Ishigaki, Hideki Katagiri, Tetsuya Yamada, Takehide Ogihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Tooru Shimosegawa, Hideyuki Sakoda, Tomoichiro Asano, and Yoshitomo Oka
Diabetes 2005 54: 322 -332. [Abstract] [Full Text] [PDF]  

Identification of Individuals With Insulin Resistance Using Routine Clinical Measurements

Steven E. Stern, Ken Williams, Eleuterio Ferrannini, Ralph A. DeFronzo, Clifton Bogardus, and Michael P. Stern
Diabetes 2005 54: 333 -339. [Abstract] [Full Text] [PDF] Appendix  

A Reduced-Fat Diet and Aerobic Exercise in Japanese Americans With Impaired Glucose Tolerance Decreases Intra-Abdominal Fat and Improves Insulin Sensitivity but not ß-Cell Function

Darcy B. Carr, Kristina M. Utzschneider, Edward J. Boyko, Pamela J. Asberry, Rebecca L. Hull, Keiichi Kodama, Holly S. Callahan, Colleen C. Matthys, Donna L. Leonetti, Robert S. Schwartz, Steven E. Kahn, and Wilfred Y. Fujimoto
Diabetes 2005 54: 340 -347. [Abstract] [Full Text] [PDF]  

Signal Transduction:

Luminal Leptin Induces Rapid Inhibition of Active Intestinal Absorption of Glucose Mediated by Sodium-Glucose Cotransporter 1

Robert Ducroc, Sandra Guilmeau, Khalil Akasbi, Hélène Devaud, Marion Buyse, and André Bado
Diabetes 2005 54: 348 -354. [Abstract] [Full Text] [PDF]  

5-Aminoimidazole-4-Carboxamide-1-ß-D-Ribofuranoside Causes Acute Hepatic Insulin Resistance In Vivo

R. Richard Pencek, Jane Shearer, Raul C. Camacho, Freyja D. James, D. Brooks Lacy, Patrick T. Fueger, E. Patrick Donahue, Wanda Snead, and David H. Wasserman
Diabetes 2005 54: 355 -360. [Abstract] [Full Text] [PDF]  

Insulin Glulisine: Insulin Receptor Signaling Characteristics In Vivo

Anita M. Hennige, Rainer Lehmann, Cora Weigert, Klaus Moeschel, Myriam Schäuble, Elisabeth Metzinger, Reiner Lammers, and Hans-Ulrich Häring
Diabetes 2005 54: 361 -366. [Abstract] [Full Text] [PDF]  

Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance

Hengjiang Dong, Betty A. Maddux, Jennifer Altomonte, Marcia Meseck, Domenico Accili, Robert Terkeltaub, Kristen Johnson, Jack F. Youngren, and Ira D. Goldfine
Diabetes 2005 54: 367 -372. [Abstract] [Full Text] [PDF]  

Portal Venous 5-Aminoimidazole-4-Carboxamide-1-ß-D-Ribofuranoside Infusion Overcomes Hyperinsulinemic Suppression of Endogenous Glucose Output

Raul C. Camacho, R. Richard Pencek, D. Brooks Lacy, Freyja D. James, E. Patrick Donahue, and David H. Wasserman
Diabetes 2005 54: 373 -382. [Abstract] [Full Text] [PDF]  

High Glucose Regulates the Activity of Cardiac Sarcolemmal ATP-Sensitive K⁺ Channels via 1,3-Bisphosphoglycerate: A Novel Link Between Cardiac Membrane Excitability and Glucose Metabolism

Sofija Jovanovic and Aleksandar Jovanovic
Diabetes 2005 54: 383 -393. [Abstract] [Full Text] [PDF]  

Hyperglycemia Activates JAK2 Signaling Pathway in Human Failing Myocytes via Angiotensin II–Mediated Oxidative Stress

Alessandra Modesti, Iacopo Bertolozzi, Tania Gamberi, Matilde Marchetta, Camilla Lumachi, Mirella Coppo, Federico Moroni, Thomas Toscano, Gianluca Lucchese, Gian F. Gensini, and Pietro A. Modesti
Diabetes 2005 54: 394 -401. [Abstract] [Full Text] [PDF]  

Obesity Studies:

The Extracellular Signal–Regulated Kinase Isoform ERK1 Is Specifically Required for In Vitro and In Vivo Adipogenesis

Frédéric Bost, Myriam Aouadi, Leslie Caron, Patrick Even, Nathalie Belmonte, Matthieu Prot, Christian Dani, Paul Hofman, Gilles Pagès, Jacques Pouysségur, Yannick Le Marchand-Brustel, and Bernard Binétruy
Diabetes 2005 54: 402 -411. [Abstract] [Full Text] [PDF]  

Interaction of Fish Oil and Conjugated Linoleic Acid in Affecting Hepatic Activity of Lipogenic Enzymes and Gene Expression in Liver and Adipose Tissue

Takashi Ide
Diabetes 2005 54: 412 -423. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Adenovirus-Mediated XIAP Gene Transfer Reverses the Negative Effects of Immunosuppressive Drugs on Insulin Secretion and Cell Viability of Isolated Human Islets

Hongxiang Hui, Nasif Khoury, Xiaoning Zhao, Levent Balkir, Eugenio D’Amico, Angela Bullotta, Elizabeth D. Nguyen, Andrea Gambotto, and Riccardo Perfetti
Diabetes 2005 54: 424 -433. [Abstract] [Full Text] [PDF]  

Autoimmune Diabetes Is Suppressed by Transfer of Proinsulin-Encoding Gr-1⁺ Myeloid Progenitor Cells That Differentiate In Vivo Into Resting Dendritic Cells

Raymond J. Steptoe, Janine M. Ritchie, Lynelle K. Jones, and Leonard C. Harrison
Diabetes 2005 54: 434 -442. [Abstract] [Full Text] [PDF] Appendix  

Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB

Gina R. Rayat and Ronald G. Gill
Diabetes 2005 54: 443 -451. [Abstract] [Full Text] [PDF]  

Islet Studies:

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca²⁺ ATPase 2b and Deplete Endoplasmic Reticulum Ca²⁺, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic ß-Cells

Alessandra K. Cardozo, Fernanda Ortis, Joachim Storling, Ying-Mei Feng, Joanne Rasschaert, Morten Tonnesen, Françoise Van Eylen, Thomas Mandrup-Poulsen, André Herchuelz, and Décio L. Eizirik
Diabetes 2005 54: 452 -461. [Abstract] [Full Text] [PDF]  

Alteration of the Malonyl-CoA/Carnitine Palmitoyltransferase I Interaction in the ß-Cell Impairs Glucose-Induced Insulin Secretion

Laura Herrero, Blanca Rubí, David Sebastián, Dolors Serra, Guillermina Asins, Pierre Maechler, Marc Prentki, and Fausto G. Hegardt
Diabetes 2005 54: 462 -471. [Abstract] [Full Text] [PDF]  

Fatty Acid Translocase (FAT/CD36) Is Localized on Insulin-Containing Granules in Human Pancreatic ß-Cells and Mediates Fatty Acid Effects on Insulin Secretion

Houtan Noushmehr, Eugenio D’Amico, Loredana Farilla, Hongxiang Hui, Kolja A. Wawrowsky, Wojciech Mlynarski, Alessandro Doria, Nada A. Abumrad, and Riccardo Perfetti
Diabetes 2005 54: 472 -481. [Abstract] [Full Text] [PDF]  

ß-Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1

Yazhou Li, Xiemin Cao, Li-Xin Li, Patricia L. Brubaker, Helena Edlund, and Daniel J. Drucker
Diabetes 2005 54: 482 -491. [Abstract] [Full Text] [PDF]  

Transgenic Mice Overexpressing Nuclear SREBP-1c in Pancreatic ß-Cells

Akimitsu Takahashi, Kaori Motomura, Toyonori Kato, Tomohiro Yoshikawa, Yoshimi Nakagawa, Naoya Yahagi, Hirohito Sone, Hiroaki Suzuki, Hideo Toyoshima, Nobuhiro Yamada, and Hitoshi Shimano
Diabetes 2005 54: 492 -499. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Hypoglycemia Induces Transient Neurogenesis and Subsequent Progenitor Cell Loss in the Rat Hippocampus

Sang Won Suh, Yang Fan, Shwuhuey M. Hong, Zhengyan Liu, Yasuhiko Matsumori, Philip R. Weinstein, Raymond A. Swanson, and Jialing Liu
Diabetes 2005 54: 500 -509. [Abstract] [Full Text] [PDF]  

Bumetanide Reduces Cerebral Edema Formation in Rats With Diabetic Ketoacidosis

Tina I. Lam, Steven E. Anderson, Nicole Glaser, and Martha E. O’Donnell
Diabetes 2005 54: 510 -516. [Abstract] [Full Text] [PDF]  

Complications:

Paradoxical Effects of Green Tea (Camellia Sinensis) and Antioxidant Vitamins in Diabetic Rats: Improved Retinopathy and Renal Mitochondrial Defects but Deterioration of Collagen Matrix Glycoxidation and Cross-Linking

Georgian T. Mustata, Mariana Rosca, Klaus M. Biemel, Oliver Reihl, Mark A. Smith, Ashwini Viswanathan, Christopher Strauch, Yunpeng Du, Jie Tang, Timothy S. Kern, Markus O. Lederer, Michael Brownlee, Miriam F. Weiss, and Vincent M. Monnier
Diabetes 2005 54: 517 -526. [Abstract] [Full Text] [PDF]  

The Relationship of Diabetic Retinopathy to Preclinical Diabetic Glomerulopathy Lesions in Type 1 Diabetic Patients: The Renin-Angiotensin System Study

Ronald Klein, Bernard Zinman, Robert Gardiner, Samy Suissa, Sandra M. Donnelly, Alan R. Sinaiko, Michael S. Kramer, Paul Goodyer, Scot E. Moss, Trudy Strand, and Michael Mauer
Diabetes 2005 54: 527 -533. [Abstract] [Full Text] [PDF]  

Adiponectin and Future Coronary Heart Disease Events Among Men With Type 2 Diabetes

Matthias B. Schulze, Iris Shai, Eric B. Rimm, Tricia Li, Nader Rifai, and Frank B. Hu
Diabetes 2005 54: 534 -539. [Abstract] [Full Text] [PDF]  

High Glucose Inhibits Apoptosis Induced by Serum Deprivation in Vascular Smooth Muscle Cells via Upregulation of Bcl-2 and Bcl-xl

Haikun Li, Sabine Télémaque, Richard E. Miller, and James D. Marsh
Diabetes 2005 54: 540 -545. [Abstract] [Full Text] [PDF]  

Folic Acid Supplementation Diminishes Diabetes- and Glucose-Induced Dysmorphogenesis in Rat Embryos In Vivo and In Vitro

Parri Wentzel, Mattias Gäreskog, and Ulf J. Eriksson
Diabetes 2005 54: 546 -553. [Abstract] [Full Text] [PDF]  

Pharmacology and Therapeutics:

Rosiglitazone Treatment in Zucker Diabetic Fatty Rats Is Associated With Ameliorated Cardiac Insulin Resistance and Protection From Ischemia/Reperfusion-Induced Myocardial Injury

Tian-Li Yue, Weike Bao, Juan-Li Gu, Jianqi Cui, Ling Tao, Xin-Liang Ma, Eliot H. Ohlstein, and Beat M. Jucker
Diabetes 2005 54: 554 -562. [Abstract] [Full Text] [PDF]  

Cumulative Incidence of Type 1 Diabetes in 10,168 Siblings of Finnish Young-Onset Type 1 Diabetic Patients

Valma Harjutsalo, Toomas Podar, and Jaakko Tuomilehto
Diabetes 2005 54: 563 -569. [Abstract] [Full Text] [PDF]  

Complement C3 Is a Risk Factor for the Development of Diabetes: A Population-Based Cohort Study

Gunnar Engström, Bo Hedblad, Karl-Fredrik Eriksson, Lars Janzon, and Folke Lindgärde
Diabetes 2005 54: 570 -575. [Abstract] [Full Text] [PDF]  

Genetic Regulation of Birth Weight and Fasting Glucose by a Common Polymorphism in the Islet Cell Promoter of the Glucokinase Gene

Michael N. Weedon, Timothy M. Frayling, Beverley Shields, Beatrice Knight, Tina Turner, Bradley S. Metcalf, Linda Voss, Terence J. Wilkin, Anne McCarthy, Yoav Ben-Shlomo, George Davey Smith, Sue Ring, Richard Jones, Jean Golding, ALSPAC Study Team, Liisa Byberg, Vera Mann, Tomas Axelsson, Ann-Christine Syvänen, David Leon, and Andrew T. Hattersley
Diabetes 2005 54: 576 -581. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

Peroxisome Proliferator-Activated Receptor Gene Variation Influences Age of Onset and Progression of Type 2 Diabetes

David M. Flavell, Helen Ireland, Jeffrey W. Stephens, Emma Hawe, Jay Acharya, Hugh Mather, Steven J. Hurel, and Steve E. Humphries
Diabetes 2005 54: 582 -586. [Abstract] [Full Text] [PDF]  

Errata:

Errata

Diabetes 2005 54: 587 . [Extract] [Full Text] [PDF]  

Errata

Diabetes 2005 54: 587 . [Extract] [Full Text] [PDF]  

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