Diabetes -- Table of Contents (March 2005, 54 [3])

Perspectives in Diabetes:

A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome: Scott A. Summers and Don H. Nelson
Diabetes 2005 54: 591 -602. [Abstract] [Full Text] [PDF]

Metabolism:

Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes: Kitt Falk Petersen, Sylvie Dufour, Douglas Befroy, Michael Lehrke, Rosa E. Hendler, and Gerald I. Shulman
Diabetes 2005 54: 603 -608. [Abstract] [Full Text] [PDF]

Fructose Normalizes Specific Counterregulatory Responses to Hypoglycemia in Patients With Type 1 Diabetes: Ilan Gabriely and Harry Shamoon
Diabetes 2005 54: 609 -616. [Abstract] [Full Text] [PDF]

Increased Potency and Efficacy of Combined Phosphorylase Inactivation and Glucokinase Activation in Control of Hepatocyte Glycogen Metabolism: Laura J. Hampson and Loranne Agius
Diabetes 2005 54: 617 -623. [Abstract] [Full Text] [PDF]

Calcineurin Does Not Mediate Exercise-Induced Increase in Muscle GLUT4: Pablo M. Garcia-Roves, Terry E. Jones, Kenichi Otani, Dong-Ho Han, and John O. Holloszy
Diabetes 2005 54: 624 -628. [Abstract] [Full Text] [PDF]

Free Fatty Acid Regulation of Glucose-Dependent Intrinsic Oscillatory Lipolysis in Perifused Isolated Rat Adipocytes: Lisa Getty-Kaushik, Ann-Marie T. Richard, and Barbara E. Corkey
Diabetes 2005 54: 629 -637. [Abstract] [Full Text] [PDF]

Munc18c Heterozygous Knockout Mice Display Increased Susceptibility for Severe Glucose Intolerance: Eunjin Oh, Beth A. Spurlin, Jeffrey E. Pessin, and Debbie C. Thurmond
Diabetes 2005 54: 638 -647. [Abstract] [Full Text] [PDF]

Differential Utilization of Saturated Palmitate and Unsaturated Oleate: Evidence From Cultured Myotubes: Michael Gaster, Arild C. Rustan, and Henning Beck-Nielsen
Diabetes 2005 54: 648 -656. [Abstract] [Full Text] [PDF]

Signal Transduction:

The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes: Kentaro Ozawa, Mayuki Miyazaki, Munehide Matsuhisa, Katsura Takano, Yoshihisa Nakatani, Masahiro Hatazaki, Takashi Tamatani, Kazuya Yamagata, Jun-ichiro Miyagawa, Yasuko Kitao, Osamu Hori, Yoshimitsu Yamasaki, and Satoshi Ogawa
Diabetes 2005 54: 657 -663. [Abstract] [Full Text] [PDF] Appendix

Obesity Studies:

Apolipoprotein C3 Deficiency Results in Diet-Induced Obesity and Aggravated Insulin Resistance in Mice: Ilse Duivenvoorden, Bas Teusink, Patrick C. Rensen, Johannes A. Romijn, Louis M. Havekes, and Peter J. Voshol
Diabetes 2005 54: 664 -671. [Abstract] [Full Text] [PDF]

Differential Responses of Visceral and Subcutaneous Fat Depots to Nutrients: Francine H. Einstein, Gil Atzmon, Xiao-man Yang, Xiao-Hui Ma, Marielisa Rincon, Eric Rudin, Radhika Muzumdar, and Nir Barzilai
Diabetes 2005 54: 672 -678. [Abstract] [Full Text] [PDF]

Caveolin-1 Expression Is Essential for Proper Nonshivering Thermogenesis in Brown Adipose Tissue: Alex W. Cohen, William Schubert, Dawn L. Brasaemle, Philipp E. Scherer, and Michael P. Lisanti
Diabetes 2005 54: 679 -686. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Long-Term Graft Function of Adult Rat and Human Islets Encapsulated in Novel Alginate-Based Microcapsules After Transplantation in Immunocompetent Diabetic Mice: Stephan Schneider, Peter J. Feilen, Frank Brunnenmeier, Timo Minnemann, Heiko Zimmermann, Ulrich Zimmermann, and Matthias M. Weber
Diabetes 2005 54: 687 -693. [Abstract] [Full Text] [PDF]

Islet Studies:

Matrix Metalloproteinases 2 and 9 Are Dispensable for Pancreatic Islet Formation and Function In Vivo: Sabina E. Perez, David A. Cano, Trang Dao-Pick, Jean-Phillipe Rougier, Zena Werb, and Matthias Hebrok
Diabetes 2005 54: 694 -701. [Abstract] [Full Text] [PDF] Appendix

ß-Cell Secretory Dysfunction in the Pathogenesis of Low Birth Weight–Associated Diabetes: A Murine Model: Josep C. Jimenez-Chillaron, Marcelino Hernandez-Valencia, Carolyn Reamer, Simon Fisher, Allison Joszi, Michael Hirshman, Aysin Oge, Shana Walrond, Roberta Przybyla, Carol Boozer, Laurie J. Goodyear, and Mary-Elizabeth Patti
Diabetes 2005 54: 702 -711. [Abstract] [Full Text] [PDF]

Overexpression of Cyclin D1 in Pancreatic ß-Cells In Vivo Results in Islet Hyperplasia Without Hypoglycemia: Xiaoboo Zhang, John P. Gaspard, Yusuke Mizukami, Jingnan Li, Fiona Graeme-Cook, and Daniel C. Chung
Diabetes 2005 54: 712 -719. [Abstract] [Full Text] [PDF]

TAT-Mediated Neurogenin 3 Protein Transduction Stimulates Pancreatic Endocrine Differentiation In Vitro: Juan Domínguez-Bendala, Dagmar Klein, Melina Ribeiro, Camillo Ricordi, Luca Inverardi, Ricardo Pastori, and Helena Edlund
Diabetes 2005 54: 720 -726. [Abstract] [Full Text] [PDF] Appendix

Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes: Silvia Del Guerra, Roberto Lupi, Lorella Marselli, Matilde Masini, Marco Bugliani, Simone Sbrana, Scilla Torri, Maria Pollera, Ugo Boggi, Franco Mosca, Stefano Del Prato, and Piero Marchetti
Diabetes 2005 54: 727 -735. [Abstract] [Full Text] [PDF]

Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat ß-Cells: Patrick E. MacDonald, Stefanie Obermüller, Jenny Vikman, Juris Galvanovskis, Patrik Rorsman, and Lena Eliasson
Diabetes 2005 54: 736 -743. [Abstract] [Full Text] [PDF]

Pathophysiology:

Effects of Sustained Insulin-Induced Hypoglycemia on Cardiovascular Autonomic Regulation in Type 1 Diabetes: Minna L. Koivikko, Pasi I. Salmela, K.E. Juhani Airaksinen, Juha S. Tapanainen, Aimo Ruokonen, Timo H. Mäkikallio, and Heikki V. Huikuri
Diabetes 2005 54: 744 -750. [Abstract] [Full Text] [PDF]

Redistribution of Glucose From Skeletal Muscle to Adipose Tissue During Catch-Up Fat: A Link Between Catch-Up Growth and Later Metabolic Syndrome: Philippe Cettour-Rose, Sonia Samec, Aaron P. Russell, Serge Summermatter, Davide Mainieri, Claudia Carrillo-Theander, Jean-Pierre Montani, Josiane Seydoux, Françoise Rohner-Jeanrenaud, and Abdul G. Dulloo
Diabetes 2005 54: 751 -756. [Abstract] [Full Text] [PDF]

Loss of the Decrement in Intraislet Insulin Plausibly Explains Loss of the Glucagon Response to Hypoglycemia in Insulin-Deficient Diabetes: Documentation of the Intraislet Insulin Hypothesis in Humans: Bharathi Raju and Philip E. Cryer
Diabetes 2005 54: 757 -764. [Abstract] [Full Text] [PDF]

Effect of Dehydroepiandrosterone Replacement on Insulin Sensitivity and Lipids in Hypoadrenal Women: Ketan Dhatariya, Maureen L. Bigelow, and K. Sreekumaran Nair
Diabetes 2005 54: 765 -769. [Abstract] [Full Text] [PDF]

Contribution of Abdominal Visceral Obesity and Insulin Resistance to the Cardiovascular Risk Profile of Postmenopausal Women: Marie-Ève Piché, S. John Weisnagel, Louise Corneau, André Nadeau, Jean Bergeron, and Simone Lemieux
Diabetes 2005 54: 770 -777. [Abstract] [Full Text] [PDF]

Absence of Heme Oxygenase-1 Exacerbates Myocardial Ischemia/Reperfusion Injury in Diabetic Mice: Xiaoli Liu, Jiao Wei, David H. Peng, Matthew D. Layne, and Shaw-Fang Yet
Diabetes 2005 54: 778 -784. [Abstract] [Full Text] [PDF]

Complications:

Impaired Retinal Angiogenesis in Diabetes: Role of Advanced Glycation End Products and Galectin-3: Alan W. Stitt, Ciara McGoldrick, Aine Rice-McCaldin, David R. McCance, Josephine V. Glenn, Daniel K. Hsu, Fu-Tong Liu, Suzanne R. Thorpe, and Tom A. Gardiner
Diabetes 2005 54: 785 -794. [Abstract] [Full Text] [PDF]

Adipocytokines and VLDL Metabolism: Independent Regulatory Effects of Adiponectin, Insulin Resistance, and Fat Compartments on VLDL Apolipoprotein B-100 Kinetics?: Theodore W.K. Ng, Gerald F. Watts, Maryam S. Farvid, Dick C. Chan, and P. Hugh R. Barrett
Diabetes 2005 54: 795 -802. [Abstract] [Full Text] [PDF]

Hyperglycemia in Streptozotocin-Induced Diabetic Rat Increases Infarct Size Associated With Low Levels of Myocardial HO-1 During Ischemia/Reperfusion: Clara Di Filippo, Raffaele Marfella, Salvatore Cuzzocrea, Elena Piegari, Pasquale Petronella, Dario Giugliano, Francesco Rossi, and Michele D’Amico
Diabetes 2005 54: 803 -810. [Abstract] [Full Text] [PDF]

Pioglitazone Induces Vascular Smooth Muscle Cell Apoptosis Through a Peroxisome Proliferator-Activated Receptor- ${gamma}$ , Transforming Growth Factor-ß1, and a Smad2-Dependent Mechanism: Santiago Redondo, Emilio Ruiz, Carlos G. Santos-Gallego, Eugenia Padilla, and Teresa Tejerina
Diabetes 2005 54: 811 -817. [Abstract] [Full Text] [PDF]

Requirement of Aldose Reductase for the Hyperglycemic Activation of Protein Kinase C and Formation of Diacylglycerol in Vascular Smooth Muscle Cells: Kota V. Ramana, Brian Friedrich, Ravinder Tammali, Matthew B. West, Aruni Bhatnagar, and Satish K. Srivastava
Diabetes 2005 54: 818 -829. [Abstract] [Full Text] [PDF]

Experimental Diabetic Neuropathy With Spontaneous Recovery: Is There Irreparable Damage?: James M. Kennedy and Douglas W. Zochodne
Diabetes 2005 54: 830 -837. [Abstract] [Full Text] [PDF]

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Prevents Renal Insufficiency and Mesangial Matrix Expansion in Diabetic db/db Mice: Kazuyuki Shibuya, Keizo Kanasaki, Motohide Isono, Haruhisa Sato, Mitsugu Omata, Toshiro Sugimoto, Shin-ichi Araki, Keiji Isshiki, Atsunori Kashiwagi, Masakazu Haneda, and Daisuke Koya
Diabetes 2005 54: 838 -845. [Abstract] [Full Text] [PDF]

Nonviral Gene Transfer of Human Hepatocyte Growth Factor Improves Streptozotocin-Induced Diabetic Neuropathy in Rats: Naoki Kato, Koichi Nemoto, Kuniaki Nakanishi, Ryuichi Morishita, Yasufumi Kaneda, Maki Uenoyama, Tomosumi Ikeda, and Kyosuke Fujikawa
Diabetes 2005 54: 846 -854. [Abstract] [Full Text] [PDF]

Topical Pretreatment of Diabetic Rats With All-trans Retinoic Acid Improves Healing of Subsequently Induced Abrasion Wounds: Humaira Lateef, Omorodola I. Abatan, Muhammad Nadeem Aslam, Martin J. Stevens, and James Varani
Diabetes 2005 54: 855 -861. [Abstract] [Full Text] [PDF]

Pharmacology and Therapeutics:

Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs: Marilyn Ader, Stella P. Kim, Karyn J. Catalano, Viorica Ionut, Katrin Hucking, Joyce M. Richey, Morvarid Kabir, and Richard N. Bergman
Diabetes 2005 54: 862 -871. [Abstract] [Full Text] [PDF]

Increased In Vivo Regeneration of Cortisol in Adipose Tissue in Human Obesity and Effects of the 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Carbenoxolone: Thekkepat C. Sandeep, Ruth Andrew, Natalie Z.M. Homer, Robert C. Andrews, Ken Smith, and Brian R. Walker
Diabetes 2005 54: 872 -879. [Abstract] [Full Text] [PDF]

Thiazolidinediones Upregulate Fatty Acid Uptake and Oxidation in Adipose Tissue of Diabetic Patients: Guenther Boden, Carol Homko, Maria Mozzoli, Louise C. Showe, Calen Nichols, and Peter Cheung
Diabetes 2005 54: 880 -885. [Abstract] [Full Text] [PDF] Appendix

Genetics:

Association Testing of Variants in the Hepatocyte Nuclear Factor 4 ${alpha}$ Gene With Risk of Type 2 Diabetes in 7,883 People: Wendy Winckler, Robert R. Graham, Paul I.W. de Bakker, Maria Sun, Peter Almgren, Tiinamaija Tuomi, Daniel Gaudet, Thomas J. Hudson, Kristin G. Ardlie, Mark J. Daly, Joel N. Hirschhorn, Leif Groop, and David Altshuler
Diabetes 2005 54: 886 -892. [Abstract] [Full Text] [PDF] Appendix

The Common Polymorphisms (Single Nucleotide Polymorphism [SNP] +45 and SNP +276) of the Adiponectin Gene Predict the Conversion From Impaired Glucose Tolerance to Type 2 Diabetes: The STOP-NIDDM Trial: Jelena Zacharova, Jean-Louis Chiasson, Markku Laakso the STOP-NIDDM Study Group
Diabetes 2005 54: 893 -899. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

Retrovirus-Like Long-Terminal Repeat DQ-LTR13 and Genetic Susceptibility to Type 1 Diabetes and Autoimmune Addison’s Disease: Giovanni Gambelunghe, Ingrid Kockum, Vittorio Bini, Giovanni De Giorgi, Federica Celi, Corrado Betterle, Roberta Giordano, Rossella Libè, Alberto Falorni on behalf of the Umbria Type 1 Diabetes Registry and the Italian Addison Network
Diabetes 2005 54: 900 -905. [Abstract] [Full Text] [PDF]

Genetic Association Between a Lymphoid Tyrosine Phosphatase (PTPN22) and Type 1 Diabetes: Weipeng Zheng and Jin-Xiong She
Diabetes 2005 54: 906 -908. [Abstract] [Full Text] [PDF]

Genome-wide Linkage Scans for Fasting Glucose, Insulin, and Insulin Resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: Evidence of Linkages to Chromosome 7q36 and 19q13 From Meta-Analysis: Ping An, Barry I. Freedman, Craig L. Hanis, Yii-Der I. Chen, Alan B. Weder, Nicholas J. Schork, Eric Boerwinkle, Michael A. Province, Chao Agnes Hsiung, Xiaodong Wu, Thomas Quertermous, and D.C. Rao
Diabetes 2005 54: 909 -914. [Abstract] [Full Text] [PDF]