Diabetes -- Table of Contents (October 2007, 56 [10])

Commentary:

Testing the Gene or Testing a Variant?: The Case of TCF7L2: Mark O. Goodarzi and Jerome I. Rotter
Diabetes 2007 56: 2417 -2419. [Extract] [Full Text] [PDF]

Perspectives in Diabetes:

Estimation of ß-Cell Mass by Metabolic Tests: Necessary, but How Sufficient?: R. Paul Robertson
Diabetes 2007 56: 2420 -2424. First published on July 2, 2007 as 10.2337/db07-0742 [Abstract] [Full Text] [PDF]

Metabolism:

L-Carnosine, a Substrate of Carnosinase-1, Influences Glucose Metabolism: Sibylle Sauerhöfer, Gang Yuan, Gerald Stefan Braun, Martina Deinzer, Michael Neumaier, Norbert Gretz, Jürgen Floege, Wilhelm Kriz, Fokko van der Woude, and Marcus Johannes Moeller
Diabetes 2007 56: 2425 -2432. First published on June 29, 2007 as 10.2337/db07-0177 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women: Studies in the Postprandial State: Leanne Hodson, Alex S.T. Bickerton, Siobhán E. McQuaid, Rachel Roberts, Fredrik Karpe, Keith N. Frayn, and Barbara A. Fielding
Diabetes 2007 56: 2433 -2441. First published on June 29, 2007 as 10.2337/db07-0654 [Abstract] [Full Text] [PDF] Online-Only Appendix

Glucagon, in Concert With Insulin, Supports the Postabsorptive Plasma Glucose Concentration in Humans: Suzanne M. Breckenridge, Benjamin A. Cooperberg, Ana Maria Arbelaez, Bruce W. Patterson, and Philip E. Cryer
Diabetes 2007 56: 2442 -2448. First published on July 2, 2007 as 10.2337/db07-0751 [Abstract] [Full Text] [PDF]

PTEN Expression Contributes to the Regulation of Muscle Protein Degradation in Diabetes: Zhaoyong Hu, In Hee Lee, Xiaonan Wang, Hongmiao Sheng, Liping Zhang, Jie Du, and William E. Mitch
Diabetes 2007 56: 2449 -2456. First published on July 10, 2007 as 10.2337/db06-1731 [Abstract] [Full Text] [PDF]

Mitochondrial Energetics in the Heart in Obesity-Related Diabetes: Direct Evidence for Increased Uncoupled Respiration and Activation of Uncoupling Proteins: Sihem Boudina, Sandra Sena, Heather Theobald, Xiaoming Sheng, Jordan J. Wright, Xia Xuan Hu, Salwa Aziz, Josie I. Johnson, Heiko Bugger, Vlad G. Zaha, and E. Dale Abel
Diabetes 2007 56: 2457 -2466. First published on July 10, 2007 as 10.2337/db07-0481 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Transcriptional Coactivator Peroxisome Proliferator–Activated Receptor (PPAR) ${gamma}$ Coactivator-1 ${alpha}$ and the Nuclear Receptor PPAR ${alpha}$ Control the Expression of Glycerol Kinase and Metabolism Genes Independently of PPAR ${gamma}$ Activation in Human White Adipocytes: Anne Mazzucotelli, Nathalie Viguerie, Claire Tiraby, Jean-Sébastien Annicotte, Aline Mairal, Eva Klimcakova, Emmanuelle Lepin, Paul Delmar, Sébastien Dejean, Geneviève Tavernier, Corinne Lefort, Juan Hidalgo, Thierry Pineau, Lluis Fajas, Karine Clément, and Dominique Langin
Diabetes 2007 56: 2467 -2475. First published on July 23, 2007 as 10.2337/db06-1465 [Abstract] [Full Text] [PDF] Online-Only Appendix

Phosphorylation Barriers to Skeletal and Cardiac Muscle Glucose Uptakes in High-Fat–Fed Mice: Studies in Mice With a 50% Reduction of Hexokinase II: Patrick T. Fueger, Robert S. Lee-Young, Jane Shearer, Deanna P. Bracy, Sami Heikkinen, Markku Laakso, Jeffrey N. Rottman, and David H. Wasserman
Diabetes 2007 56: 2476 -2484. First published on July 16, 2007 as 10.2337/db07-0532 [Abstract] [Full Text] [PDF]

Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy: Tao Jiang, Xiaoxin X. Wang, Pnina Scherzer, Paul Wilson, James Tallman, Hideaki Takahashi, Jinping Li, Mieko Iwahashi, Eileen Sutherland, Lois Arend, and Moshe Levi
Diabetes 2007 56: 2485 -2493. First published on July 27, 2007 as 10.2337/db06-1642 [Abstract] [Full Text] [PDF]

Signal Transduction:

Orexins Control Intestinal Glucose Transport by Distinct Neuronal, Endocrine, and Direct Epithelial Pathways: Robert Ducroc, Thierry Voisin, Aadil El Firar, and Marc Laburthe
Diabetes 2007 56: 2494 -2500. First published on July 12, 2007 as 10.2337/db07-0614 [Abstract] [Full Text] [PDF]

FGFR4 Prevents Hyperlipidemia and Insulin Resistance but Underlies High-Fat Diet–Induced Fatty Liver: Xinqiang Huang, Chaofeng Yang, Yongde Luo, Chengliu Jin, Fen Wang, and Wallace L. McKeehan
Diabetes 2007 56: 2501 -2510. First published on July 30, 2007 as 10.2337/db07-0648 [Abstract] [Full Text] [PDF] Online-Only Appendix

Obesity Studies:

Deficiency of Cbl-b Gene Enhances Infiltration and Activation of Macrophages in Adipose Tissue and Causes Peripheral Insulin Resistance in Mice: Katsuya Hirasaka, Shohei Kohno, Jumpei Goto, Harumi Furochi, Kazuaki Mawatari, Nagakatsu Harada, Toshio Hosaka, Yutaka Nakaya, Kazumi Ishidoh, Toshiyuki Obata, Yousuke Ebina, Hua Gu, Shin'ichi Takeda, Kyoichi Kishi, and Takeshi Nikawa
Diabetes 2007 56: 2511 -2522. First published on June 29, 2007 as 10.2337/db06-1768 [Abstract] [Full Text] [PDF] Online-Only Appendix

Cideb Regulates Diet-Induced Obesity, Liver Steatosis, and Insulin Sensitivity by Controlling Lipogenesis and Fatty Acid Oxidation: John Zhong Li, Jing Ye, Bofu Xue, Jingzhong Qi, Jing Zhang, Zhihong Zhou, Qing Li, Zilong Wen, and Peng Li
Diabetes 2007 56: 2523 -2532. First published on July 23, 2007 as 10.2337/db07-0040 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Adipokine Lipocalin 2 Is Regulated by Obesity and Promotes Insulin Resistance: Qing-Wu Yan, Qin Yang, Nimesh Mody, Timothy E. Graham, Chung-Hsin Hsu, Zhao Xu, Nicholas E. Houstis, Barbara B. Kahn, and Evan D. Rosen
Diabetes 2007 56: 2533 -2540. First published on July 16, 2007 as 10.2337/db07-0007 [Abstract] [Full Text] [PDF]

Mice Heterozygous for Tumor Necrosis Factor- ${alpha}$ Converting Enzyme Are Protected From Obesity-Induced Insulin Resistance and Diabetes: Matteo Serino, Rossella Menghini, Loredana Fiorentino, Roberta Amoruso, Alessandro Mauriello, Davide Lauro, Paolo Sbraccia, Marta L. Hribal, Renato Lauro, and Massimo Federici
Diabetes 2007 56: 2541 -2546. First published on July 23, 2007 as 10.2337/db07-0360 [Abstract] [Full Text] [PDF] Online-Only Appendix

Glucose Ingestion Fails to Inhibit Hypothalamic Neuronal Activity in Patients With Type 2 Diabetes: Solrun Vidarsdottir, Paul A.M. Smeets, Diane L. Eichelsheim, Matthias J.P. van Osch, Max A. Viergever, Johannes A. Romijn, Jeroen van der Grond, and Hanno Pijl
Diabetes 2007 56: 2547 -2550. First published on August 1, 2007 as 10.2337/db07-0193 [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

In Vivo Cytotoxicity of Insulin-Specific CD8⁺ T-Cells in HLA-A*0201 Transgenic NOD Mice: Irene Jarchum, Jason C. Baker, Tatsuya Yamada, Toshiyuki Takaki, Michele P. Marron, David V. Serreze, and Teresa P. DiLorenzo
Diabetes 2007 56: 2551 -2560. First published on July 9, 2007 as 10.2337/db07-0332 [Abstract] [Full Text] [PDF]

Islet Studies:

Essential Role for Signal Transducer and Activator of Transcription-1 in Pancreatic ß-Cell Death and Autoimmune Type 1 Diabetes of Nonobese Diabetic Mice: Sunshin Kim, Hun Sik Kim, Kun Wook Chung, Seung Hoon Oh, Jong Won Yun, Sin-Hyeog Im, Moon-Kyu Lee, Kwang-Won Kim, and Myung-Shik Lee
Diabetes 2007 56: 2561 -2568. First published on July 9, 2007 as 10.2337/db06-1372 [Abstract] [Full Text] [PDF] Online-Only Appendix

ß-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels: Jakob D. Wikstrom, Shana M. Katzman, Hibo Mohamed, Gilad Twig, Solomon A. Graf, Emma Heart, Anthony J.A. Molina, Barbara E. Corkey, Lina Moitoso de Vargas, Nika N. Danial, Sheila Collins, and Orian S. Shirihai
Diabetes 2007 56: 2569 -2578. First published on August 8, 2007 as 10.2337/db06-0757 [Abstract] [Full Text] [PDF] Online-Only Appendix

Interaction Between Munc13-1 and RIM Is Critical for Glucagon-Like Peptide-1–Mediated Rescue of Exocytotic Defects in Munc13-1–Deficient Pancreatic ß-Cells: Edwin P. Kwan, Li Xie, Laura Sheu, Toshihisa Ohtsuka, and Herbert Y. Gaisano
Diabetes 2007 56: 2579 -2588. First published on July 16, 2007 as 10.2337/db06-1207 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pathophysiology:

Meal Fatty Acid Uptake in Visceral Fat in Women: Susanne B. Votruba, Rebecca S. Mattison, Daniel A. Dumesic, Christina Koutsari, and Michael D. Jensen
Diabetes 2007 56: 2589 -2597. First published on July 30, 2007 as 10.2337/db07-0439 [Abstract] [Full Text] [PDF]

Complications:

High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity: Effects of "Healthy" Diet and Aldose Reductase Inhibition: Irina G. Obrosova, Olga Ilnytska, Valeriy V. Lyzogubov, Ivan A. Pavlov, Nazar Mashtalir, Jerry L. Nadler, and Viktor R. Drel
Diabetes 2007 56: 2598 -2608. First published on July 12, 2007 as 10.2337/db06-1176 [Abstract] [Full Text] [PDF]

Pharmacology and Therapeutics:

The Peroxisome Proliferator–Activated Receptor- ${gamma}$ Agonist Pioglitazone Increases Number and Function of Endothelial Progenitor Cells in Patients With Coronary Artery Disease and Normal Glucose Tolerance: Christian Werner, Christel Hermann Kamani, Christoph Gensch, Michael Böhm, and Ulrich Laufs
Diabetes 2007 56: 2609 -2615. First published on July 10, 2007 as 10.2337/db07-0069 [Abstract] [Full Text] [PDF]

Genetics:

Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes: Rebecca Bailey, Jason D. Cooper, Lauren Zeitels, Deborah J. Smyth, Jennie H.M. Yang, Neil M. Walker, Elina Hyppönen, David B. Dunger, Elizabeth Ramos-Lopez, Klaus Badenhoop, Sergey Nejentsev, and John A. Todd
Diabetes 2007 56: 2616 -2621. First published on July 2, 2007 as 10.2337/db07-0652 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Role of Melanocortin 3 Receptor Gene in Childhood Obesity: Yung Seng Lee, Larry Kok Seng Poh, Betty Lay Kee Kek, and Kah Yin Loke
Diabetes 2007 56: 2622 -2630. First published on July 16, 2007 as 10.2337/db07-0225 [Abstract] [Full Text] [PDF]

Association Study of the Genetic Polymorphisms of the Transcription Factor 7-Like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Yi-Cheng Chang, Tien-Jyun Chang, Yi-Der Jiang, Shan-Shan Kuo, Kuan-Ching Lee, Ken C. Chiu, and Lee-Ming Chuang
Diabetes 2007 56: 2631 -2637. First published on June 19, 2007 as 10.2337/db07-0421 [Abstract] [Full Text] [PDF]

Variants of the Transcription Factor 7-Like 2 (TCF7L2) Gene Are Associated With Type 2 Diabetes in an African-American Population Enriched for Nephropathy: Michèle M. Sale, Shelly G. Smith, Josyf C. Mychaleckyj, Keith L. Keene, Carl D. Langefeld, Tennille S. Leak, Pamela J. Hicks, Donald W. Bowden, Stephen S. Rich, and Barry I. Freedman
Diabetes 2007 56: 2638 -2642. First published on June 29, 2007 as 10.2337/db07-0012 [Abstract] [Full Text] [PDF] Online-Only Appendix

A Genome-Wide Linkage Scan of Insulin Level–Derived Traits: The Amish Family Diabetes Study: Wen-Chi Hsueh, Kristi D. Silver, Toni I. Pollin, Callum J. Bell, Jeffrey R. O’Connell, Braxton D. Mitchell, and Alan R. Shuldiner
Diabetes 2007 56: 2643 -2648. First published on July 23, 2007 as 10.2337/db06-1023 [Abstract] [Full Text] [PDF] Online-Only Appendix

Errata:

Errata: Diabetes 2007 56: 2649 . [Extract] [Full Text] [PDF]

Errata: Diabetes 2007 56: 2649 . [Extract] [Full Text] [PDF]

ERRATA: Diabetes 2007 56: 2650 . [Extract] [Full Text] [PDF]

ERRATA: Diabetes 2007 56: 2650 . [Extract] [Full Text] [PDF]

Online Letters to the Editor:

Response to Comment on: Harmancey et al. (2007) Adrenomedullin Inhibits Adipogenesis Under Transcriptional Control of Insulin: Diabetes 56:553–563: Romain Harmancey and Fatima Smih
Diabetes 2007 56: e18 . [Extract] [Full Text] [PDF]

Comment on: Buchanan (2007) (How) Can We Prevent Type 2 Diabetes? Diabetes 56:1502–1507: Lawrence S. Phillips
Diabetes 2007 56: e19 . [Extract] [Full Text] [PDF]