Diabetes -- Table of Contents (February 2007, 56 [2])

Obesity Studies:

IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance: Stephen B. Wheatcroft, Mark T. Kearney, Ajay M. Shah, Vivienne A. Ezzat, John R. Miell, Michael Modo, Stephen C.R. Williams, Will P. Cawthorn, Gema Medina-Gomez, Antonio Vidal-Puig, Jaswinder K. Sethi, and Paul A. Crossey
Diabetes 2007 56: 285 -294. [Abstract] [Full Text] [PDF]

Wnt10b Inhibits Obesity in ob/ob and Agouti Mice: Wendy S. Wright, Kenneth A. Longo, Vernon W. Dolinsky, Isabelle Gerin, Sona Kang, Christina N. Bennett, Shian-Huey Chiang, Tyler C. Prestwich, Catherine Gress, Charles F. Burant, Vedrana S. Susulic, and Ormond A. MacDougald
Diabetes 2007 56: 295 -303. [Abstract] [Full Text] [PDF]

Islet Studies:

Identification of the Amyloid-Degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis: Sakeneh Zraika, Rebecca L. Hull, Jayalakshmi Udayasankar, Anne Clark, Kristina M. Utzschneider, Jenny Tong, Fernando Gerchman, and Steven E. Kahn
Diabetes 2007 56: 304 -310. [Abstract] [Full Text] [PDF]

Melanin Concentrating Hormone Is a Novel Regulator of Islet Function and Growth: Pavlos Pissios, Umut Ozcan, Efi Kokkotou, Terumasa Okada, Chong Wee Liew, Siming Liu, Jennifer N. Peters, Gabriella Dahlgren, Jason Karamchandani, Yogish C. Kudva, Amarnath J. Kurpad, Robert T. Kennedy, Eleftheria Maratos-Flier, and Rohit N. Kulkarni
Diabetes 2007 56: 311 -319. [Abstract] [Full Text] [PDF]

Glucose-Dependent Regulation of ${gamma}$ -Aminobutyric Acid (GABA_A) Receptor Expression in Mouse Pancreatic Islet ${alpha}$ -Cells: Sarah J. Bailey, Magalie A. Ravier, and Guy A. Rutter
Diabetes 2007 56: 320 -327. [Abstract] [Full Text] [PDF]

An ATP-Binding Mutation (G334D) in KCNJ11 Is Associated With a Sulfonylurea-Insensitive Form of Developmental Delay, Epilepsy, and Neonatal Diabetes: Ricard Masia, Joseph C. Koster, Stefano Tumini, Francesco Chiarelli, Carlo Colombo, Colin G. Nichols, and Fabrizio Barbetti
Diabetes 2007 56: 328 -336. [Abstract] [Full Text] [PDF]

Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner: Keun-Gyu Park, Kyeong-Min Lee, Hye-Young Seo, Ji-Ho Suh, Hye-Soon Kim, Li Wang, Kyu-Chang Won, Hyoung-Woo Lee, Joong-Yeol Park, Ki-Up Lee, Jung-Guk Kim, Bo-Wan Kim, Hueng-Sik Choi, and In-Kyu Lee
Diabetes 2007 56: 431 -437. [Abstract] [Full Text] [PDF] Online-Only Appendix

Sulfonylurea Compounds Uncouple the Glucose Dependence of the Insulinotropic Effect of Glucagon-Like Peptide 1: Jocelyn de Heer and Jens J. Holst
Diabetes 2007 56: 438 -443. [Abstract] [Full Text] [PDF]

Complications:

Salicylate-Based Anti-Inflammatory Drugs Inhibit the Early Lesion of Diabetic Retinopathy: Ling Zheng, Scott J. Howell, Denise A. Hatala, Kun Huang, and Timothy S. Kern
Diabetes 2007 56: 337 -345. [Abstract] [Full Text] [PDF]

Deletion of Protein Kinase C-ß Isoform In Vivo Reduces Renal Hypertrophy but Not Albuminuria in the Streptozotocin-Induced Diabetic Mouse Model: Matthias Meier, Joon-Keun Park, Daniel Overheu, Torsten Kirsch, Carsten Lindschau, Faikah Gueler, Michael Leitges, Jan Menne, and Hermann Haller
Diabetes 2007 56: 346 -354. [Abstract] [Full Text] [PDF]

Treatment of Streptozotocin-Induced Diabetic Rats With AVE7688, a Vasopeptidase Inhibitor: Effect on Vascular and Neural Disease: Eric P. Davidson, Travis L. Kleinschmidt, Christine L. Oltman, Donald D. Lund, and Mark A. Yorek
Diabetes 2007 56: 355 -362. [Abstract] [Full Text] [PDF]

Macrophage Scavenger Receptor-A–Deficient Mice Are Resistant Against Diabetic Nephropathy Through Amelioration of Microinflammation: Hitomi Kataoka Usui, Kenichi Shikata, Motofumi Sasaki, Shinichi Okada, Mitsuhiro Matsuda, Yasushi Shikata, Daisuke Ogawa, Yuichi Kido, Ryo Nagase, Kosuke Yozai, Sakiko Ohga, Atsuhito Tone, Jun Wada, Motohiro Takeya, Seikoh Horiuchi, Tatsuhiko Kodama, and Hirofumi Makino
Diabetes 2007 56: 363 -372. [Abstract] [Full Text] [PDF]

Topical Administration of Nepafenac Inhibits Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology: Timothy S. Kern, Casey M. Miller, Yunpeng Du, Ling Zheng, Susanne Mohr, Sherry L. Ball, M. Kim, Jeffrey A. Jamison, and David P. Bingaman
Diabetes 2007 56: 373 -379. [Abstract] [Full Text] [PDF]

Evidence for a Role of Transforming Growth Factor (TGF)-ß1 in the Induction of Postglomerular Albuminuria in Diabetic Nephropathy: Amelioration by Soluble TGF-ß Type II Receptor: Leileata M. Russo, Elisabetta del Re, Dennis Brown, and Herbert Y. Lin
Diabetes 2007 56: 380 -388. [Abstract] [Full Text] [PDF]

Alterations of Adenine Nucleotide Metabolism and Function of Blood Platelets in Patients With Diabetes: Anna Michno, Hanna Bielarczyk, Tadeusz Pawelczyk, Agnieszka Jankowska-Kulawy, Joanna Klimaszewska, and Andrzej Szutowicz
Diabetes 2007 56: 462 -467. [Abstract] [Full Text] [PDF]

Impact of Type 2 Diabetes on Nitric Oxide and Adrenergic Modulation of Myocardial Perfusion: Mette M. Madsen, Hanne M. Søndergaard, Morten Bøttcher, Niels H. Buus, Ole Schmitz, Hans E. Bøtker, and Torsten T. Nielsen
Diabetes 2007 56: 468 -475. [Abstract] [Full Text] [PDF]

High Glucose, High Insulin, and Their Combination Rapidly Induce Laminin-ß1 Synthesis by Regulation of mRNA Translation in Renal Epithelial Cells: Meenalakshmi M. Mariappan, Denis Feliers, Srinivas Mummidi, Goutam Ghosh Choudhury, and Balakuntalam S. Kasinath
Diabetes 2007 56: 476 -485. [Abstract] [Full Text] [PDF] Online-Only Appendix

Brief Reports:

Haplotypes of Transcription Factor 7–Like 2 (TCF7L2) Gene and Its Upstream Region Are Associated With Type 2 Diabetes and Age of Onset in Mexican Americans: Donna M. Lehman, Kelly J. Hunt, Robin J. Leach, Jeanette Hamlington, Rector Arya, Hanna E. Abboud, Ravindranath Duggirala, John Blangero, Harald H.H. Göring, and Michael P. Stern
Diabetes 2007 56: 389 -393. [Abstract] [Full Text] [PDF]

P2 Promoter Variants of the Hepatocyte Nuclear Factor 4 ${alpha}$ Gene Are Associated With Type 2 Diabetes in Mexican Americans: Donna M. Lehman, Dawn K. Richardson, Chris P. Jenkinson, Kelly J. Hunt, Thomas D. Dyer, Robin J. Leach, Rector Arya, Hanna E. Abboud, John Blangero, Ravindranath Duggirala, and Michael P. Stern
Diabetes 2007 56: 513 -517. [Abstract] [Full Text] [PDF]

Women With Mitochondrial Haplogroup N9a Are Protected Against Metabolic Syndrome: Masashi Tanaka, Noriyuki Fuku, Yutaka Nishigaki, Hitoshi Matsuo, Tomonori Segawa, Sachiro Watanabe, Kimihiko Kato, Kiyoshi Yoko, Masafumi Ito, Yoshinori Nozawa, and Yoshiji Yamada
Diabetes 2007 56: 518 -521. [Abstract] [Full Text] [PDF] Online-Only Appendix

PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits: Claude Chelala, Sabine Duchatelet, Marie-Line Joffret, Regine Bergholdt, Danièle Dubois-Laforgue, Pegah Ghandil, Flemming Pociot, Sophie Caillat-Zucman, José Timsit, and Cécile Julier
Diabetes 2007 56: 522 -526. [Abstract] [Full Text] [PDF] Online-Only Appendix

Myocardial Uptake of Circulating Triglycerides in Nondiabetic Patients With Heart Disease: Robert H. Nelson, Abhiram Prasad, Amir Lerman, and John M. Miles
Diabetes 2007 56: 527 -530. [Abstract] [Full Text] [PDF]

Type 2 Diabetes–Associated Missense Polymorphisms KCNJ11 E23K and ABCC8 A1369S Influence Progression to Diabetes and Response to Interventions in the Diabetes Prevention Program: Jose C. Florez, Kathleen A. Jablonski, Steven E. Kahn, Paul W. Franks, Dana Dabelea, Richard F. Hamman, William C. Knowler, David M. Nathan, David Altshuler for the Diabetes Prevention Program Research Group
Diabetes 2007 56: 531 -536. [Abstract] [Full Text] [PDF]

Linkage and Association Analyses of Type 2 Diabetes/Impaired Glucose Metabolism and Adiponectin Serum Levels in Japanese Americans From Hawaii: Ilija P. Kovac, Richard J. Havlik, Daniel Foley, Rita Peila, Dena Hernandez, Fabienne Wavrant-De Vrièze, Andrew Singleton, Josephine Egan, Dennis Taub, Beatriz Rodriguez, Kamal Masaki, J. David Curb, Wilfred Y. Fujimoto, and Alexander F. Wilson
Diabetes 2007 56: 537 -540. [Abstract] [Full Text] [PDF]

Signal Transduction:

Ceramide- and Oxidant-Induced Insulin Resistance Involve Loss of Insulin-Dependent Rac-Activation and Actin Remodeling in Muscle Cells: Lellean JeBailey, Oshrit Wanono, Wenyan Niu, Jessica Roessler, Assaf Rudich, and Amira Klip
Diabetes 2007 56: 394 -403. [Abstract] [Full Text] [PDF] Online-Only Appendix

Protein–Tyrosine Phosphatase 1B–Deficient Myocytes Show Increased Insulin Sensitivity and Protection Against Tumor Necrosis Factor- ${alpha}$ –Induced Insulin Resistance: Iria Nieto-Vazquez, Sonia Fernández-Veledo, Cristina de Alvaro, Cristina M. Rondinone, Angela M. Valverde, and Margarita Lorenzo
Diabetes 2007 56: 404 -413. [Abstract] [Full Text] [PDF]

The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic: Farah S.L. Thong, Philip J. Bilan, and Amira Klip
Diabetes 2007 56: 414 -423. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Cellular Expression Requirements for Inhibition of Type 1 Diabetes by a Dominantly Protective Major Histocompatibility Complex Haplotype: Yi-Guang Chen, Pablo A. Silveira, Melissa A. Osborne, Harold D. Chapman, and David V. Serreze
Diabetes 2007 56: 424 -430. [Abstract] [Full Text] [PDF]

Pathophysiology:

Pancreatic Lipomatosis Is a Structural Marker in Nondiabetic Children With Mutations in Carboxyl-Ester Lipase: Helge Ræder, Ingfrid S. Haldorsen, Lars Ersland, Renate Grüner, Torfinn Taxt, Oddmund Søvik, Anders Molven, and Pål R. Njølstad
Diabetes 2007 56: 444 -449. [Abstract] [Full Text] [PDF] Online-Only Appendix

Tumor Necrosis Factor- ${alpha}$ Induces Intestinal Insulin Resistance and Stimulates the Overproduction of Intestinal Apolipoprotein B48-Containing Lipoproteins: Bolin Qin, Wei Qiu, Rita Kohen Avramoglu, and Khosrow Adeli
Diabetes 2007 56: 450 -461. [Abstract] [Full Text] [PDF]

Pharmacology and Therapeutics:

Oral Insulin-Mimetic Compounds That Act Independently of Insulin: Silvia García-Vicente, Francesc Yraola, Luc Marti, Elena González-Muñoz, María José García-Barrado, Carles Cantó, Anna Abella, Sandy Bour, Rafael Artuch, Cristina Sierra, Nuria Brandi, Christian Carpéné, Julio Moratinos, Marta Camps, Manuel Palacín, Xavier Testar, Anna Gumà, Fernando Albericio, Miriam Royo, Alec Mian, and Antonio Zorzano
Diabetes 2007 56: 486 -493. [Abstract] [Full Text] [PDF] Online-Only Appendix

Genetics:

A Possible Role for the PPARG Pro12Ala Polymorphism in Preterm Birth: Aline Meirhaeghe, Colin A.G. Boreham, Liam J. Murray, Florence Richard, George Davey Smith, Ian S. Young, and Philippe Amouyel
Diabetes 2007 56: 494 -498. [Abstract] [Full Text] [PDF]

Tag Polymorphisms at the A20 (TNFAIP3) Locus Are Associated With Lower Gene Expression and Increased Risk of Coronary Artery Disease in Type 2 Diabetes: Watip Boonyasrisawat, Delphine Eberle, Simonetta Bacci, Yuan-Yuan Zhang, David Nolan, Ernest V. Gervino, Michael T. Johnstone, Vincenzo Trischitta, Steven E. Shoelson, and Alessandro Doria
Diabetes 2007 56: 499 -505. [Abstract] [Full Text] [PDF] Online-Only Appendix

Genetic Reconstitution of Autoimmune Type 1 Diabetes With Two Major Susceptibility Genes in the Rat: Norihide Yokoi, Chihiro Hayashi, Yuuka Fujiwara, He-Yao Wang, and Susumu Seino
Diabetes 2007 56: 506 -512. [Abstract] [Full Text] [PDF]

Perspectives in Diabetes:

Diabetes and Suppressors of Cytokine Signaling Proteins: Sif G. Rønn, Nils Billestrup, and Thomas Mandrup-Poulsen
Diabetes 2007 56: 541 -548. [Extract] [Full Text] [PDF]

Errata:

Errata: Diabetes 2007 56: 549 . [Extract] [Full Text] [PDF]