Diabetes -- Table of Contents (May 2007, 56 [5])

Perspectives in Diabetes:

The Heterogeneity of Diabetes: Unraveling a Dispute: Is Systemic Inflammation Related to Islet Autoimmunity?: Massimo Pietropaolo, Emma Barinas-Mitchell, and Lewis H. Kuller
Diabetes 2007 56: 1189 -1197. First published on February 23, 2007 as 10.2337/db06-0880 [Abstract] [Full Text] [PDF] Figures

Genetic Influences of Adiponectin on Insulin Resistance, Type 2 Diabetes, and Cardiovascular Disease: Claudia Menzaghi, Vincenzo Trischitta, and Alessandro Doria
Diabetes 2007 56: 1198 -1209. First published on February 15, 2007 as 10.2337/db06-0506 [Abstract] [Full Text] [PDF]

Signal Transduction:

Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes: Hongmei Zhao, Malgorzata Przybylska, I-Huan Wu, Jinhua Zhang, Craig Siegel, Svetlana Komarnitsky, Nelson S. Yew, and Seng H. Cheng
Diabetes 2007 56: 1210 -1218. [Abstract] [Full Text] [PDF]

Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells: Kenneth K.Y. Cheng, Karen S.L. Lam, Yu Wang, Yu Huang, David Carling, Donghai Wu, Chiwai Wong, and Aimin Xu
Diabetes 2007 56: 1387 -1394. First published on February 7, 2007 as 10.2337/db06-1580 [Abstract] [Full Text] [PDF] Online-Only Appendix

Obesity Studies:

Characterization of Glucosensing Neuron Subpopulations in the Arcuate Nucleus: Integration in Neuropeptide Y and Pro-Opio Melanocortin Networks?: Xavier Fioramonti, Sylvain Contié, Zhentao Song, Vanessa H. Routh, Anne Lorsignol, and Luc Pénicaud
Diabetes 2007 56: 1219 -1227. First published on January 29, 2007 as 10.2337/db06-0567 [Abstract] [Full Text] [PDF]

Loss of Stearoyl-CoA Desaturase-1 Improves Insulin Sensitivity in Lean Mice but Worsens Diabetes in Leptin-Deficient Obese Mice: Jessica B. Flowers, Mary E. Rabaglia, Kathryn L. Schueler, Matthew T. Flowers, Hong Lan, Mark P. Keller, James M. Ntambi, and Alan D. Attie
Diabetes 2007 56: 1228 -1239. First published on March 16, 2007 as 10.2337/db06-1142 [Abstract] [Full Text] [PDF] Online-Only Appendix

Immunology and Transplantation:

Systemic Expression of Heme Oxygenase-1 Ameliorates Type 1 Diabetes in NOD Mice: Chien-Ming Hu, Heng-Huei Lin, Ming-Tsai Chiang, Pi-Fei Chang, and Lee-Young Chau
Diabetes 2007 56: 1240 -1247. First published on February 15, 2007 as 10.2337/db06-0495 [Abstract] [Full Text] [PDF]

The Type and Frequency of Immunoregulatory CD4⁺ T-Cells Govern the Efficacy of Antigen-Specific Immunotherapy in Nonobese Diabetic Mice: Shannon M. Pop, Carmen P. Wong, Qiuming He, Yaming Wang, Mark A. Wallet, Kevin S. Goudy, and Roland Tisch
Diabetes 2007 56: 1395 -1402. First published on February 22, 2007 as 10.2337/db06-0543 [Abstract] [Full Text] [PDF]

Islet Studies:

Control of ß-Cell Differentiation by the Pancreatic Mesenchyme: Myriam Attali, Volodymyr Stetsyuk, Annie Basmaciogullari, Virginie Aiello, Maria A. Zanta-Boussif, Bertrand Duvillie, and Raphael Scharfmann
Diabetes 2007 56: 1248 -1258. First published on February 23, 2007 as 10.2337/db06-1307 [Abstract] [Full Text] [PDF]

Cell-Permeable Pentapeptide V5 Inhibits Apoptosis and Enhances Insulin Secretion, Allowing Experimental Single-Donor Islet Transplantation in Mice: Jorge D. Rivas-Carrillo, Alejandro Soto-Gutierrez, Nalu Navarro-Alvarez, Hirofumi Noguchi, Teru Okitsu, Yong Chen, Takeshi Yuasa, Kimiaki Tanaka, Michiki Narushima, Atsushi Miki, Haruo Misawa, Yasuhiko Tabata, Hee-Sook Jun, Shinichi Matsumoto, Ira J. Fox, Noriaki Tanaka, and Naoya Kobayashi
Diabetes 2007 56: 1259 -1267. First published on February 7, 2007 as 10.2337/db06-1679 [Abstract] [Full Text] [PDF] Online-Only Appendix

Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe ß-Cell Loss in Munich Ins2^C95S Mutant Mice: Nadja Herbach, Birgit Rathkolb, Elisabeth Kemter, Lisa Pichl, Matthias Klaften, Martin Hrabé de Angelis, Philippe A. Halban, Eckhard Wolf, Bernhard Aigner, and Ruediger Wanke
Diabetes 2007 56: 1268 -1276. First published on February 15, 2007 as 10.2337/db06-0658 [Abstract] [Full Text] [PDF]

Human Insulin Vesicle Dynamics During Pulsatile Secretion: Darren J. Michael, Wenyong Xiong, Xuehui Geng, Peter Drain, and Robert H. Chow
Diabetes 2007 56: 1277 -1288. First published on February 22, 2007 as 10.2337/db06-0367 [Abstract] [Full Text] [PDF] Figures Table 1 Online-Only Appendix

Caspase Inhibitor Therapy Enhances Marginal Mass Islet Graft Survival and Preserves Long-Term Function in Islet Transplantation: Juliet A. Emamaullee, Laura Stanton, Colleen Schur, and A.M. James Shapiro
Diabetes 2007 56: 1289 -1298. First published on February 15, 2007 as 10.2337/db06-1653 [Abstract] [Full Text] [PDF]

Lineage Tracing Evidence for In Vitro Dedifferentiation but Rare Proliferation of Mouse Pancreatic ß-Cells: Noa Weinberg, Limor Ouziel-Yahalom, Sarah Knoller, Shimon Efrat, and Yuval Dor
Diabetes 2007 56: 1299 -1304. First published on February 15, 2007 as 10.2337/db06-1654 [Abstract] [Full Text] [PDF] Online-Only Appendix

Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 ß-Cells: Simone Baltrusch and Sigurd Lenzen
Diabetes 2007 56: 1305 -1315. First published on February 7, 2007 as 10.2337/db06-0894 [Abstract] [Full Text] [PDF]

${alpha}$ 1-Antitrypsin Protects ß-Cells From Apoptosis: Bin Zhang, Yuanqing Lu, Martha Campbell-Thompson, Terry Spencer, Clive Wasserfall, Mark Atkinson, and Sihong Song
Diabetes 2007 56: 1316 -1323. First published on March 14, 2007 as 10.2337/db06-1273 [Abstract] [Full Text] [PDF]

Toxic Human Islet Amyloid Polypeptide (h-IAPP) Oligomers Are Intracellular, and Vaccination to Induce Anti-Toxic Oligomer Antibodies Does Not Prevent h-IAPP–Induced ß-Cell Apoptosis in h-IAPP Transgenic Mice: Chia-Yu Lin, Tatyana Gurlo, Rakez Kayed, Alexandra E. Butler, Leena Haataja, Charles G. Glabe, and Peter C. Butler
Diabetes 2007 56: 1324 -1332. First published on March 12, 2007 as 10.2337/db06-1579 [Abstract] [Full Text] [PDF]

Complications:

Glial Cell–Derived Cytokines Attenuate the Breakdown of Vascular Integrity in Diabetic Retinopathy: Nami Nishikiori, Makoto Osanai, Hideki Chiba, Takashi Kojima, Yoshinori Mitamura, Hiroshi Ohguro, and Norimasa Sawada
Diabetes 2007 56: 1333 -1340. First published on May 1, 2007 as 10.2337/db06-1431 [Abstract] [Full Text] [PDF]

Effects of Insulin Replacements, Inhibitors of Angiotensin, and PKCß's Actions to Normalize Cardiac Gene Expression and Fuel Metabolism in Diabetic Rats: Emi Arikawa, Ronald C.W. Ma, Keiji Isshiki, Ivan Luptak, Zhiheng He, Yutaka Yasuda, Yasuhiro Maeno, Mary Elizabeth Patti, Gordon C. Weir, Robert A. Harris, Victor A. Zammit, Rong Tian, and George L. King
Diabetes 2007 56: 1410 -1420. First published on March 15, 2007 as 10.2337/db06-0655 [Abstract] [Full Text] [PDF]

Functional Characteristics of Connective Tissue Growth Factor on Vitreoretinal Cells: Takeshi Kita, Yasuaki Hata, Muneki Miura, Shuhei Kawahara, Shintaro Nakao, and Tatsuro Ishibashi
Diabetes 2007 56: 1421 -1428. First published on February 15, 2007 as 10.2337/db06-1644 [Abstract] [Full Text] [PDF]

Glycoprotein Ib ${alpha}$ Polymorphism T145M, Elevated Lipoprotein-Associated Phospholipase A₂, and Hypertriglyceridemia Predict Risk for Recurrent Coronary Events in Diabetic Postinfarction Patients: James P. Corsetti, Dan Ryan, Arthur J. Moss, David L. Rainwater, Wojciech Zareba, and Charles E. Sparks
Diabetes 2007 56: 1429 -1435. First published on February 15, 2007 as 10.2337/db06-1573 [Abstract] [Full Text] [PDF]

Involvement of Heat Shock Factor-1 in Glycated LDL–Induced Upregulation of Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells: Ruozhi Zhao and Garry X. Shen
Diabetes 2007 56: 1436 -1444. First published on January 26, 2007 as 10.2337/db06-1199 [Abstract] [Full Text] [PDF]

Activation of Sphingosine Kinase-1 Mediates Inhibition of Vascular Smooth Muscle Cell Apoptosis by Hyperglycemia: Bei You, Aixia Ren, Guijun Yan, and Jianxin Sun
Diabetes 2007 56: 1445 -1453. First published on February 26, 2007 as 10.2337/db06-1418 [Abstract] [Full Text] [PDF]

Pharmacology and Therapeutics:

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity: Johannes M. Aerts, Roelof Ottenhoff, Andrew S. Powlson, Aldo Grefhorst, Marco van Eijk, Peter F. Dubbelhuis, Jan Aten, Folkert Kuipers, Mireille J. Serlie, Tom Wennekes, Jaswinder K. Sethi, Stephen O'Rahilly, and Hermen S. Overkleeft
Diabetes 2007 56: 1341 -1349. First published on February 7, 2007 as 10.2337/db06-1619 [Abstract] [Full Text] [PDF] Online-Only Appendix

Genetics:

Genetic Deletion of Trb3, the Mammalian Drosophila tribbles Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis: Haruka Okamoto, Esther Latres, Rong Liu, Karen Thabet, Andrew Murphy, David Valenzeula, George D. Yancopoulos, Trevor N. Stitt, David J. Glass, and Mark W. Sleeman
Diabetes 2007 56: 1350 -1356. First published on February 15, 2007 as 10.2337/db06-1448 [Abstract] [Full Text] [PDF] Online Figures

Variants in ARHGEF11, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians: Lijun Ma, Robert L. Hanson, Lorem N. Que, Anna M.G. Cali, Mao Fu, Janel L. Mack, Aniello M. Infante, Sayuko Kobes, the International Type 2 Diabetes 1q Consortium, Clifton Bogardus, Alan R. Shuldiner, and Leslie J. Baier
Diabetes 2007 56: 1454 -1459. First published on February 7, 2007 as 10.2337/db06-0640 [Abstract] [Full Text] [PDF] Online-Only Appendix

Association Studies of BMI and Type 2 Diabetes in the Neuropeptide Y Pathway: A Possible Role for NPY2R as a Candidate Gene for Type 2 Diabetes in Men: Catarina D. Campbell, Helen N. Lyon, James Nemesh, Jared A. Drake, Tiinamaija Tuomi, Daniel Gaudet, Xiaofeng Zhu, Richard S. Cooper, Kristin G. Ardlie, Leif C. Groop, and Joel N. Hirschhorn
Diabetes 2007 56: 1460 -1467. First published on February 26, 2007 as 10.2337/db06-1051 [Abstract] [Full Text] [PDF] Online-Only Appendix

A Functional Variant of the Adipocyte Glycerol Channel Aquaporin 7 Gene Is Associated With Obesity and Related Metabolic Abnormalities: Sabrina Prudente, Elisabetta Flex, Eleonora Morini, Federica Turchi, Daria Capponi, Salvatore De Cosmo, Vittorio Tassi, Valentina Guida, Angelo Avogaro, Franco Folli, Francesca Maiani, Lucia Frittitta, Bruno Dallapiccola, and Vincenzo Trischitta
Diabetes 2007 56: 1468 -1474. First published on March 9, 2007 as 10.2337/db06-1389 [Abstract] [Full Text] [PDF] Online-Only Appendix

Brief Reports:

A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM): Ricard Masia, Diva D. De Leon, Courtney MacMullen, Heather McKnight, Charles A. Stanley, and Colin G. Nichols
Diabetes 2007 56: 1357 -1362. First published on February 22, 2007 as 10.2337/db06-1746 [Abstract] [Full Text] [PDF]

Evidence That Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) on 1q21 is a Type 2 Diabetes Susceptibility Gene in the Old Order Amish: Mao Fu, Mona M. Sabra, Coleen Damcott, Toni I. Pollin, Lijun Ma, Sandra Ott, John C. Shelton, Xiaolian Shi, Laurie Reinhart, Jeffrey O'Connell, Braxton D. Mitchell, Leslie J. Baier, and Alan R. Shuldiner
Diabetes 2007 56: 1363 -1368. First published on March 16, 2007 as 10.2337/db06-1421 [Abstract] [Full Text] [PDF] Online-Only Appendix

Effects of Dipeptidyl Peptidase-4 Inhibition on Gastrointestinal Function, Meal Appearance, and Glucose Metabolism in Type 2 Diabetes: Adrian Vella, Gerlies Bock, Paula D. Giesler, Duane B. Burton, Denise B. Serra, Monica Ligueros Saylan, Beth E. Dunning, James E. Foley, Robert A. Rizza, and Michael Camilleri
Diabetes 2007 56: 1475 -1480. First published on February 15, 2007 as 10.2337/db07-0136 [Abstract] [Full Text] [PDF] Online-Only Appendix

Transcription Factor 7-Like 2 (TCF7L2) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans: Richard M. Watanabe, Hooman Allayee, Anny H. Xiang, Enrique Trigo, Jaana Hartiala, Jean M. Lawrence, and Thomas A. Buchanan
Diabetes 2007 56: 1481 -1485. First published on February 22, 2007 as 10.2337/db06-1682 [Abstract] [Full Text] [PDF] Online-Only Appendix

Metabolism:

Direct Free Fatty Acid Uptake Into Human Adipocytes In Vivo: Relation to Body Fat Distribution: Samyah Shadid, Christina Koutsari, and Michael D. Jensen
Diabetes 2007 56: 1369 -1375. First published on February 7, 2007 as 10.2337/db06-1680 [Abstract] [Full Text] [PDF]

Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients: Douglas E. Befroy, Kitt Falk Petersen, Sylvie Dufour, Graeme F. Mason, Robin A. de Graaf, Douglas L. Rothman, and Gerald I. Shulman
Diabetes 2007 56: 1376 -1381. First published on February 7, 2007 as 10.2337/db06-0783 [Abstract] [Full Text] [PDF]

Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques: Daniel Kaufman, Mary Ann Banerji, Igor Shorman, Eric L.P. Smith, Jeremy D. Coplan, Leonard A. Rosenblum, and John G. Kral
Diabetes 2007 56: 1382 -1386. [Abstract] [Full Text] [PDF]

Pathophysiology:

Ca²⁺/Calmodulin-Dependent Protein Kinase Kinase- ${alpha}$ Regulates Skeletal Muscle Glucose Uptake Independent of AMP-Activated Protein Kinase and Akt Activation: Carol A. Witczak, Nobuharu Fujii, Michael F. Hirshman, and Laurie J. Goodyear
Diabetes 2007 56: 1403 -1409. First published on February 7, 2007 as 10.2337/db06-1230 [Abstract] [Full Text] [PDF] Online-Only Appendix

Errata:

Errata: Diabetes 2007 56: 1486 . [Extract] [Full Text] [PDF]

Online Letters to the Editor:

Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255: Jeffrey S. Stroup
Diabetes 2007 56: e1 . [Extract] [Full Text] [PDF]

Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255: Guenther Boden
Diabetes 2007 56: e2 . [Extract] [Full Text] [PDF]

Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255: J. Karalliedde and G.C. Viberti
Diabetes 2007 56: e3 . [Extract] [Full Text] [PDF]

Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255: Guenther Boden
Diabetes 2007 56: e4 . [Extract] [Full Text] [PDF]