Diabetes -- Table of Contents (February 2008, 57 [2])

Metabolism:

Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat: Sarah Weksler-Zangen, Itamar Raz, Sigurd Lenzen, Anne Jörns, Shira Ehrenfeld, Gail Amir, Andrei Oprescu, Yoram Yagil, Chana Yagil, David H. Zangen, and Nurit Kaiser
Diabetes 2008 57: 279 -287. First published on October 31, 2007 as 10.2337/db07-0520 [Abstract] [Full Text] [PDF] Online-Only Appendix

Insulin Action in the Double Incretin Receptor Knockout Mouse: Julio E. Ayala, Deanna P. Bracy, Tanya Hansotia, Grace Flock, Yutaka Seino, David H. Wasserman, and Daniel J. Drucker
Diabetes 2008 57: 288 -297. First published on October 31, 2007 as 10.2337/db07-0704 [Abstract] [Full Text] [PDF]

25-Hydroxyvitamin D, IGF-1, and Metabolic Syndrome at 45 Years of Age: A Cross-Sectional Study in the 1958 British Birth Cohort: Elina Hyppönen, Barbara J. Boucher, Diane J. Berry, and Chris Power
Diabetes 2008 57: 298 -305. First published on November 14, 2007 as 10.2337/db07-1122 [Abstract] [Full Text] [PDF]

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP: Yong Deuk Kim, Keun-Gyu Park, Yong-Soo Lee, Yun-Yong Park, Don-Kyu Kim, Balachandar Nedumaran, Won Gu Jang, Won-Jea Cho, Joohun Ha, In-Kyu Lee, Chul-Ho Lee, and Hueng-Sik Choi
Diabetes 2008 57: 306 -314. First published on October 1, 2007 as 10.2337/db07-0381 [Abstract] [Full Text] [PDF] Online-Only Appendix

Large GLUT4 Vesicles Are Stationary While Locally and Reversibly Depleted During Transient Insulin Stimulation of Skeletal Muscle of Living Mice: Imaging Analysis of GLUT4–Enhanced Green Fluorescent Protein Vesicle Dynamics: Hans P.M.M. Lauritzen, Henrik Galbo, Josef Brandauer, Laurie J. Goodyear, and Thorkil Ploug
Diabetes 2008 57: 315 -324. First published on October 31, 2007 as 10.2337/db06-1578 [Abstract] [Full Text] [PDF] Online-Only Appendix

Glucagon-Like Peptide-1 Inhibits Blood-Brain Glucose Transfer in Humans: Susanne Lerche, Birgitte Brock, Jørgen Rungby, Hans E. Bøtker, Niels Møller, Anders Rodell, Bo Martin Bibby, Jens J. Holst, Ole Schmitz, and Albert Gjedde
Diabetes 2008 57: 325 -331. First published on November 8, 2007 as 10.2337/db07-1162 [Abstract] [Full Text] [PDF]

Activation of Peroxisome Proliferator–Activated Receptor (PPAR) ${delta}$ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men: Ulf Risérus, Dennis Sprecher, Tony Johnson, Eric Olson, Sandra Hirschberg, Aixue Liu, Zeke Fang, Priti Hegde, Duncan Richards, Leli Sarov-Blat, Jay C. Strum, Samar Basu, Jane Cheeseman, Barbara A. Fielding, Sandy M. Humphreys, Theodore Danoff, Niall R. Moore, Peter Murgatroyd, Stephen O'Rahilly, Pauline Sutton, Tim Willson, David Hassall, Keith N. Frayn, and Fredrik Karpe
Diabetes 2008 57: 332 -339. First published on November 16, 2007 as 10.2337/db07-1318 [Abstract] [Full Text] [PDF] Online-Only Appendix

Mas Deficiency in FVB/N Mice Produces Marked Changes in Lipid and Glycemic Metabolism: Sérgio Henrique S. Santos, Luciana Rodrigues Fernandes, Érica Guilhen Mario, Adaliene Versiani M. Ferreira, Laura Cristina J. Pôrto, Jaqueline Isaura Alvarez-Leite, Leida Maria Botion, Michael Bader, Natalia Alenina, and Robson Augusto S. Santos
Diabetes 2008 57: 340 -347. First published on November 19, 2007 as 10.2337/db07-0953 [Abstract] [Full Text] [PDF]

Signal Transduction:

Fas-Associated Death Receptor Signaling Evoked by Human Amylin in Islet β-Cells: Shaoping Zhang, Hong Liu, Hua Yu, and Garth J.S. Cooper
Diabetes 2008 57: 348 -356. First published on October 31, 2007 as 10.2337/db07-0849 [Abstract] [Full Text] [PDF]

Impaired Insulin-Stimulated Phosphorylation of Akt and AS160 in Skeletal Muscle of Women With Polycystic Ovary Syndrome Is Reversed by Pioglitazone Treatment: Kurt Højlund, Dorte Glintborg, Nicoline R. Andersen, Jesper B. Birk, Jonas T. Treebak, Christian Frøsig, Henning Beck-Nielsen, and Jørgen F.P. Wojtaszewski
Diabetes 2008 57: 357 -366. First published on October 31, 2007 as 10.2337/db07-0706 [Abstract] [Full Text] [PDF]

Obesity Studies:

High Visceral and Low Abdominal Subcutaneous Fat Stores in the Obese Adolescent: A Determinant of an Adverse Metabolic Phenotype: Sara E. Taksali, Sonia Caprio, James Dziura, Sylvie Dufour, Anna M.G. Calí, T. Robin Goodman, Xenophon Papademetris, Tania S. Burgert, Bridget M. Pierpont, Mary Savoye, Melissa Shaw, Aisha A. Seyal, and Ram Weiss
Diabetes 2008 57: 367 -371. First published on October 31, 2007 as 10.2337/db07-0932 [Abstract] [Full Text] [PDF] Online-Only Appendix

Serum Vaspin Concentrations in Human Obesity and Type 2 Diabetes: Byung-Soo Youn, Nora Klöting, Jürgen Kratzsch, Namseok Lee, Ji Woo Park, Eun-Sun Song, Karen Ruschke, Andreas Oberbach, Mathias Fasshauer, Michael Stumvoll, and Matthias Blüher
Diabetes 2008 57: 372 -377. First published on November 8, 2007 as 10.2337/db07-1045 [Abstract] [Full Text] [PDF]

Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis: Vanessa van Harmelen, Anna Eriksson, Gaby Åström, Kerstin Wåhlén, Erik Näslund, Fredrik Karpe, Keith Frayn, Tommy Olsson, Jonas Andersson, Mikel Rydén, and Peter Arner
Diabetes 2008 57: 378 -386. First published on November 19, 2007 as 10.2337/db07-0893 [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Islet Expression of M3 Uncovers a Key Role for Chemokines in the Development and Recruitment of Diabetogenic Cells in NOD Mice: Andrea P. Martin, Marcos G. Grisotto, Claudia Canasto-Chibuque, Steven L. Kunkel, Jonathan S. Bromberg, Glaucia C. Furtado, and Sergio A. Lira
Diabetes 2008 57: 387 -394. First published on November 14, 2007 as 10.2337/db07-1309 [Abstract] [Full Text] [PDF] Online-Only Appendix

Marginal-Zone B-Cells of Nonobese Diabetic Mice Expand With Diabetes Onset, Invade the Pancreatic Lymph Nodes, and Present Autoantigen to Diabetogenic T-Cells: Eliana Mariño, Marcel Batten, Joanna Groom, Stacey Walters, David Liuwantara, Fabienne Mackay, and Shane T. Grey
Diabetes 2008 57: 395 -404. First published on November 19, 2007 as 10.2337/db07-0589 [Abstract] [Full Text] [PDF]

Murine Antithymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time-Dependent Induction of Immunoregulation: Greg Simon, Matthew Parker, Vijayakumar Ramiya, Clive Wasserfall, Yanfei Huang, Damien Bresson, R. Fletcher Schwartz, Martha Campbell-Thompson, Lauren Tenace, Todd Brusko, Song Xue, Abraham Scaria, Michael Lukason, Scott Eisenbeis, John Williams, Michael Clare-Salzler, Desmond Schatz, Bruce Kaplan, Matthias Von Herrath, Karl Womer, and Mark A. Atkinson
Diabetes 2008 57: 405 -414. First published on November 26, 2007 as 10.2337/db06-1384 [Abstract] [Full Text] [PDF] Online-Only Appendix

Islet Studies:

Inhibition of AMP-Activated Protein Kinase Protects Pancreatic β-Cells From Cytokine-Mediated Apoptosis and CD8⁺ T-Cell–Induced Cytotoxicity: Audrey Riboulet-Chavey, Frédérique Diraison, L. Khai Siew, F. Susan Wong, and Guy A. Rutter
Diabetes 2008 57: 415 -423. First published on November 14, 2007 as 10.2337/db07-0993 [Abstract] [Full Text] [PDF]

Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets: Derek K. Hagman, Martin G. Latour, Swarup K. Chakrabarti, Ghislaine Fontes, Julie Amyot, Caroline Tremblay, Meriem Semache, James A. Lausier, Violet Roskens, Raghavendra G. Mirmira, Thomas L. Jetton, and Vincent Poitout
Diabetes 2008 57: 424 -431. First published on November 8, 2007 as 10.2337/db07-1285 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pathophysiology:

Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance: Vijayalakshmi Varma, Aiwei Yao-Borengasser, Angela M. Bodles, Neda Rasouli, Bounleut Phanavanh, Greg T. Nolen, Emily M. Kern, Radhakrishnan Nagarajan, Horace J. Spencer, III, Mi-Jeong Lee, Susan K. Fried, Robert E. McGehee, Jr., Charlotte A. Peterson, and Philip A. Kern
Diabetes 2008 57: 432 -439. First published on December 5, 2007 as 10.2337/db07-0840 [Abstract] [Full Text] [PDF]

Complications:

Increased Glucose Levels Are Associated With Episodic Memory in Nondiabetic Women: Olov Rolandsson, Anna Backeström, Sture Eriksson, Göran Hallmans, and Lars-Göran Nilsson
Diabetes 2008 57: 440 -443. First published on October 31, 2007 as 10.2337/db07-1215 [Abstract] [Full Text] [PDF]

Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia: Rory J. McCrimmon, Margaret Shaw, Xiaoning Fan, Haiying Cheng, Yuyan Ding, Monica C. Vella, Ligang Zhou, Ewan C. McNay, and Robert S. Sherwin
Diabetes 2008 57: 444 -450. First published on October 31, 2007 as 10.2337/db07-0837 [Abstract] [Full Text] [PDF]

Attenuation of Interstitial Fibrosis and Tubular Apoptosis in db/db Transgenic Mice Overexpressing Catalase in Renal Proximal Tubular Cells: Marie-Luise Brezniceanu, Fang Liu, Chih-Chang Wei, Isabelle Chénier, Nicolas Godin, Shao-Ling Zhang, Janos G. Filep, Julie R. Ingelfinger, and John S.D. Chan
Diabetes 2008 57: 451 -459. First published on October 31, 2007 as 10.2337/db07-0013 [Abstract] [Full Text] [PDF]

Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C- ${alpha}$ –Dependent Pathway: Vicki Thallas-Bonke, Suzanne R. Thorpe, Melinda T. Coughlan, Kei Fukami, Felicia Y.T. Yap, Karly C. Sourris, Sally A. Penfold, Leon A. Bach, Mark E. Cooper, and Josephine M. Forbes
Diabetes 2008 57: 460 -469. First published on October 24, 2007 as 10.2337/db07-1119 [Abstract] [Full Text] [PDF]

Attenuation of Counterregulatory Responses to Recurrent Hypoglycemia by Active Thalamic Inhibition: A Mechanism for Hypoglycemia-Associated Autonomic Failure: Ana Maria Arbelaez, William J. Powers, Tom O. Videen, Joseph L. Price, and Philip E. Cryer
Diabetes 2008 57: 470 -475. First published on November 14, 2007 as 10.2337/db07-1329 [Abstract] [Full Text] [PDF]

In Vivo Effects of Insulin and Free Fatty Acids on Matrix Metalloproteinases in Rat Aorta: Guenther Boden, Weiwei Song, Laura Pashko, and Karen Kresge
Diabetes 2008 57: 476 -483. First published on November 19, 2007 as 10.2337/db07-1261 [Abstract] [Full Text] [PDF]

Pharmacology and Therapeutics:

Sphingosine-1-Phosphate Reduces CD4⁺ T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69: Suseela Srinivasan, David T. Bolick, Dmitriy Lukashev, Courtney Lappas, Michail Sitkovsky, Kevin R. Lynch, and Catherine C. Hedrick
Diabetes 2008 57: 484 -493. First published on November 14, 2007 as 10.2337/db07-0855 [Abstract] [Full Text] [PDF]

Genetics:

Association Analysis Indicates That a Variant GATA-Binding Site in the PIK3CB Promoter Is a Cis-Acting Expression Quantitative Trait Locus for This Gene and Attenuates Insulin Resistance in Obese Children: Catherine Le Stunff, Agnès Dechartres, Virginie Mariot, Chantal Lotton, Cecelia Trainor, Emanuele Miraglia Del Giudice, David Meyre, Ivan Bieche, Ingrid Laurendeau, Philippe Froguel, Diana Zelenika, Dani Fallin, Mark Lathrop, Paul-Henri Roméo, and Pierre Bougnères
Diabetes 2008 57: 494 -502. First published on October 31, 2007 as 10.2337/db07-1273 [Abstract] [Full Text] [PDF]

The Type and the Position of HNF1A Mutation Modulate Age at Diagnosis of Diabetes in Patients with Maturity-Onset Diabetes of the Young (MODY)-3: Christine Bellanné-Chantelot, Claire Carette, Jean-Pierre Riveline, René Valéro, Jean-François Gautier, Etienne Larger, Yves Reznik, Pierre-Henri Ducluzeau, Agnès Sola, Agnès Hartemann-Heurtier, Pierre Lecomte, Lucy Chaillous, Marie Laloi-Michelin, Jean-Marie Wilhem, Pierre Cuny, Françoise Duron, Bruno Guerci, Nathalie Jeandidier, Helen Mosnier-Pudar, Michel Assayag, Danièle Dubois-Laforgue, Gilberto Velho, and José Timsit
Diabetes 2008 57: 503 -508. First published on November 14, 2007 as 10.2337/db07-0859 [Abstract] [Full Text] [PDF] Online-Only Appendix

Association of the ATP-Binding Cassette Transporter A1 R230C Variant With Early-Onset Type 2 Diabetes in a Mexican Population: M. Teresa Villarreal-Molina, M. Teresa Flores-Dorantes, Olimpia Arellano-Campos, Marisela Villalobos-Comparan, Maricela Rodríguez-Cruz, Angel Miliar-García, Adriana Huertas-Vazquez, Marta Menjivar, Sandra Romero-Hidalgo, Niels H. Wacher, M. Teresa Tusie-Luna, Miguel Cruz, Carlos A. Aguilar-Salinas, Samuel Canizales-Quinteros, and the Metabolic Study Group
Diabetes 2008 57: 509 -513. First published on November 14, 2007 as 10.2337/db07-0484 [Abstract] [Full Text] [PDF] Online-Only Appendix

A Candidate Type 2 Diabetes Polymorphism Near the HHEX Locus Affects Acute Glucose-Stimulated Insulin Release in European Populations: Results from the EUGENE2 study: Harald Staiger, Alena Stancáková, Jone Zilinskaite, Markku Vänttinen, Torben Hansen, Maria Adelaide Marini, Ann Hammarstedt, Per-Anders Jansson, Giorgio Sesti, Ulf Smith, Oluf Pedersen, Markku Laakso, Norbert Stefan, Andreas Fritsche, and Hans-Ulrich Häring
Diabetes 2008 57: 514 -517. First published on November 26, 2007 as 10.2337/db07-1254 [Abstract] [Full Text] [PDF] Online-Only Appendix

Nephropathy in Type 1 Diabetes Is Diminished in Carriers of HLA-DRB1*04: The Genetics of Kidneys in Diabetes (GoKinD) Study: Suzanne K. Cordovado, Yuan Zhao, James H. Warram, Hongguang Gong, Karen L. Anderson, Miyono M. Hendrix, Laura N. Hancock, Patricia A. Cleary, and Patricia W. Mueller
Diabetes 2008 57: 518 -522. First published on November 26, 2007 as 10.2337/db07-0826 [Abstract] [Full Text] [PDF] Online-Only Appendix

Errata:

Erratum: Diabetes 2008 57: 523 . [Extract] [Full Text] [PDF]

Online Letters to the Editor:

Comment on: Lachin et al. (2007) The Hemoglobin Glycation Index Is Not an Independent Predictor of the Risk of Microvascular Complications in the Diabetes Control and Complications Trial: Diabetes 56:1913–1921, 2007: Stuart Chalew, James Hempe, and Robert McCarter
Diabetes 2008 57: e4 . [Extract] [Full Text] [PDF]

Response to Comment on: Lachin et al. (2007) The Hemoglobin Glycation Index Is Not an Independent Predictor of the Risk of Microvascular Complications in the Diabetes Control and Complications Trial: Diabetes 56:1913–1921, 2007: David M. Nathan, Saul Genuth, Brandy Rutledge, and John Lachin
Diabetes 2008 57: e5 . [Extract] [Full Text] [PDF]