Diabetes -- Table of Contents (March 2008, 57 [3])

Commentaries:

First-Trimester Human Fetal Pancreas Transplantation for Type 1 Diabetes Treatment: An Alternative Approach for Achieving Long-Term Graft Survival?: Georgia Fousteri and Matthias von Herrath
Diabetes 2008 57: 525 -526. [Extract] [Full Text] [PDF]

HLA on Chromosome 6: The Story Gets Longer and Longer: Leslie J. Raffel, Janelle A. Noble, and Jerome I. Rotter
Diabetes 2008 57: 527 -528. [Extract] [Full Text] [PDF]

β-Cell Replication by Loosening the Brakes of Glucagon-Like Peptide-1 Receptor Signaling: Frans C. Schuit and Daniel J. Drucker
Diabetes 2008 57: 529 -531. [Extract] [Full Text] [PDF]

Rho Kinase Inhibition: A New Approach for Treating Diabetic Nephropathy?: Leon A. Bach
Diabetes 2008 57: 532 -533. [Extract] [Full Text] [PDF]

Interaction Between Exercise and Leptin in the Treatment of Obesity: Christopher Morrison
Diabetes 2008 57: 534 -535. [Extract] [Full Text] [PDF]

New Methodologies and Databases:

Retinal Arteriolar Narrowing Predicts Incidence of Diabetes: The Australian Diabetes, Obesity and Lifestyle (AusDiab) Study: Thanh T. Nguyen, Jie Jin Wang, F.M. Amirul Islam, Paul Mitchell, Robyn J. Tapp, Paul Z. Zimmet, Richard Simpson, Jonathan Shaw, and Tien Y. Wong
Diabetes 2008 57: 536 -539. First published on December 17, 2007 as 10.2337/db07-1376 [Abstract] [Full Text] [PDF]

Metabolism:

Insulin Signaling Stimulates Insulin Transport by Bovine Aortic Endothelial Cells: Hong Wang, Aileen X. Wang, Zhenqi Liu, and Eugene J. Barrett
Diabetes 2008 57: 540 -547. First published on October 31, 2007 as 10.2337/db07-0967 [Abstract] [Full Text] [PDF]

The Role of Free-Living Daily Walking in Human Weight Gain and Obesity: James A. Levine, Shelly K. McCrady, Lorraine M. Lanningham-Foster, Paul H. Kane, Randal C. Foster, and Chinmay U. Manohar
Diabetes 2008 57: 548 -554. First published on November 14, 2007 as 10.2337/db07-0815 [Abstract] [Full Text] [PDF] Online-Only Appendix

Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice: Vanessa Tobin, Maude Le Gall, Xavier Fioramonti, Emilie Stolarczyk, Alba G. Blazquez, Christophe Klein, Magali Prigent, Patricia Serradas, Marie-Hélène Cuif, Christophe Magnan, Armelle Leturque, and Edith Brot-Laroche
Diabetes 2008 57: 555 -562. First published on December 5, 2007 as 10.2337/db07-0928 [Abstract] [Full Text] [PDF] Online-Only Appendix

Forkhead Transcription Factor FoxO1 in Adipose Tissue Regulates Energy Storage and Expenditure: Jun Nakae, Yongheng Cao, Miyo Oki, Yasuko Orba, Hirofumi Sawa, Hiroshi Kiyonari, Kristy Iskandar, Koji Suga, Marc Lombes, and Yoshitake Hayashi
Diabetes 2008 57: 563 -576. First published on December 27, 2007 as 10.2337/db07-0698 [Abstract] [Full Text] [PDF] Online-Only Appendix

Signal Transduction:

Resistin Impairs Insulin-Evoked Vasodilation: Maria Teresa Gentile, Carmine Vecchione, Gennaro Marino, Alessandra Aretini, Alba Di Pardo, Giovanna Antenucci, Angelo Maffei, Giuseppe Cifelli, Luca Iorio, Alessandro Landolfi, Giacomo Frati, and Giuseppe Lembo
Diabetes 2008 57: 577 -583. First published on December 7, 2007 as 10.2337/db07-0557 [Abstract] [Full Text] [PDF]

Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator- ${alpha}$ and DUSP14: Sonia Klinger, Carine Poussin, Marie-Bernard Debril, Wanda Dolci, Philippe A. Halban, and Bernard Thorens
Diabetes 2008 57: 584 -593. First published on November 19, 2007 as 10.2337/db07-1414 [Abstract] [Full Text] [PDF] Online-Only Appendix

Obesity Studies:

A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet–Induced Weight Loss: Eduardo R. Ropelle, José R. Pauli, Maria Fernanda A. Fernandes, Silvana A. Rocco, Rodrigo M. Marin, Joseane Morari, Kellen K. Souza, Marília M. Dias, Maria C. Gomes-Marcondes, José A.R. Gontijo, Kleber G. Franchini, Lício A. Velloso, Mario J.A. Saad, and José B.C. Carvalheira
Diabetes 2008 57: 594 -605. First published on December 5, 2007 as 10.2337/db07-0573 [Abstract] [Full Text] [PDF]

Increased Skeletal Muscle Tumor Necrosis Factor- ${alpha}$ and Impaired Insulin Signaling Persist in Obese Women With Gestational Diabetes Mellitus 1 Year Postpartum: Jacob E. Friedman, John P. Kirwan, Ming Jing, Larraine Presley, and Patrick M. Catalano
Diabetes 2008 57: 606 -613. First published on December 14, 2007 as 10.2337/db07-1356 [Abstract] [Full Text] [PDF]

Synergy Between Leptin Therapy and a Seemingly Negligible Amount of Voluntary Wheel Running Prevents Progression of Dietary Obesity in Leptin-Resistant Rats: Alexandra Shapiro, Michael Matheny, Yi Zhang, Nihal Tümer, Kit-Yan Cheng, Enda Rogrigues, Sergei Zolotukhin, and Philip J. Scarpace
Diabetes 2008 57: 614 -622. First published on December 17, 2007 as 10.2337/db07-0863 [Abstract] [Full Text] [PDF]

Evidence of an Influence of a Polymorphism Near the INSIG2 on Weight Loss During a Lifestyle Intervention in Obese Children and Adolescents: Thomas Reinehr, Anke Hinney, Thuy Trang Nguyen, and Johannes Hebebrand
Diabetes 2008 57: 623 -626. First published on November 14, 2007 as 10.2337/db07-0408 [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Reduced Immunogenicity of First-Trimester Human Fetal Pancreas: Kerstin Brands, Emily Colvin, Lindy J. Williams, Rennian Wang, Richard B. Lock, and Bernard E. Tuch
Diabetes 2008 57: 627 -634. First published on December 7, 2007 as 10.2337/db07-0720a [Abstract] [Full Text] [PDF] Online-Only Appendix

Islet Studies:

The Repression of IRS2 Gene by ATF3, a Stress-Inducible Gene, Contributes to Pancreatic β-Cell Apoptosis: Dan Li, Xin Yin, Erik J. Zmuda, Christopher C. Wolford, Xiaocheng Dong, Morris F. White, and Tsonwin Hai
Diabetes 2008 57: 635 -644. First published on December 5, 2007 as 10.2337/db07-0717 [Abstract] [Full Text] [PDF] Online-Only Appendix

Transcription Factor 7-Like 2 Regulates β-Cell Survival and Function in Human Pancreatic Islets: Luan Shu, Nadine S. Sauter, Fabienne T. Schulthess, Aleksey V. Matveyenko, José Oberholzer, and Kathrin Maedler
Diabetes 2008 57: 645 -653. First published on December 10, 2007 as 10.2337/db07-0847 [Abstract] [Full Text] [PDF]

Defining Pancreatic Endocrine Precursors and Their Descendants: Peter White, Catherine Lee May, Rodrigo N. Lamounier, John E. Brestelli, and Klaus H. Kaestner
Diabetes 2008 57: 654 -668. First published on December 10, 2007 as 10.2337/db07-1362 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pathophysiology:

Postnatal Programming of Glucocorticoid Metabolism in Rats Modulates High-Fat Diet–Induced Regulation of Visceral Adipose Tissue Glucocorticoid Exposure and Sensitivity and Adiponectin and Proinflammatory Adipokines Gene Expression in Adulthood: Sandrine Boullu-Ciocca, Vincent Achard, Virginie Tassistro, Anne Dutour, and Michel Grino
Diabetes 2008 57: 669 -677. First published on December 5, 2007 as 10.2337/db07-1316 [Abstract] [Full Text] [PDF]

Predictors of Incretin Concentrations in Subjects With Normal, Impaired, and Diabetic Glucose Tolerance: Kirsten Vollmer, Jens J. Holst, Birgit Baller, Mark Ellrichmann, Michael A. Nauck, Wolfgang E. Schmidt, and Juris J. Meier
Diabetes 2008 57: 678 -687. First published on December 5, 2007 as 10.2337/db07-1124 [Abstract] [Full Text] [PDF]

The Effect of Cyclooxygenase-2 Inhibition on Renal Hemodynamic Function in Humans With Type 1 Diabetes: David Z.I. Cherney, Judith A. Miller, James W. Scholey, Timothy J. Bradley, Cameron Slorach, Jaqueline R. Curtis, Maria G. Dekker, Rania Nasrallah, Richard L. Hébert, and Etienne B. Sochett
Diabetes 2008 57: 688 -695. First published on December 14, 2007 as 10.2337/db07-1230 [Abstract] [Full Text] [PDF]

Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK-eNOS–Mediated Signaling: John W. Calvert, Susheel Gundewar, Saurabh Jha, James J.M. Greer, William H. Bestermann, Rong Tian, and David J. Lefer
Diabetes 2008 57: 696 -705. First published on December 14, 2007 as 10.2337/db07-1098 [Abstract] [Full Text] [PDF]

Protein Kinase C ${theta}$ Activation Induces Insulin-Mediated Constriction of Muscle Resistance Arteries: Wineke Bakker, Pieter Sipkema, Coen D.A. Stehouwer, Erik H. Serne, Yvo M. Smulders, Victor W.M. van Hinsbergh, and Etto C. Eringa
Diabetes 2008 57: 706 -713. First published on December 17, 2007 as 10.2337/db07-0792 [Abstract] [Full Text] [PDF] Online-Only Appendix

Complications:

Targeting of RhoA/ROCK Signaling Ameliorates Progression of Diabetic Nephropathy Independent of Glucose Control: Vasantha Kolavennu, Lixia Zeng, Hui Peng, Yin Wang, and Farhad R. Danesh
Diabetes 2008 57: 714 -723. First published on December 14, 2007 as 10.2337/db07-1241 [Abstract] [Full Text] [PDF]

In Vitro Hyperglycemia or a Diabetic Intrauterine Environment Reduces Neonatal Endothelial Colony-Forming Cell Numbers and Function: David A. Ingram, Izlin Z. Lien, Laura E. Mead, Myka Estes, Daniel N. Prater, Ethel Derr-Yellin, Linda A. DiMeglio, and Laura S. Haneline
Diabetes 2008 57: 724 -731. First published on December 17, 2007 as 10.2337/db07-1507 [Abstract] [Full Text] [PDF]

Delayed Recovery of Cognitive Function Following Hypoglycemia in Adults With Type 1 Diabetes: Effect of Impaired Awareness of Hypoglycemia: Nicola N. Zammitt, Roderick E. Warren, Ian J. Deary, and Brian M. Frier
Diabetes 2008 57: 732 -736. First published on November 26, 2007 as 10.2337/db07-0695 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pharmacology and Therapeutics:

Therapeutic Potential of Peroxisome Proliferators–Activated Receptor- ${alpha}$ / ${gamma}$ Dual Agonist With Alleviation of Endoplasmic Reticulum Stress for the Treatment of Diabetes: Kyu Lee Han, Joo Sun Choi, Jae Young Lee, Jihyun Song, Myung Kuk Joe, Myeong Ho Jung, and Jae-Kwan Hwang
Diabetes 2008 57: 737 -745. First published on December 7, 2007 as 10.2337/db07-0972 [Abstract] [Full Text] [PDF] Online-Only Appendix

Different Brain Responses to Hypoglycemia Induced by Equipotent Doses of the Long-Acting Insulin Analog Detemir and Human Regular Insulin in Humans: Paolo Rossetti, Francesca Porcellati, Natalia Busciantella Ricci, Paola Candeloro, Patrizia Cioli, Geremia B. Bolli, and Carmine G. Fanelli
Diabetes 2008 57: 746 -756. First published on December 14, 2007 as 10.2337/db07-1433 [Abstract] [Full Text] [PDF]

Reversal of Streptozotocin-Induced Diabetes in Mice by Cellular Transduction With Recombinant Pancreatic Transcription Factor Pancreatic Duodenal Homeobox-1: A Novel Protein Transduction Domain–Based Therapy: Vijay Koya, Shun Lu, Yu-Ping Sun, Daniel L. Purich, Mark A. Atkinson, Shi-Wu Li, and Li-Jun Yang
Diabetes 2008 57: 757 -769. First published on December 17, 2007 as 10.2337/db07-1441 [Abstract] [Full Text] [PDF]

Genetics:

Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility Complex: Theresa A. Aly, Erin E. Baschal, Mohamed M. Jahromi, Maria S. Fernando, Sunanda R. Babu, Tasha E. Fingerlin, Adam Kretowski, Henry A. Erlich, Pamela R. Fain, Marian J. Rewers, and George S. Eisenbarth
Diabetes 2008 57: 770 -776. First published on December 7, 2007 as 10.2337/db07-0900 [Abstract] [Full Text] [PDF] Online-Only Appendix

Genetic Variation and Association Analyses of the Nuclear Respiratory Factor 1 (nRF1) Gene in Chinese Patients With Type 2 Diabetes: Yang Liu, Nifang Niu, Xilin Zhu, Te Du, Xin Wang, Dongmei Chen, Xiaopan Wu, Harvest F. Gu, and Ying Liu
Diabetes 2008 57: 777 -782. First published on December 10, 2007 as 10.2337/db07-0008 [Abstract] [Full Text] [PDF]

Identification and Replication of a Novel Obesity Locus on Chromosome 1q24 in Isolated Populations of Cilento: Marina Ciullo, Teresa Nutile, Cyril Dalmasso, Rossella Sorice, Céline Bellenguez, Vincenza Colonna, Maria Graziella Persico, and Catherine Bourgain
Diabetes 2008 57: 783 -790. First published on December 27, 2007 as 10.2337/db07-0970 [Abstract] [Full Text] [PDF]

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 With Susceptibility to Type 2 Diabetes in a Japanese Population: Shintaro Omori, Yasushi Tanaka, Atsushi Takahashi, Hiroshi Hirose, Atsunori Kashiwagi, Kohei Kaku, Ryuzo Kawamori, Yusuke Nakamura, and Shiro Maeda
Diabetes 2008 57: 791 -795. First published on December 27, 2007 as 10.2337/db07-0979 [Abstract] [Full Text] [PDF] Online-Only Appendix

Online Letters to the Editor:

Comment on: Tritt et al. (2007) Functional Waning of Naturally Occurring CD4⁺ Regulatory T-cells Contributes to the Onset of Autoimmune Diabetes: Diabetes 57:113–123, 2007: David C. Thomas, Richard J. Mellanby, and Anne Cooke
Diabetes 2008 57: e6 . [Extract] [Full Text] [PDF]

Response to Comment on: Tritt et al. (2007) Functional Waning of Naturally Occurring CD4⁺ Regulatory T-Cells Contributes to the Onset of Autoimmune Diabetes: Diabetes 57:113–123, 2007: Michael Tritt, Evridiki Sgouroudis, Eva d’Hennezel, Alexandre Albanese, and Ciriaco A. Piccirillo
Diabetes 2008 57: e7 -e8. [Extract] [Full Text] [PDF]