Diabetes -- Table of Contents (June 2008, 57 [6])

Perspectives in Diabetes:

From Fibrosis to Sclerosis: Mechanisms of Glomerulosclerosis in Diabetic Nephropathy: Ying Qian, Eva Feldman, Subramanian Pennathur, Matthias Kretzler, and Frank C. Brosius, III
Diabetes 2008 57: 1439 -1445. [Extract] [Full Text] [PDF]

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes: Josephine M. Forbes, Melinda T. Coughlan, and Mark E. Cooper
Diabetes 2008 57: 1446 -1454. [Abstract] [Full Text] [PDF]

Commentaries:

Fatty Acid Oxidation and Insulin Action: When Less Is More: Deborah M. Muoio and Christopher B. Newgard
Diabetes 2008 57: 1455 -1456. [Extract] [Full Text] [PDF]

Dedifferentiation for Replication of Human β-Cells: A Division Between Mice and Men?: Nils Billestrup and Timo Otonkoski
Diabetes 2008 57: 1457 -1458. [Extract] [Full Text] [PDF]

Smad1 as a Biomarker for Diabetic Nephropathy: Hideki Kato, Han Si, Thomas Hostetter, and Katalin Susztak
Diabetes 2008 57: 1459 -1460. [Extract] [Full Text] [PDF]

HNF4A and Diabetes: Injury Before Insult?: Ben Z. Stanger
Diabetes 2008 57: 1461 -1462. [Extract] [Full Text] [PDF]

Metabolism:

Interaction of Oral Antidiabetic Drugs With Hepatic Uptake Transporters: Focus on Organic Anion Transporting Polypeptides and Organic Cation Transporter 1: Iouri Bachmakov, Hartmut Glaeser, Martin F. Fromm, and Jörg König
Diabetes 2008 57: 1463 -1469. First published on February 26, 2008 as 10.2337/db07-1515 [Abstract] [Full Text] [PDF]

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice: Patrice D. Cani, Rodrigo Bibiloni, Claude Knauf, Aurélie Waget, Audrey M. Neyrinck, Nathalie M. Delzenne, and Rémy Burcelin
Diabetes 2008 57: 1470 -1481. First published on February 27, 2008 as 10.2337/db07-1403 [Abstract] [Full Text] [PDF] Online-Only Appendix

Central Nervous System Neuropeptide Y Signaling Modulates VLDL Triglyceride Secretion: John M. Stafford, Fang Yu, Richard Printz, Alyssa H. Hasty, Larry L. Swift, and Kevin D. Niswender
Diabetes 2008 57: 1482 -1490. First published on March 10, 2008 as 10.2337/db07-1702 [Abstract] [Full Text] [PDF] Figures

Kinin B₁ Receptor Deficiency Leads to Leptin Hypersensitivity and Resistance to Obesity: Marcelo A. Mori, Ronaldo C. Araújo, Felipe C.G. Reis, Daniela G. Sgai, Raphael G. Fonseca, Carlos C. Barros, Vanessa F. Merino, Mariana Passadore, Ana M. Barbosa, Bernard Ferrari, Pierre Carayon, Charlles H.M. Castro, Suma I. Shimuta, Jacqueline Luz, Jean-Loup Bascands, Joost P. Schanstra, Patrick C. Even, Suzana M. Oliveira, Michael Bader, and João B. Pesquero
Diabetes 2008 57: 1491 -1500. First published on March 10, 2008 as 10.2337/db07-1508 [Abstract] [Full Text] [PDF] Online-Only Appendix

Metformin Decreases the Adipokine Vaspin in Overweight Women With Polycystic Ovary Syndrome Concomitant With Improvement in Insulin Sensitivity and a Decrease in Insulin Resistance: Bee K. Tan, Dennis Heutling, Jing Chen, S. Farhatullah, Raghu Adya, Stephen D. Keay, C. Richard Kennedy, Hendrik Lehnert, and Harpal S. Randeva
Diabetes 2008 57: 1501 -1507. First published on March 28, 2008 as 10.2337/db08-0127 [Abstract] [Full Text] [PDF]

Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle: Karim Bouzakri, Reginald Austin, Anna Rune, Michael E. Lassman, Pablo M. Garcia-Roves, Joel P. Berger, Anna Krook, Alexander V. Chibalin, Bei B. Zhang, and Juleen R. Zierath
Diabetes 2008 57: 1508 -1516. First published on February 26, 2008 as 10.2337/db07-0583 [Abstract] [Full Text] [PDF] Figures

Obesity Studies:

Transgenic Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons: A Novel Model of Increased Adiposity and Impaired Glucose Tolerance: Suvi T. Ruohonen, Ullamari Pesonen, Niko Moritz, Katja Kaipio, Matias Röyttä, Markku Koulu, and Eriika Savontaus
Diabetes 2008 57: 1517 -1525. First published on February 14, 2008 as 10.2337/db07-0722 [Abstract] [Full Text] [PDF]

Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance: Ming Li, Dong Hyun Kim, Peter L. Tsenovoy, Stephen J. Peterson, Rita Rezzani, Luigi F. Rodella, Wilbert S. Aronow, Susumu Ikehara, and Nader G. Abraham
Diabetes 2008 57: 1526 -1535. First published on March 28, 2008 as 10.2337/db07-1764 [Abstract] [Full Text] [PDF] Figures

Reduced Glucocorticoid Production Rate, Decreased 5 ${alpha}$ -Reductase Activity, and Adipose Tissue Insulin Sensitization After Weight Loss: Jeremy W. Tomlinson, Joanne Finney, Beverly A. Hughes, Susan V. Hughes, and Paul M. Stewart
Diabetes 2008 57: 1536 -1543. First published on March 13, 2008 as 10.2337/db08-0094 [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

A Microsphere-Based Vaccine Prevents and Reverses New-Onset Autoimmune Diabetes: Brett Phillips, Karen Nylander, Jo Harnaha, Jennifer Machen, Robert Lakomy, Alexis Styche, Kimberly Gillis, Larry Brown, Debra Lafreniere, Michael Gallo, Janet Knox, Kenneth Hogeland, Massimo Trucco, and Nick Giannoukakis
Diabetes 2008 57: 1544 -1555. First published on March 3, 2008 as 10.2337/db07-0507 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Caspase Selective Inhibitor EP1013 Augments Human Islet Graft Function and Longevity in Marginal Mass Islet Transplantation in Mice: Juliet A. Emamaullee, Joy Davis, Rena Pawlick, Christian Toso, Shaheed Merani, Sui-Xiong Cai, Ben Tseng, and A.M. James Shapiro
Diabetes 2008 57: 1556 -1566. First published on March 20, 2008 as 10.2337/db07-1452 [Abstract] [Full Text] [PDF]

Intrahepatic Glucose Flux as a Mechanism for Defective Intrahepatic Islet ${alpha}$ -Cell Response to Hypoglycemia: Huarong Zhou, Tao Zhang, Marika Bogdani, Elizabeth Oseid, Susan Parazzoli, Marie-Christine Vantyghem, Jamie Harmon, Michela Slucca, and R. Paul Robertson
Diabetes 2008 57: 1567 -1574. First published on March 24, 2008 as 10.2337/db08-0137 [Abstract] [Full Text] [PDF]

Islet Studies:

In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing: Holger A. Russ, Yael Bar, Philippe Ravassard, and Shimon Efrat
Diabetes 2008 57: 1575 -1583. First published on March 3, 2008 as 10.2337/db07-1283 [Abstract] [Full Text] [PDF] Online-Only Appendix

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans: Juris J. Meier, Alexandra E. Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A. Rizza, and Peter C. Butler
Diabetes 2008 57: 1584 -1594. First published on March 11, 2008 as 10.2337/db07-1369 [Abstract] [Full Text] [PDF]

A Rare Mutation in ABCC8/SUR1 Leading to Altered ATP-Sensitive K⁺ Channel Activity and β-Cell Glucose Sensing Is Associated With Type 2 Diabetes in Adults: Andrei I. Tarasov, Tamara J. Nicolson, Jean-Pierre Riveline, Tarvinder K. Taneja, Stephen A. Baldwin, Jocelyn M. Baldwin, Guillaume Charpentier, Jean-François Gautier, Philippe Froguel, Martine Vaxillaire, and Guy A. Rutter
Diabetes 2008 57: 1595 -1604. First published on March 17, 2008 as 10.2337/db07-1547 [Abstract] [Full Text] [PDF] Online-Only Appendix

Critical Roles for Macrophages in Islet Angiogenesis and Maintenance During Pancreatic Degeneration: Jeffery S. Tessem, Jan N. Jensen, Hanna Pelli, Xu-Ming Dai, Xiao-Hua Zong, E. Richard Stanley, Jan Jensen, and James DeGregori
Diabetes 2008 57: 1605 -1617. First published on March 28, 2008 as 10.2337/db07-1577 [Abstract] [Full Text] [PDF] Online-Only Appendix

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion: Matthias Braun, Reshma Ramracheya, Martin Bengtsson, Quan Zhang, Jovita Karanauskaite, Chris Partridge, Paul R. Johnson, and Patrik Rorsman
Diabetes 2008 57: 1618 -1628. First published on April 4, 2008 as 10.2337/db07-0991 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pathophysiology:

Elevated Epidermal Growth Factor Receptor Phosphorylation Induces Resistance Artery Dysfunction in Diabetic db/db Mice: Souad Belmadani, Desiree I. Palen, Romer A. Gonzalez-Villalobos, Hamid A. Boulares, and Khalid Matrougui
Diabetes 2008 57: 1629 -1637. First published on March 4, 2008 as 10.2337/db07-0739 [Abstract] [Full Text] [PDF]

β-Cell Dysfunction in Subjects With Impaired Glucose Tolerance and Early Type 2 Diabetes: Comparison of Surrogate Markers With First-Phase Insulin Secretion From an Intravenous Glucose Tolerance Test: Andreas Festa, Ken Williams, Anthony J.G. Hanley, and Steven M. Haffner
Diabetes 2008 57: 1638 -1644. First published on March 10, 2008 as 10.2337/db07-0954 [Abstract] [Full Text] [PDF]

Retinal and Cerebral Microvascular Signs and Diabetes: The Age, Gene/Environment Susceptibility-Reykjavik Study: Chengxuan Qiu, Mary Frances Cotch, Sigurdur Sigurdsson, Melissa Garcia, Ronald Klein, Fridbert Jonasson, Barbara E.K. Klein, Gudny Eiriksdottir, Tamara B. Harris, Mark A. van Buchem, Vilmundur Gudnason, and Lenore J. Launer
Diabetes 2008 57: 1645 -1650. First published on March 10, 2008 as 10.2337/db07-1455 [Abstract] [Full Text] [PDF]

Suppressors of Cytokine-Signaling Proteins Induce Insulin Resistance in the Retina and Promote Survival of Retinal Cells: Xuebin Liu, Marie G. Mameza, Yun Sang Lee, Chikezie I. Eseonu, Cheng-Rong Yu, Jennifer J. Kang Derwent, and Charles E. Egwuagu
Diabetes 2008 57: 1651 -1658. First published on March 20, 2008 as 10.2337/db07-1761 [Abstract] [Full Text] [PDF] Online-Only Appendix Online-Only Appendix

Persistent Hyperinsulinemic Hypoglycemia and Maturity-Onset Diabetes of the Young Due to Heterozygous HNF4A Mutations: Ritika R. Kapoor, Jonathan Locke, Kevin Colclough, Jerry Wales, Jennifer J. Conn, Andrew T. Hattersley, Sian Ellard, and Khalid Hussain
Diabetes 2008 57: 1659 -1663. First published on February 11, 2008 as 10.2337/db07-1657 [Abstract] [Full Text] [PDF]

Complications:

Distal Degenerative Sensory Neuropathy in a Long-Term Type 2 Diabetes Rat Model: Valentine Brussee, GuiFang Guo, YingYing Dong, Chu Cheng, José A. Martinez, Darrell Smith, Gordon W. Glazner, Paul Fernyhough, and Douglas W. Zochodne
Diabetes 2008 57: 1664 -1673. First published on March 10, 2008 as 10.2337/db07-1737 [Abstract] [Full Text] [PDF]

Decreased Lipoprotein Clearance Is Responsible for Increased Cholesterol in LDL Receptor Knockout Mice With Streptozotocin-Induced Diabetes: Ira J. Goldberg, Yunying Hu, Hye-Lim Noh, Justin Wei, Lesley Ann Huggins, Marnie G. Rackmill, Hiroko Hamai, Brendan N. Reid, William S. Blaner, and Li-Shin Huang
Diabetes 2008 57: 1674 -1682. First published on March 17, 2008 as 10.2337/db08-0083 [Abstract] [Full Text] [PDF]

RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease: Fangfang Peng, Dongcheng Wu, Bo Gao, Alistair J. Ingram, Baifang Zhang, Katherine Chorneyko, Rick McKenzie, and Joan C. Krepinsky
Diabetes 2008 57: 1683 -1692. First published on March 20, 2008 as 10.2337/db07-1149 [Abstract] [Full Text] [PDF]

Abnormal Muscle Spindle Innervation and Large-Fiber Neuropathy in Diabetic Mice: Karra A. Muller, Janelle M. Ryals, Eva L. Feldman, and Douglas E. Wright
Diabetes 2008 57: 1693 -1701. First published on March 24, 2008 as 10.2337/db08-0022 [Abstract] [Full Text] [PDF]

Haptoglobin Genotype: A Determinant of Cardiovascular Complication Risk in Type 1 Diabetes: Tina Costacou, Robert E. Ferrell, and Trevor J. Orchard
Diabetes 2008 57: 1702 -1706. First published on March 10, 2008 as 10.2337/db08-0095 [Abstract] [Full Text] [PDF]

Having One Kidney Does Not Accelerate the Rate of Development of Diabetic Nephropathy Lesions in Type 1 Diabetic Patients: Shirley Chang, M. Luiza Caramori, Rika Moriya, and Michael Mauer
Diabetes 2008 57: 1707 -1711. First published on March 28, 2008 as 10.2337/db07-1610 [Abstract] [Full Text] [PDF]

Urinary Smad1 Is a Novel Marker to Predict Later Onset of Mesangial Matrix Expansion in Diabetic Nephropathy: Akira Mima, Hidenori Arai, Takeshi Matsubara, Hideharu Abe, Kojiro Nagai, Yukinori Tamura, Kazuo Torikoshi, Makoto Araki, Hiroshi Kanamori, Toshikazu Takahashi, Tatsuya Tominaga, Motokazu Matsuura, Noriyuki Iehara, Atsushi Fukatsu, Toru Kita, and Toshio Doi
Diabetes 2008 57: 1712 -1722. First published on February 19, 2008 as 10.2337/db07-1726 [Abstract] [Full Text] [PDF] Online-Only Appendix

Pharmacology and Therapeutics:

Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats: Songping Han, Deborah L. Hagan, Joseph R. Taylor, Li Xin, Wei Meng, Scott A. Biller, John R. Wetterau, William N. Washburn, and Jean M. Whaley
Diabetes 2008 57: 1723 -1729. First published on March 20, 2008 as 10.2337/db07-1472 [Abstract] [Full Text] [PDF] Online-Only Appendix

Genetics:

PTPN22 Trp⁶²⁰ Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes: Deborah J. Smyth, Jason D. Cooper, Joanna M.M. Howson, Neil M. Walker, Vincent Plagnol, Helen Stevens, David G. Clayton, and John A. Todd
Diabetes 2008 57: 1730 -1737. First published on February 27, 2008 as 10.2337/db07-1131 [Abstract] [Full Text] [PDF] Online-Only Appendix adfcda

Common Variants in Maturity-Onset Diabetes of the Young Genes and Future Risk of Type 2 Diabetes: Johan Holmkvist, Peter Almgren, Valeriya Lyssenko, Cecilia M. Lindgren, Karl-Fredrik Eriksson, Bo Isomaa, Tiinamaija Tuomi, Peter Nilsson, and Leif Groop
Diabetes 2008 57: 1738 -1744. First published on March 10, 2008 as 10.2337/db06-1464 [Abstract] [Full Text] [PDF] Online-Only Appendix

The Diabetic Phenotype in HNF4A Mutation Carriers Is Moderated By the Expression of HNF4A Isoforms From the P1 Promoter During Fetal Development: Lorna W. Harries, Jonathan M. Locke, Beverley Shields, Neil A. Hanley, Karen Piper Hanley, Anna Steele, Pål R. Njølstad, Sian Ellard, and Andrew T. Hattersley
Diabetes 2008 57: 1745 -1752. First published on March 20, 2008 as 10.2337/db07-1742 [Abstract] [Full Text] [PDF]

Sequencing-Based Genotyping and Association Analysis of the MICA and MICB Genes in Type 1 Diabetes: Sarah F. Field, Sergey Nejentsev, Neil M. Walker, Joanna M.M. Howson, Lisa M. Godfrey, Jennifer D. Jolley, Matthew P.A. Hardy, and John A. Todd
Diabetes 2008 57: 1753 -1756. First published on March 10, 2008 as 10.2337/db07-1402 [Abstract] [Full Text] [PDF] Online-Only Appenidx

Errata:

Lai CQ, Tucker KL, Parnell LD, Adiconis X, García-Bailo B, Griffith J, Meydani M, Ordovás JM: PPARGC1A (PGC-1 ${alpha}$ ) variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes 57:1–8, 2008: Diabetes 2008 57: 1757 . [Extract] [Full Text] [PDF]

Online Letters to the Editor:

Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C- ${alpha}$ –Dependent Pathway: Diabetes 57:460–469, 2008: Sho-ichi Yamagishi
Diabetes 2008 57: e13 . [Extract] [Full Text] [PDF]

Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C- ${alpha}$ –Dependent Pathway: Diabetes 57:460–469, 2008: Vicki Thallas-Bonke and Josephine M. Forbes
Diabetes 2008 57: e14 . [Extract] [Full Text] [PDF]