Table 1

Whole body composition by QMR scan

Pretreatment
fat mass (g)Posttreatment
fat mass (g)ΔFat mass (g)
ZDF vehicle85.3 ± 1.085.7 ± 1.60.4 ± 1.8
Insulin83.9 ± 1.9100.3 ± 2.4***16.5 ± 1.6***
S59782.7 ± 1.994.4 ± 2.3*11.7 ± 1.1***
  • Rats from study B were scanned on the day prior to treatment and again on the day prior to euthanization. Values are expressed as mean ± SEM.

  • *P < 0.05 as compared with ZDF vehicle (one-way ANOVA with Bonferroni posttests).

  • ***P < 0.001 as compared with ZDF vehicle (one-way ANOVA with Bonferroni posttests).