Table 1

Effect of HF diet on plasma and tissue biochemistry in BL6 male mice

9 days30 days
RDHFRDHF
Visceral fat/body weight (%)1.2 ± 0.11.9 ± 0.1*1.4 ± 0.33.8 ± 0.4*
Fasting plasma
 NEFA (mEq/L)0.5 ± 0.10.7 ± 0.10.5 ± 0.11.0 ± 0.1*
 Insulin (pmol/L)36.2 ± 0.7239.9 ± 1.0435.6 ± 1.6659.8 ± 5.84*
 C-peptide (pmol/L)266. ± 34.0277. ± 22.0307. ± 53.2351. ± 39.8
 C-peptide–to–insulin molar ratio8.0 ± 0.27.0 ± 0.19.0 ± 0.15.1 ± 0.0*
Hepatic triacylglycerol (µg/mg protein)183. ± 23.8312. ± 67.6166. ± 21.1688. ± 128.*
Blood glucose (mg/dL)
 Fasting 100. ± 2.10104. ± 5.6096.5 ± 5.90111. ± 7.00
 Fed 101. ± 5.31108. ± 7.02103. ± 4.41136. ± 14.9*
  • Mice (4 months of age, n > 6 per feeding group) were fed RD or HF for 9 or 30 days. Values are expressed as mean ± SEM.

  • *P < 0.05 HF vs. RD per feeding period.