TABLE 2

RR of type 2 diabetes in relation to average daily alcohol intake: the Health Professionals Follow-Up Study, 1986–1998

Alcohol intake (g/day)Cases (n)Person-yearsRR*
Age and BMI adjustedMultivariate analysis 1Multivariate analysis 2
0416115,646Reference groupReference group
0.1–4.9450123,2371.09 (0.95–1.24)1.05 (0.92–1.20)Reference group
5.0–9.921475,3310.88 (0.74–1.04)0.80 (0.68–0.95)0.75 (0.63–0.89)
10.0–14.916365,6570.77 (0.64–0.92)0.71 (0.59–0.86)0.65 (0.54–0.79)
15.0–29.917468,5980.80 (0.67–0.96)0.64 (0.53–0.78)0.61 (0.50–0.74)
30.0–49.911645,0300.72 (0.58–0.88)0.57 (0.45–0.71)0.53 (0.42–0.67)
≥50.03815,4030.64 (0.46–0.89)0.61 (0.43–0.86)0.55 (0.39–0.79)
P<0.0001<0.0001<0.0001
  • *

    * Data are RR (95% CI). In multivariate analysis 1, abstainers used as reference group. RR controlled for age and BMI (seven categories each); smoking (pack-years: six categories); physical activity level; quintiles of dietary glycemic load, fiber, trans-fats and polyunsaturated fats, all energy adjusted; profession; history of diagnosed hypertension, hypercholesterolemia, coronary heart disease, or cancer; and family history of type 2 diabetes. In multivariate analysis 2, only current drinkers included, with light drinkers (0.1–4.9 g/day) used as reference group. RR adjusted for all covariates in analysis 1.