TABLE 2

Quantitative genetic univariate model–fitting results for HbA1c levels in healthy twins

ModelsA2 (95%CI)C2/D2 (95%CI)E2 (95% CI)Age2 (95% CI)χ2dfΔχ2vs.ΔdfP
A-D-E0.62 (0.00–0.75)0.00 (0.00–0.68)0.23 (0.15–0.36)0.14 (0.05–0.28)6.617
A-C-E0.50 (0.09–0.75)0.13 (0.00–0.47)0.24 (0.15–0.38)0.14 (0.05–0.28)6.267
A-C-E no age0.50 (0.08–0.84)0.28 (0.00–0.62)0.24 (0.15–0.39)23.29817.03A-C-E1<0.001
A-E0.62 (0.47–0.75)0.23 (0.15–0.36)0.14 (0.05–0.28)6.6180.35A-C-E10.55
C-E0.49 (0.34–0.63)0.36 (0.26–0.51)0.14 (0.04–0.28)12.0485.78A-C-E10.016
  • Note: AE is the best fitting model. Age2, variance component due to age; Δχ2 = χ2 (submodel) − χ2 (full model); Δdf = df (submodel) − df (full model); vs., versus and indicates with which full model the submodel is compared.