TABLE 1

Body composition and fat distribution of aging rats


young
SO
SC
VF
CR
n66868
VF/SC removed (g)0014.9 ± 1.715.7 ± 1.30
Body weight (g)291 ± 13478 ± 19*451 ± 14*452 ± 20*303 ± 9
Lean body mass (g)264 ± 14373 ± 14*364 ± 14*372 ± 20*266 ± 8
Non-VF fat mass (g)21 ± 582 ± 10*65 ± 11*75 ± 10*32 ± 6
Total VF after study (g)5.8 ± 0.923.4 ± 4.3*21.3 ± 1.6*4.6 ± 0.76.1 ± 1.0
Epididymal (g)2.9 ± 0.39.2 ± 1.6*8.2 ± 0.7*0.1 ± 0.12.6 ± 0.5
Perinephric (g)1.4 ± 0.38.3 ± 0.7*8.1 ± 0.6*0.4 ± 0.41.9 ± 0.5
Mesenteric (g)1.5 ± 0.35.9 ± 0.4*4.8 ± 0.6*4.1 ± 0.4*1.4 ± 0.4
  • young (2-month-old), and old (20-month-old) F1 hybrids of F344 and Brown Norway rats were used in these experiments. The old rats underwent VF removal (VF), SC fat removal (SC), sham operation (SO), or CR (see research design and methods). The table depicts the amounts of VF or SC removed at the surgery, body weight, lean body mass, non-VF fat mass, total VF, and epididymal, perinephric, and mesenteric fat, which were determined at killing after the experiments.

  • *

    * P < 0.001 vs. young and CR;

  • P < 0.01 vs. young, CR, and SC. All data are presented as means ± SE.