TABLE 4

Metabolic characteristics of ZDF rats

BASAL
CLAMP
ZDVF+ZDVF−ZDVF+ZDVF−
n6666
Glucose (mmol/l)8.9 ± 0.48.5 ± 0.510.1 ± 0.7*8.4 ± 0.3
Insulin (pmol/l)76 ± 9*44 ± 2112 ± 10101 ± 5
FFA (mmol/l)1.99 ± 0.221.67 ± 0.132.53 ± 0.11*1.51 ± 0.16
GIR (mg · kg−1 · min−1)0002.1 ± 0.6
EGP (mg · kg−1 · min−1)13.8 ± 0.813.1 ± 1.613.3 ± 0.5*10.7 ± 0.6
Rd (mg · kg−1 · min−1)13.8 ± 0.813.1 ± 1.613.7 ± 0.814.2 ± 0.8
  • Plasma glucose, insulin, FFA levels, glucose infusion rate (GIR), EGP, and glucose uptake (Rd) at basal conditions and during the pancreatic clamps in ZDVF+ (no VF removed) and ZDVF (VF removed) rats.

  • *

    * P < 0.001 vs. ZDVF−,

  • P < 0.001 vs. basal. All data are presented as means ± SE.