TABLE 2

Mean serum insulin, liver weight, and heart weight at day 60 in placebo-treated controls, placebo-treated diabetic db/db mice, and VEGF antibody-treated diabetic db/db mice

Day 60
Serum insulin (μg/l)Liver weight (mg)Heart weight (mg)
Control, placebo2.86 ± 0.291,136 ± 36103 ± 4
Diabetic, placebo18.82 ± 1.60*2,272 ± 88*109 ± 3
Diabetic, VEGF antibody16.85 ± 1.67*1,891 ± 65103 ± 3
  • Data are means ± SE (n = 6–12 in each group).

  • *

    * P < 0.01 vs. nondiabetic controls;

  • P < 0.05 vs. the two other groups.