TABLE 4

Gene transcripts remain unaltered by 10 days of insulin treatment in type 2 diabetic patients

Fold ΔGene name
Structural/contractile genes
 ↑2.9*Calmodulin Type I
 ↓2.1*Troponin I fast-twitch
 ↓2.1Troponin C fast-twitch
 ↓2.0*Skeletal muscle C-protein
 ↓2.0Troponin I slow-twitch
 ↓1.9Tropomyosin
Stress response/energy metabolism
 ↑3.2Heat shock protein, 70 kDa
 ↓2.0NADH dehydrogenase-ubiquinone
Growth factor/tissue development
 ↑2.9IGFBP-5
 ↓2.2*MCL1
 ↓2.1*Cadherin FIB3
  • *

    * P < 0.0001,

  • P < 0.01,

  • P < 0.05, with P values calculated from t test on the average difference between control and D2+ subjects.