TABLE 2

Clinical and metabolic characteristics of obese subjects before and after a VLCD treatment

VLCD
PretreatmentPosttreatment
n66
Age (years)45 ± 345 ± 3
Body weight (kg)95.0 ± 6.386.7 ± 6.0*
BMI (kg/m2)34.5 ± 1.731.8 ± 2.2*
Skinfold thickness (mm)206 ± 15179 ± 13
HbA1c (%)5.5 ± 0.25.4 ± 0.1
Glucose (mmol/l)5.2 ± 0.15.0 ± 0.12
Insulin (pmol/l)96.0 ± 13.484 ± 7.8
Clamp insulin (pmol/l)6,931 ± 7265,998 ± 693
Triglyceride (mg/dl)183 ± 51115 ± 20
Free fatty acid (mmol/l)0.53 ± 0.080.52 ± 0.06
GDR (mg · kg−1 · min−1)8.2 ± 0.710.2 ± 1.3
  • Data are means ± SD. Glucose, insulin, free fatty acid, and triglycerides were measured after an overnight fast. Skinfold thickness = abdominal + subscapular + suprailiac + chest.

  • *

    * P < 0.01 vs. pretreatment;

  • P < 0.05 vs. pretreatment.