TABLE 1

Expansion of dendritic cell subsets in the spleen and their expression of maturation markers after one 10-day course of Flt3-ligand in vivo

Cell number (×10−6)Fold increaseI-A+ (%)CD80+ (%)CD86+ (%)
mDC
    No Flt3-ligand8.84 ± 0.881.9 ± 0.8164.8 ± 2.841.7 ± 1.3
    +Flt3-ligand114 ± 28.912.951.9 ± 1.0466.7 ± 4.751.5 ± 5.9
pDC
    No Flt3-ligand4.96 ± 1.3795.8 ± 0.9834.8 ± 6.352.2 ± 2.4
    +Flt3-ligand29.0 ± 5.275.891.0 ± 1.3952.9 ± 1.427.2 ± 0.8
  • Data are average ± SD.