TABLE 2

Comparison of baseline characteristics between NGT subjects who remained NGT or who developed IFG-IGT or type 2 diabetes during follow-up

NGTIFG-IGTType 2 diabetesP
n (M/F)1,190 (515/675)199 (100/99)40 (23/17)
Age (years)44 ± 1248 ± 1251 ± 12<0.0001
BMI (kg/m2)25.1 ± 3.626.4 ± 3.626.4 ± 4.8<0.0001
Waist-height index (cm/m2)29.4 ± 4.331.1 ± 4.531.2 ± 4.30.0038
WHR0.86 ± 0.090.89 ± 0.080.90 ± 0.070.044
Plasma glucose (mmol/l)
    Fasting5.42 (5.03–5.71)5.48 (5.20–5.71)5.54 (5.25–5.86)0.014
    2-h5.65 (4.86–6.33)5.99 (5.23–6.69)5.76 (4.63–6.70)0.0008
Serum insulin (mU/l)
    Fasting3.87 (2.96–5.42)4.49 (3.26–6.27)4.49 (2.45–8.35)0.0029
    2-h20.8 (13.0–32.1)25.3 (15.7–45.2)23.5 (9.6–56.9)0.0027
HOMAIR0.93 (0.69–1.31)1.08 (0.79–1.56)1.12 (0.60–2.07)0.0008
Insulinogenic index13.4 (7.9–24.6)12.9 (7.7–21.0)9.6 (5.9–17.0)0.26
Disposition index13.8 (8.1–24.8)11.0 (7.2–19.6)5.9 (4.4–14.2)0.0012
Systolic blood pressure (mmHg)124.7 ± 16.1130.4 ± 16.5132.7 ± 17.60.08
Diastolic blood pressure (mmHg)76.9 ± 10.180.9 ± 10.182.5 ± 10.30.0059
Total cholesterol (mmol/l)5.47 ± 1.105.55 ± 1.035.73 ± 1.300.38
LDL cholesterol (mmol/l)3.52 ± 1.073.56 ± 1.123.57 ± 1.400.081
HDL cholesterol (mmol/l)1.42 ± 0.331.35 ± 0.311.37 ± 0.370.24
Triglycerides (mmol/l)1.01 (0.8–1.4)1.11 (0.87–1.46)1.25 (0.98–1.81)0.27
FFA (mmol/l)641.0 (527.0–764.5)704.9 ± 182.0750.2 ± 220.40.045
Apolipoprotein B (mg/dl)88.5 ± 22.193.9 ± 21.590.5 ± 19.30.20
Physical activity, metabolic equivalents (s/day3)6.55 (4.46–8.75)5.75 (3.5–8.0)5.45 (2.49–8.99)0.044
Physical activity level1.23 (1.15–1.31)1.22 (1.12–1.28)1.20 (1.09–1.31)0.037
  • Data are the means ± SD or median (interquartile range). P values (ANCOVA) were adjusted for age, sex, and BMI.