TABLE 3

Comparison of baseline characteristics between IFG-IGT subjects who converted to NGT, remained IFG-IGT or developed type 2 diabetes during follow-up

NGTIFG-IGTType 2 diabetesP
n (M/F)379 (189/190)221 (97/124)86 (43/43)
Age (years)48 ± 1253 ± 1252 ± 11<0.0001
BMI (kg/m2)26.2 ± 4.127.4 ± 4.229.4 ± 4.2<0.0001
Waist-height index (cm/m2)31.1 ± 4.432.5 ± 4.134.5 ± 4.20.097
WHR0.89 ± 0.090.89 ± 0.090.92 ± 0.10.37
HbA1c (%)5.4 ± 0.55.7 ± 0.65.7 ± 0.40.0010
Plasma glucose (mmol/l)
    Fasting6.16 (5.76–6.38)6.16 (5.59–6.38)6.27 (5.76–6.61)0.22
    30-min9.28 ± 1.499.70 ± 1.4110.19 ± 1.50<0.0001
    2-h7.44 ± 1.348.03 ± 1.468.29 ± 1.64<0.0001
Serum insulin (mU/l)
    Fasting4.95 (3.63–7.49)5.52 (3.95–8.31)7.27 (4.85–10.93)0.054
    2-h32.2 (22.9–58.0)48.2 (26.8–72.1)60.6 (32.2–112.0)0.0003
HOMAIR1.34 (0.96–2.03)1.48 (1.03–2.24)1.83 (1.32–3.0)0.043
Insulinogenic index12.7 (7.2–20.0)9.8 (6.0–18.4)11.5 (8.1–23.5)0.009
Disposition index8.6 (5.6–14.8)6.9 (4.3–11.4)5.9 (3.5–11.1)0.0004
Systolic blood pressure (mmHg)130 (119–141)135.5 (123.1–147)140.0 (127–158)0.17
Diastolic blood pressure (mmHg)80.2 ± 11.681.9 ± 10.284.7 ± 10.50.62
Total cholesterol (mmol/l)5.8 ± 1.25.8 ± 1.15.8 ± 0.90.23
LDL cholesterol (mmol/l)3.78 ± 1.153.73 ± 1.133.76 ± 1.040.051
HDL cholesterol (mmol/l)1.34 ± 0.321.33 ± 0.321.24 ± 0.300.31
Triglycerides (mmol/l)1.2 (0.86–1.77)1.35 (1.0–1.84)1.61 (1.05–2.07)0.68
FFA (mmol/l)695.0 (547.3–875.5)755.4 ± 219.3768.2 ± 233.20.92
Apolipoprotein B (mg/dl)95.3 ± 23.296.7 ± 22.793.2 ± 24.50.60
Physical activity, metabolic equivalents (s/day3)5.8 (3.5–8.5)5.0 (2.7–7.7)4.8 (1.9–7.3)0.12
Physical activity level1.21 (1.12–1.30)1.19 (1.10–1.28)1.17 (1.08–1.26)0.18
  • Data are the means ± SD or median (interquartile range). P values (ANCOVA) were adjusted for age, sex, and BMI.