TABLE 5

The effects of combinations of risk factors for type 2 diabetes as estimated from Cox proportional hazards regression

HR (95% CI)
BMI2.9 (2.0–4.2)
FPG1.9 (1.3–2.8)
Combined family history of diabetes and BMI3.4 (2.3–5.1)
Combined family history of diabetes and WHR1.9 (1.3–2.8)
Combined family history of diabetes and FPG3.1 (2.1–4.6)
Combined FPG-BMI3.1 (2.1–4.8)
Combined family history of diabetes, BMI, and FPG3.7 (2.3–6.1)
  • All effects are statistically significant at the P < 0.0001 level. Hazard ratio (HR) (95% CI) is for comparison of those with all risk factors to the rest of the population. Family history of diabetes refers to first-degree relatives of type 2 diabetic patients. BMI refers to BMI dichotomized as ≥30 kg/m2. WHR is >0.90 in men and >0.85 in women. FPG is ≥5.6 mmol/l.