TABLE 2

Genotypic association with adiponectin in non-Hispanic whites and African Americans

SNPGenotypeWhites
African Americans
nAdiponectin*P valuenAdiponectin*P value
−12,823CC41510.4 ± 0.20.44368.7 ± 0.20.7
CT10910.6 ± 0.4359.1 ± 0.6
TT612.0 ± 1.60
−11,391GG51610.2 ± 0.20.0025278.8 ± 0.20.11
GA9411.9 ± 0.41510.6 ± 0.9
AA613.2 ± 1.60
−10,068GG30010.7 ± 0.20.032299.2 ± 0.30.15
GA25410.6 ± 0.32428.6 ± 0.3
AA729.1 ± 0.5748.5 ± 0.4
−4,521CC37110.6 ± 0.20.192539.1 ± 0.30.14
CT22310.2 ± 0.32378.7 ± 0.3
TT389.6 ± 0.6578.5 ± 0.5
−4,041AA23610.2 ± 0.30.8N/A
AC30710.4 ± 0.2
CC8411.0 ± 0.4
−657TT54610.3 ± 0.20.124868.9 ± 0.20.3
TG7910.9 ± 0.4608.5 ± 0.5
GG17.9 ± 3.927.4 ± 2.6
+45TT50510.4 ± 0.20.154868.9 ± 0.20.3
TG809.8 ± 0.4478.1 ± 0.5
GG910.0 ± 1.317.2 ± 3.6
+276GG33510.1 ± 0.20.052298.6 ± 0.30.03
GT23910.8 ± 0.32539.0 ± 0.3
TT4710.6 ± 0.6629.1 ± 0.5
+349AA49710.4 ± 0.20.55008.9 ± 0.20.3
AG12210.3 ± 0.4488.5 ± 0.5
GG99.9 ± 1.317.2 ± 3.6
+712GG23310.0 ± 0.30.171038.7 ± 0.40.6
GA31010.8 ± 0.22739.0 ± 0.2
AA8210.4 ± 0.41718.8 ± 0.3
+2,019AA23410.0 ± 0.30.171138.4 ± 0.40.5
A Del31010.8 ± 0.22649.0 ± 0.2
Del Del8410.4 ± 0.41688.7 ± 0.3
  • Data are least squares means ± SE from general linear models, modeling genotype as a categorical variable.

  • *

    * Adjusted for sex, puberty stage, BMI Z score, and waist Z score.

  • P values for additive trend in adiponectin by genotype from regression analysis.