TABLE 1

Body composition, energy balance, and plasma levels of substrates and hormones at the end of semistarvation and after 7 days of refeeding

SemistarvationControlRestricted
Body weight (g)222.2 ± 2.8222.5 ± 2.1
Body lipids (g)18.2 ± 1.38.7 ± 1.1*
Body proteins (g)45.7 ± 1.847.0 ± 1.2
Body water (g)145 ± 2.1155 ± 2.1
Insulin (ng/ml)1.89 ± 0.471.78 ± 0.95
Glucose (mg/dl)228 ± 12174 ± 15*
HOMA index24.8 ± 1.217.6 ± 0.9*
NEFA (mmol/l)0.107 ± 0.0120.061 ± 0.012*
RefeedingControlRefed
Weight gain (g)64 ± 468 ± 6
Fat gain (g)11.5 ± 0.718.0 ± 0.7*
Protein gain (g)11.2 ± 2.811.0 ± 1.2
Energy gain (kJ)686 ± 31945 ± 40*
ME intake (kJ)2,404 ± 512,288 ± 47
Energy expenditure (kJ)1,718 ± 861,343 ± 78*
Gross efficiency (%)0.29 ± 0.030.41 ± 0.03*
Net energy expenditure (kJ)1,244 ± 152781 ± 85*
Net energy expenditure/ ME intake (%)51.7 ± 2.934.1 ± 2.5*
Insulin (ng/ml)2.48 ± 0.232.55 ± 0.21
Glucose (mg/dl)178 ± 6202 ± 6*
HOMA index25.3 ± 1.329.6 ± 1.1*
NEFA (mmol/l)0.051 ± 0.0110.061 ± 0.012
  • Data are means ± SE of four different rats. HOMA index = (glucose [mg/dl] × insulin [mU/l])/405. ME, metabolizable energy.

  • *

    * P < 0.05 compared with controls.