TABLE 1

Characteristics of individuals in the genome-wide and population-based studies

nPercentage menAge (years)*BMI (kg/m2
Genome-wide association study
    Case-control study
        Diabetes3003819.2 ± 4.5 (5.5–24.9)38.9 ± 8.4
        No diabetes3344855.5 ± 9.8 (45.1–87.9)35.4 ± 8.0
    Siblings of case/control subjects
        Diabetes1403441.0 ± 8.3 (25.0–67.4)38.9 ± 9.3
        No diabetes1214727.8 ± 7.9 (12.3–42.1)36.9 ± 8.9
Population study
    Not in genome-wide study
        Diabetes1,2073839.7 ± 10.6 (10.7–78.0)38.3 ± 8.2
        No diabetes1,6274627.7 ± 11.6 (5.5–79.7)35.6 ± 8.2
    All
        Diabetes1,5613737.2 ± 12.1 (5.5–78.0)38.5 ± 8.4
        No diabetes1,9404631.1 ± 14.5 (5.5–85.3)35.7 ± 8.2
  • Data are means ± SD (range) or means ± SD unless otherwise indicated.

  • *

    * Age at last examination for nondiabetic individuals and age at onset of diabetes for diabetic individuals.

  • Maximum BMI observed after age 15 years in the longitudinal study.