TABLE 2

Linkage disequilibrium between SOD1 SNPs in DCCT/EDIC probands

Physical location
31,940,240
31,950,512
31,954,158
31,954,859
31,956,763
31,959,353
31,960,736
31,962,033
31,963,874
31,964,004
32,014,714
Location*
5′
5′
Intron 1
Intron 1
Intron 1
Intron 2
Intron 3
Intron 4
3′
3′ SFRS15
Intron 1 SFRS15
rs no.rs9974610rs202446rs17881180rs17884536rs17880998rs17878806rs17880753rs17880196rs17880135rs17881203rs204732
rs99746100.8350.9791.0001.0000.8330.8900.9700.9810.9300.835
rs2024460.5950.9711.0001.0000.7520.8770.9220.9740.9370.904
rs178811800.2460.3051.0001.0000.9061.0000.9360.9770.9180.962
rs178845360.0090.0070.0021.0000.9700.9801.0001.0001.0001.000
rs178809980.0250.0200.0060.3430.9810.9771.0001.0001.0000.955
rs178788060.1230.0800.0370.0450.1360.9370.9650.9170.9100.795
rs178807530.0070.0050.0020.9410.3220.0411.0001.0001.0000.870
rs178801960.0950.0680.0230.0190.0550.5260.0191.0001.0000.828
rs178801350.2650.3310.9120.0020.0070.0410.0020.0280.9490.974
rs178812030.0620.0830.2370.0010.0020.0110.0010.0080.2430.937
rs2047320.5950.7520.2860.0070.0200.0960.0050.0590.3070.077
  • Linkage disequilibrium between SOD1 and SFRS15 SNPs in white DCCT/EDIC probands. The values above and below the diagonal are D′ and r2, respectively. According to dbSNP build 125 (http://www.ncbi.nlm.nih.gov/SNP), the following are identical: rs17884536 = rs6650814; rs17880998 = rs4998557; rs17880196 = rs1041740; rs17880753 = rs2234694; rs17878806 = rs9967983. Physical location refers to build 36.2 of the human genome.

  • *

    * All SNPs are in SOD1 apart from those indicated, which are in SFRS15.