TABLE 2

In vitro inhibition of human adipocyte GLUT activity by dapagliflozin, phlorizin, phloretin, and cytochalasin B (20 μmol/l)

No BSA added
4% BSA added
% Inhibition, basal% Inhibition, + insulin% Inhibition, basal% Inhibition, + insulin
Dapagliflozin9 ± 1 (3)8 ± 3 (3)0 (1)0 (1)
Phlorizin10 (1)12 (1)11 (1)5 (1)
Phloretin78 (1)79 (1)77 (1)77 (1)
Cytochalasin B88 ± 2 (4)89 ± 0.3 (4)86 ± 1 (3)88 ± 1 (3)
  • Data in parentheses are n. BSA, bovine serum albumin.