TABLE 3

Plasma glucose, insulin, and corticosterone levels prior to and during the hyperinsulinemic-euglycemic clamp

ARC salineARC GLP-1i3vt GLP-1
Glucose (mmol/l)
    Basal4.9 ± 0.14.6 ± 0.14.9 ± 0.2
    ICV4.6 ± 0.14.4 ± 0.54.9 ± 0.3
    Clamp5.2 ± 0.25.4 ± 0.35.3 ± 0.2
Insulin (pmol/l)
    Basal67 ± 2169 ± 1666 ± 13
    ICV48 ± 1060 ± 1752 ± 11
    Clamp285 ± 59295 ± 48246 ± 37
Corticosterone (nmol/l)
    Basal13 ± 315 ± 313 ± 3
    ICV17 ± 315 ± 313 ± 2
    Clamp13 ± 318 ± 216 ± 2
  • Data are means ± SE. Neither insulin nor corticosterone levels significantly changed over time in any group during the hyperinsulinemic-euglycemic clamp. ICV, intracerebroventricular.