TABLE 2

AT characteristics of lean versus overweight/obese volunteers

LeanOverweight/obesePCorrelation with percent fat
rP
n68
Gene expression (AU)
    Leptin mRNA0.19 ± 0.110.57 ± 0.12<0.050.74<0.05
    PDK1 mRNA0.63 ± 0.240.45 ± 0.21<0.05−0.10
    VEGF mRNA2.46 ± 1.111.04 ± 0.34<0.05−0.78<0.05
    ANG1 mRNA0.41 ± 0.130.69 ± 0.11<0.050.73<0.05
    PPARγ1 mRNA1.33 ± 0.360.74 ± 0.21<0.05−0.73<0.05
    COL6 mRNA0.32 ± 0.170.53 ± 0.16<0.050.55<0.05
    CD68 antigen mRNA0.23 ± 0.050.62 ± 0.27<0.050.64<0.05
    MAC2/CD163 mRNA0.56 ± 0.221.49 ± 0.63<0.050.72<0.05
    MIP1α mRNA0.02 ± 0.010.21 ± 0.18<0.050.60<0.05
    MCP1 mRNA0.12 ± 0.050.25 ± 0.11<0.050.43
Cytokine release (pg/mg tissue × h)<0.05
    MIP1α0.44 ± 0.380.96 ± 0.69<0.050.60<0.05
    MCP12.26 ± 0.832.36 ± 1.18<0.050.12
    IL1α0.09 ± 0.080.20 ± 0.07<0.050.67<0.05
  • Data are means ± SD. MCP1, macrophage chemoattractant protein 1.