TABLE 1

Subjects analyzed in association studies

Samplen (M/F)*Sample typeAge (years)BMIPercent body fat
Full-heritage Pima Indian GWAS413 (239/174)Metabolically studied inpatients26.7 ± 6.234.0 ± 7.533.0 ± 8.5
Full-heritage Pima Indian population3,234 (1,350/1,884)Population36.9 ± 14.633.5 ± 7.9NA
Full-heritage Pima population nonoverlapping with GWAS2,843 (1,130/1,713)Population excluding GWAS38.1 ± 13.433.4 ± 7.8NA
Caucasians
    French adult case/control subjects695 (147/548)Case subjects44.1 ± 12.047.3 ± 7.6NA
731 (181/550)Control subjects55.2 ± 8.221.8 ± 1.9NA
    French children case/control subjects685 (310/375) 707 (332/375)Case subjects Control subjects10.9 ± 3.3 11.9 ± 2.329.5 ± 6.5 17.6 ± 2.3NA NA
    German school children case/control subjects283 (136/147) 715 (337/378)Case subjects Control subjects11.6 ± 3.6 11.7 ± 2.730.5 ± 6.2 18.1 ± 2.1NA NA
    Old Order Amish1,149 (592/557)Family-based49.6 ± 16.830.0 ± 4.7NA
Mixed-heritage Native American2,531 (1,120/1,411)Population29.1 ± 11.732.8 ± 8.6NA
  • Data are means ± SD. NA indicates information on percent body fat was not available.

  • *M, males; F, females.

  • †Age, BMI, and percent body fat at first visit.

  • ‡Age and BMI averaged over all visits.