TABLE 1

Phylogenetic analysis of the taxa enriched or depleted in prebiotic-fed mice using pyrosequencing

Abundance (percent of total sequences)
RankRDP classificationOb-CTOb-PreChange (%)*
SubclassActinobacteria; Actinobacteria; Actinobacteridae0.006 ± 0.0040.12 ± 0.051,971
OrderActinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales0 ± 00.12 ± 0.05Ob-Pre
FamilyActinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales; Bifidobacteriaceae0 ± 00.12 ± 0.05Ob-Pre
GenusActinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium0 ± 00.12 ± 0.05Ob-Pre
PhylumBacteroidetes52 ± 364 ± 224
ClassBacteroidetes; Bacteroidia52 ± 364 ± 223
OrderBacteroidetes; Bacteroidia; Bacteroidales52 ± 364 ± 223
FamilyBacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae2.6 ± 0.54.1 ± 0.555
GenusBacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae; Prevotella1.4 ± 0.22.4 ± 0.273
GenusBacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae; Tannerella1.4 ± 0.21.9 ± 0.133
GenusBacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae; Barnesiella8.5 ± 0.810.7 ± 0.626
PhylumFirmicutes44 ± 429 ± 2−33
ClassFirmicutes; Clostridia; Clostridia42 ± 428 ± 2−34
OrderFirmicutes; Clostridia; Clostridiales42 ± 427 ± 2−35
GenusFirmicutes; Clostridia; Clostridiales; Ruminococcaceae; Anaerofilum0.04 ± 0.010.003 ± 0.003−93
GenusFirmicutes; Clostridia; Clostridiales; Ruminococcaceae; Anaerotruncus1.0 ± 0.10.26 ± 0.04−74
GenusFirmicutes; Clostridia; Clostridiales; Ruminococcaceae; Subdoligranulum0.015 ± 0.0070.07 ± 0.02376
FamilyLachnospiraceae33 ± 318 ± 2−44
GenusFirmicutes; Clostridia; Clostridiales; Lachnospiraceae; Syntrophococcus0.012 ± 0.0050 ± 0Ob-CT
GenusFirmicutes; Clostridia; Clostridiales; Lachnospiraceae; Marvinbryantia2.1 ± 0.60.8 ± 0.2−63
GenusFirmicutes; Clostridia; Clostridiales; Lachnospiraceae; Anaerostipes0.023 ± 0.0080.003 ± 0.003−88
ClassProteobacteria; Betaproteobacteria0.18 ± 0.080.6 ± 0.1259
OrderProteobacteria; Betaproteobacteria; Burkholderiales0.17 ± 0.080.6 ± 0.1271
FamilyProteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae0.17 ± 0.080.6 ± 0.1269
GenusProteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Parasutterella0.17 ± 0.080.6 ± 0.1269
  • Data are mean ± SEM.

  • *P < 0.05, as determined by a two-tailed Student t test with equal variance. Ob-CT, found only in the control group; Ob-Pre, found only in prebiotic-fed mice.