Table 3

Heritability estimates with genetic and environmental correlations for T2D-related quantitative traits in BetaGene adjusting for age, sex, and BMI

Environmental correlations (ρE)Genetic correlations (ρG)
AIRgHOMABSIHOMAIRFasting glucoseFasting insulinDISG
AIRg0.56 ± 0.080.28 ± 0.11−0.24 ± 0.080.49 ± 0.100.07 ± 0.100.48 ± 0.100.85 ± 0.050.76 ± 0.12
HOMAB0.31 ± 0.100.55 ± 0.07−0.29 ± 0.080.70 ± 0.04−0.34 ± 0.090.81 ± 0.040.17 ± 0.10−0.05 ± 0.09
SI−0.72 ± 0.11−0.61 ± 0.110.33 ± 0.08−0.83 ± 0.09−0.23 ± 0.13−0.84 ± 0.09−0.24 ± 0.21−0.60 ± 0.25
HOMAIR−0.11 ± 0.110.78 ± 0.04−0.27 ± 0.070.48 ± 0.070.29 ± 0.100.99 ± 0.01−0.26 ± 0.09−0.10 ± 0.08
Fasting glucose−0.45 ± 0.09−0.35 ± 0.08−0.03 ± 0.080.35 ± 0.070.49 ± 0.060.25 ± 0.10−0.46 ± 0.07−0.10 ± 0.08
Fasting insulin−0.07 ± 0.110.76 ± 0.04−0.28 ± 0.080.99 ± 0.010.29 ± 0.080.50 ± 0.07−0.23 ± 0.09−0.11 ± 0.09
DI0.68 ± 0.05−0.13 ± 0.130.43 ± 0.07−0.01 ± 0.14−0.03 ± 0.12−0.02 ± 0.140.44 ± 0.090.62 ± 0.12
SG0.04 ± 0.100.10 ± 0.160.46 ± 0.070.02 ± 0.16−0.16 ± 0.140.03 ± 0.160.41 ± 0.070.28 ± 0.09
  • Heritability estimates with SEs are given on the diagonal in boldface type. Genetic and environmental correlations with SEs are provided above and below the diagonal, respectively.