Table 1

Clinical characteristics of the GUARDIAN cohorts

IRASIRASFSBetaGeneTRIPOD
Demographics
 Sample size1871,0341,214125
 Age (years)58.8 ± 8.340.6 ± 13.734.6 ± 7.934.8 ± 6.3
 Women (%)58.359.072.1100.0
 BMI (kg ⋅ m−2)28.9 ± 5.128.3 ± 5.729.5 ± 6.130.6 ± 5.4
Dynamic measures
 AIRg (µU ⋅ mL−1 ⋅ min)673 ± 702760 ± 649569 ± 480488 ± 450
SI (×10−4 ⋅ min−1 ⋅ µU−1 ⋅ mL)1.33 ± 1.242.14 ± 1.863.03 ± 1.632.57 ± 1.79
 DI1,245 ± 1,1841,202 ± 1,2361,409 ± 9461,004 ± 724
SG (min−1)0.0208 ± 0.00880.0202 ± 0.00910.0178 ± 0.00670.0157 ± 0.0041
Basal measures
 HOMAB128.7 ± 42.9120.8 ± 45.689.4 ± 45.3119.4 ± 40.3
 HOMAIR1.99 ± 1.031.67 ± 1.040.974 ± 0.7221.87 ± 0.98
 Fasting glucose (mg ⋅ dL−1)96.8 ± 10.193.4 ± 9.590.8 ± 11.598.3 ± 9.5
 Fasting insulin (mL ⋅ units ⋅ L−1)18.39 ± 11.6114.90 ± 11.048.69 ± 6.5116.57 ± 8.90
  • Data are means ± SD unless otherwise indicated.