Skip to main content
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care
  • Subscribe
  • Log in
  • My Cart
  • Follow ada on Twitter
  • RSS
  • Visit ada on Facebook
Diabetes

Advanced Search

Main menu

  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care

User menu

  • Subscribe
  • Log in
  • My Cart

Search

  • Advanced search
Diabetes
  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
Original Contribution

Oral Administration of D-Ribose in Diabetes Mellitus

  1. Terry Steinberg, M.D.,
  2. Russell L Poucher, M.D.,
  3. Raj K Sarin, M.D.,
  4. Richard B Rees, B.S. and
  5. Grant Gwinup, M.D.
  1. University of California Irvine, Orange, California 92668
Diabetes 1970 Jan; 19(1): 11-16. https://doi.org/10.2337/diab.19.1.11
PreviousNext
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

Thirty-four subjects were categorized on the basis of their glucose tolerance as normal (thirteen subjects), probable diabetics (six subjects), mild diabetics (five subjects), tolbutamide-responsive diabetics (five subjects) and insulin-dependent diabetics (five subjects). Fifteen grams of d-ribose dissolved in six ounces of water were administered orally to each of the subjects and the effect on serum glucose concentration was measured. The hypoglycemie effect of d-ribose varied in an orderly and progressive manner through the different categories of glucose intolerance. As their glucose intolerance increased in severity, the subjects were significantly less responsive to the blood glucose lowering effect of d-ribose.

The serum immunoreactive insulin concentration in response to the oral administration of d-ribose was measured in the normal and mild diabetic subjects. The mild diabetics had a mean peak increase in immunoreactive insulin which was 2.6-fold greater than the normal subjects; however, the insulin concentrations attained were not significant in either group. Thus the insulinogenic response as determined in peripheral venous blood does not account for the differential hypoglycemie effect of d-ribose.

Log in using your username and password

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.
PreviousNext
Back to top

In this Issue

January 1970, 19(1)
  • Table of Contents
  • Index by Author
Sign up to receive current issue alerts
View Selected Citations (0)
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about Diabetes.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Oral Administration of D-Ribose in Diabetes Mellitus
(Your Name) has forwarded a page to you from Diabetes
(Your Name) thought you would like to see this page from the Diabetes web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Oral Administration of D-Ribose in Diabetes Mellitus
Terry Steinberg, Russell L Poucher, Raj K Sarin, Richard B Rees, Grant Gwinup
Diabetes Jan 1970, 19 (1) 11-16; DOI: 10.2337/diab.19.1.11

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Add to Selected Citations
Share

Oral Administration of D-Ribose in Diabetes Mellitus
Terry Steinberg, Russell L Poucher, Raj K Sarin, Richard B Rees, Grant Gwinup
Diabetes Jan 1970, 19 (1) 11-16; DOI: 10.2337/diab.19.1.11
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Quantitative Assay for Human Cytoplasmic Islet Cell Antibodies
  • Effects of Fasting on Plasma Glucose and Prolonged Tracer Measurement of Hepatic Glucose Output in NIDDM
  • Calculated Pattern of Intraportal Insulin Appearance Without Independent Assessment of C-Peptide Kinetics
Show more Original Contribution

Similar Articles

Navigate

  • Current Issue
  • Online Ahead of Print
  • Scientific Sessions Abstracts
  • Collections
  • Archives
  • Submit
  • Subscribe
  • Email Alerts
  • RSS Feeds

More Information

  • About the Journal
  • Instructions for Authors
  • Journal Policies
  • Reprints and Permissions
  • Advertising
  • Privacy Policy: ADA Journals
  • Copyright Notice/Public Access Policy
  • Contact Us

Other ADA Resources

  • Diabetes Care
  • Clinical Diabetes
  • Diabetes Spectrum
  • Scientific Sessions Abstracts
  • Standards of Medical Care in Diabetes
  • BMJ Open - Diabetes Research & Care
  • Professional Books
  • Diabetes Forecast

 

  • DiabetesJournals.org
  • Diabetes Core Update
  • ADA's DiabetesPro
  • ADA Member Directory
  • Diabetes.org

© 2021 by the American Diabetes Association. Diabetes Print ISSN: 0012-1797, Online ISSN: 1939-327X.