Monoamine Oxidase Activity in Diabetes

Ellen Billett; Simon Hanley; Stanley Heptinstall; R John Mayer

doi:10.2337/diab.32.2.130

Original Contributions

Monoamine Oxidase Activity in Diabetes

Ellen Billett,
Simon Hanley,
Stanley Heptinstall and
R John Mayer

Departments of Biochemistry, University of Nottingham Medical School, Queen's Medical Centre Nottingham NG7 2UH, United Kingdom
Medicine, University of Nottingham Medical School, Queen's Medical Centre Nottingham NG7 2UH, United Kingdom

Address reprint requests to Dr. Ellen Billett at the above address.

Diabetes 1983 Feb; 32(2): 130-133. https://doi.org/10.2337/diab.32.2.130

Abstract

Monoamine oxidase (MAO) activities were measured in platelets from insulin-dependent and non-insulin-dependent diabetic subjects and in platelets from nondiabetic controls. Circulating levels of glycosylated hemoglobin (HbA₁) were determined simultaneously. Mean MAO activities were not significantly different in any of these groups. MAO activity did not relate to the age of the individual, but mean values for females were higher than mean values for males in healthy controls and in insulin-dependent diabetics. In this study mean HbA₁ levels were higher in female than in male diabetics. There was no relationship between MAO activity and HbA₁, level when results for males and females were analyzed separately.