Circulating Immune Complexes and Platelet Thromboxane Synthesis in Patients with Insulin-dependent (Type I) Diabetes Mellitus
Abstract
Platelets from diabetic subjects with circulating immune complexes (CIC) synthesized greater amounts of thromboxane than did platelets from CIC-negative patients or controls. In view of the known action of CIC on platelet function, a relationship between these two factors may be suggested in the initiation and progression of microangiopathy in diabetes.
- Received February 18, 1983.
- Revision received January 4, 1984.
- Accepted January 4, 1984.
- Copyright © 1984 by the American Diabetes Association
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