Prevention of Diabetic Vascular Dysfunction by Guanidines: Inhibition of Nitric Oxide Synthase Versus Advanced Glycation End-Product Formation

Ronald G Tilton; Katherine Chang; Khalid S Hasan; Samuel R Smith; J Mark Petrash; Thomas P Misko; William M Moore; Mark G Currie; John A Corbett; Michael L McDaniel; Joseph R Williamson

doi:10.2337/diab.42.2.221

Original Articles

Prevention of Diabetic Vascular Dysfunction by Guanidines: Inhibition of Nitric Oxide Synthase Versus Advanced Glycation End-Product Formation

Ronald G Tilton,
Katherine Chang,
Khalid S Hasan,
Samuel R Smith,
J Mark Petrash,
Thomas P Misko,
William M Moore,
Mark G Currie,
John A Corbett,
Michael L McDaniel and
Joseph R Williamson

Departments of Ophthalmology, Pathology, and Pediatrics, Washington University School of Medicine, and the Department of Molecular Pharmacology, Monsanto Corporate Research St. Louis, Missouri

Address correspondence and reprint requests to Dr. Ronald G. Tilton, Department of Pathology—Box 8118, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110.

Diabetes 1993 Feb; 42(2): 221-232. https://doi.org/10.2337/diab.42.2.221

Article Information

vol. 42 no. 2 221-232

DOI

https://doi.org/10.2337/diab.42.2.221

PubMed

7678825

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Received May 15, 1992
Revision received October 21, 1992
Accepted October 21, 1992
Published in print February 1, 1993.

Author Information

Ronald G Tilton,
Katherine Chang,
Khalid S Hasan,
Samuel R Smith,
J Mark Petrash,
Thomas P Misko,
William M Moore,
Mark G Currie,
John A Corbett,
Michael L McDaniel and
Joseph R Williamson

Departments of Ophthalmology, Pathology, and Pediatrics, Washington University School of Medicine, and the Department of Molecular Pharmacology, Monsanto Corporate Research St. Louis, Missouri

Address correspondence and reprint requests to Dr. Ronald G. Tilton, Department of Pathology—Box 8118, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110.

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