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Letter to the Editor

The Insulin Gene Promoter: A Simplified Nomenclature

  1. Michael German,
  2. Stephen Ashcroft,
  3. Kevin Docherty,
  4. Helena Edlund,
  5. Thomas Edlund,
  6. Steven Goodison,
  7. Hiroo Imura,
  8. Giulia Kennedy,
  9. Ole Madsen,
  10. Danielle Melloul,
  11. Larry Moss,
  12. Karl Olson,
  13. M Alan Permutt,
  14. Jacques Philippe,
  15. R Paul Robertson,
  16. William J Rutter,
  17. Palle Serup,
  18. Roland Stein,
  19. Donald Steiner,
  20. Ming-Jer Tsai and
  21. Michael D Walker
  1. University of California San Francisco, CA
  2. John Radcliffe Hospital Oxford, U.K.
  3. University of Aberdeen Aberdeen, Scotland
  4. University of Umea Umea, Sweden
  5. Kyoto University Kyoto, Japan
  6. Millenium Pharmaceuticals Cambridge, MA
  7. Hagedorn Research Institute Copenhagen, Denmark
  8. Hebrew University Jerusalem, Israel
  9. Tufts Medical School Boston, MA
  10. University of Minnesota Minneapolis, MN
  11. Washington University St. Louis, MO
  12. University of Geneva Geneva, Switzerland
  13. Vanderbilt University School of Medicine Nashville, TN
  14. University of Chicago Chicago, IL
  15. Baylor College of Medicine Houston, TX
  16. Weizmann Institute of Science Rehovot, Israel
  1. Address correspondence and reprint requests to Dr. Michael German, Hormone Research Institute, University of California at San Francisco, HSW 1090, Box 0534, 513 Parnassus Avenue, San Francisco, CA 94143-0534. german{at}cgl.ucsf.edu.
Diabetes 1995 Aug; 44(8): 1002-1004. https://doi.org/10.2337/diab.44.8.1002
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Abstract

The tools of molecular biology have rapidly expanded our knowledge of how β-cells regulate insulin gene expression. As this work has progressed in parallel in different laboratories, alternate nomenclature systems have been developed to describe the functionally important elements of the insulin gene. This jumble of names is confusing to those outside the field and intimidating to neophytes. Therefore, we have agreed to a simple, uniform set of names for the major insulin gene promoter elements.

  • Received February 1, 1995.
  • Revision received March 23, 1995.
  • Accepted March 23, 1995.
  • Copyright © 1995 by the American Diabetes Association

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August 1995, 44(8)
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The Insulin Gene Promoter: A Simplified Nomenclature
Michael German, Stephen Ashcroft, Kevin Docherty, Helena Edlund, Thomas Edlund, Steven Goodison, Hiroo Imura, Giulia Kennedy, Ole Madsen, Danielle Melloul, Larry Moss, Karl Olson, M Alan Permutt, Jacques Philippe, R Paul Robertson, William J Rutter, Palle Serup, Roland Stein, Donald Steiner, Ming-Jer Tsai, Michael D Walker
Diabetes Aug 1995, 44 (8) 1002-1004; DOI: 10.2337/diab.44.8.1002

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The Insulin Gene Promoter: A Simplified Nomenclature
Michael German, Stephen Ashcroft, Kevin Docherty, Helena Edlund, Thomas Edlund, Steven Goodison, Hiroo Imura, Giulia Kennedy, Ole Madsen, Danielle Melloul, Larry Moss, Karl Olson, M Alan Permutt, Jacques Philippe, R Paul Robertson, William J Rutter, Palle Serup, Roland Stein, Donald Steiner, Ming-Jer Tsai, Michael D Walker
Diabetes Aug 1995, 44 (8) 1002-1004; DOI: 10.2337/diab.44.8.1002
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