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Original Articles

Neutralization of TGF-β by Anti-TGF-β Antibody Attenuates Kidney Hypertrophy and the Enhanced Extracellular Matrix Gene Expression in STZ-Induced Diabetic Mice

  1. Kumar Sharma,
  2. Yulin Jin,
  3. Jia Guo and
  4. Fuad N Ziyadeh
  1. Renal-Electrolyte and Hypertension Division and Penn Center for Molecular Studies of Kidney Diseases, Department of Medicine, University of Pennsylvania School of Medicine Philadelphia, Pennsylvania
  2. Division of Nephrology, Department of Medicine, Thomas Jefferson University Philadelphia, Pennsylvania
  1. Address correspondence and reprint requests to Dr. Fuad N. Ziyadeh, Renal-Electrolyte & Hypertension Division, 700 Clinical Research Building, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104-6144.
Diabetes 1996 Apr; 45(4): 522-530. https://doi.org/10.2337/diab.45.4.522
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Article Information

vol. 45 no. 4 522-530
DOI 
https://doi.org/10.2337/diab.45.4.522
PubMed 
8603776

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received August 11, 1995
  • Revision received November 29, 1995
  • Accepted November 29, 1995
  • Published in print April 1, 1996.

Copyright & Usage 
Copyright © 1996 by the American Diabetes Association

Author Information

  1. Kumar Sharma,
  2. Yulin Jin,
  3. Jia Guo and
  4. Fuad N Ziyadeh
  1. Renal-Electrolyte and Hypertension Division and Penn Center for Molecular Studies of Kidney Diseases, Department of Medicine, University of Pennsylvania School of Medicine Philadelphia, Pennsylvania
  2. Division of Nephrology, Department of Medicine, Thomas Jefferson University Philadelphia, Pennsylvania
  1. Address correspondence and reprint requests to Dr. Fuad N. Ziyadeh, Renal-Electrolyte & Hypertension Division, 700 Clinical Research Building, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104-6144.

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Neutralization of TGF-β by Anti-TGF-β Antibody Attenuates Kidney Hypertrophy and the Enhanced Extracellular Matrix Gene Expression in STZ-Induced Diabetic Mice
Kumar Sharma, Yulin Jin, Jia Guo, Fuad N Ziyadeh
Diabetes Apr 1996, 45 (4) 522-530; DOI: 10.2337/diab.45.4.522

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Neutralization of TGF-β by Anti-TGF-β Antibody Attenuates Kidney Hypertrophy and the Enhanced Extracellular Matrix Gene Expression in STZ-Induced Diabetic Mice
Kumar Sharma, Yulin Jin, Jia Guo, Fuad N Ziyadeh
Diabetes Apr 1996, 45 (4) 522-530; DOI: 10.2337/diab.45.4.522
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