Targeted Disruption of the Tumor Necrosis Factor-α Gene: Metabolic Consequences in Obese and Nonobese Mice

John Ventre; Thomas Doebber; Margaret Wu; Karen MacNaul; Karla Stevens; Manolis Pasparakis; George Kollias; David E Moller

doi:10.2337/diab.46.9.1526

Rapid Publications

Targeted Disruption of the Tumor Necrosis Factor-α Gene: Metabolic Consequences in Obese and Nonobese Mice

John Ventre,
Thomas Doebber,
Margaret Wu,
Karen MacNaul,
Karla Stevens,
Manolis Pasparakis,
George Kollias and
David E Moller

Departments of Molecular Endocrinology, Merck Research Laboratories Rahway, New Jersey
Laboratory Animal Resources, Merck Research Laboratories Rahway, New Jersey
Hellenic Pasteur Institute Athens, Greece

Address correspondence and reprint requests to Dr. Thomas Doebber, Merck Research Laboratories, P.O. Box 2000, Rahway, NJ 07065.

Diabetes 1997 Sep; 46(9): 1526-1531. https://doi.org/10.2337/diab.46.9.1526

Article Information

vol. 46 no. 9 1526-1531

DOI

https://doi.org/10.2337/diab.46.9.1526

PubMed

9287059

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Received March 20, 1997
Revision received June 30, 1997
Accepted June 30, 1997
Published in print September 1, 1997.

Author Information

John Ventre,
Thomas Doebber,
Margaret Wu,
Karen MacNaul,
Karla Stevens,
Manolis Pasparakis,
George Kollias and
David E Moller

Departments of Molecular Endocrinology, Merck Research Laboratories Rahway, New Jersey
Laboratory Animal Resources, Merck Research Laboratories Rahway, New Jersey
Hellenic Pasteur Institute Athens, Greece

Address correspondence and reprint requests to Dr. Thomas Doebber, Merck Research Laboratories, P.O. Box 2000, Rahway, NJ 07065.

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