Insulin-Stimulated Akt Kinase Activity Is Reduced in Skeletal Muscle From NIDDM Subjects

Anna Krook; Richard A Roth; Xin Jian Jiang; Juleen R Zierath; Harriet Wallberg-Henriksson

doi:10.2337/diab.47.8.1281

Original Articles

Insulin-Stimulated Akt Kinase Activity Is Reduced in Skeletal Muscle From NIDDM Subjects

Anna Krook,
Richard A Roth,
Xin Jian Jiang,
Juleen R Zierath and
Harriet Wallberg-Henriksson

Department of Clinical Physiology, Karolinska Hospital Stockholm, Sweden
Department of Molecular Pharmacology, Stanford University School of Medicine Stanford, California

Address correspondence and reprint requests to Anna Krook, PhD, Department of Clinical Physiology, Karolinska Hospital, SE 171 76, Stockholm, Sweden. E-mail: ankr{at}klinfys.ks.se

Diabetes 1998 Aug; 47(8): 1281-1286. https://doi.org/10.2337/diab.47.8.1281

Article Information

vol. 47 no. 8 1281-1286

DOI

https://doi.org/10.2337/diab.47.8.1281

PubMed

9703329

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Received January 20, 1998
Revision received April 8, 1998
Accepted April 8, 1998
Published in print August 1, 1998.

Author Information

Anna Krook,
Richard A Roth,
Xin Jian Jiang,
Juleen R Zierath and
Harriet Wallberg-Henriksson

Department of Clinical Physiology, Karolinska Hospital Stockholm, Sweden
Department of Molecular Pharmacology, Stanford University School of Medicine Stanford, California

Address correspondence and reprint requests to Anna Krook, PhD, Department of Clinical Physiology, Karolinska Hospital, SE 171 76, Stockholm, Sweden. E-mail: ankr{at}klinfys.ks.se

Statistics from Altmetric.com

Article usage

Article usage: May 2001 to March 2021

Rendering graph...

	Abstract	Full	Pdf
May 2001	0	0	11
Jun 2001	6	0	13
Jul 2001	0	0	17
Aug 2001	1	0	13
Sep 2001	2	0	14
Oct 2001	2	0	19
Nov 2001	0	0	11
Dec 2001	0	0	10
Jan 2002	1	0	12
Feb 2002	0	0	9
Mar 2002	2	0	7
Apr 2002	1	0	1
May 2002	0	0	2
Jun 2002	1	0	7
Jul 2002	1	0	16
Aug 2002	0	0	5
Sep 2002	1	0	6
Oct 2002	2	0	14
Nov 2002	0	0	15
Dec 2002	2	0	7
Jan 2003	1	0	12
Feb 2003	1	0	12
Mar 2003	8	0	19
Apr 2003	3	0	14
May 2003	5	0	18
Jun 2003	4	0	25
Jul 2003	8	0	9
Aug 2003	7	0	10
Sep 2003	3	0	20
Oct 2003	9	0	18
Nov 2003	16	0	6
Dec 2003	8	0	12
Jan 2004	7	0	16
Feb 2004	8	0	17
Mar 2004	11	0	29
Apr 2004	12	0	19
May 2004	14	0	13
Jun 2004	10	0	15
Jul 2004	8	0	20
Aug 2004	17	0	6
Sep 2004	15	0	10
Oct 2004	15	0	10
Nov 2004	17	0	28
Dec 2004	15	0	13
Jan 2005	18	0	5
Feb 2005	12	1	5
Mar 2005	12	0	14
Apr 2005	14	0	18
May 2005	2	0	17
Jun 2005	4	0	6
Jul 2005	1	0	9
Aug 2005	2	0	15
Sep 2005	4	0	16
Oct 2005	6	0	9
Nov 2005	7	0	19
Dec 2005	6	0	12
Jan 2006	8	0	15
Feb 2006	5	0	10
Mar 2006	2	0	12
Apr 2006	7	0	12
May 2006	7	0	16
Jun 2006	5	0	8
Jul 2006	7	0	11
Aug 2006	6	0	9
Sep 2006	15	0	10
Oct 2006	5	0	7
Nov 2006	3	0	9
Dec 2006	19	0	18
Jan 2007	4	0	11
Feb 2007	4	0	16
Mar 2007	11	0	16
Apr 2007	6	0	12
May 2007	10	0	14
Jun 2007	11	0	23
Jul 2007	9	0	16
Aug 2007	6	0	14
Sep 2007	7	0	24
Oct 2007	12	0	17
Nov 2007	8	0	20
Dec 2007	5	0	14
Jan 2008	6	0	17
Feb 2008	3	0	16
Mar 2008	1	0	9
Apr 2008	7	0	15
May 2008	5	0	16
Jun 2008	9	0	8
Jul 2008	9	0	14
Aug 2008	10	0	10
Sep 2008	9	0	19
Oct 2008	21	0	30
Nov 2008	3	0	18
Dec 2008	7	0	15
Jan 2009	14	0	25
Feb 2009	9	0	15
Mar 2009	12	0	22
Apr 2009	9	0	25
May 2009	5	0	9
Jun 2009	7	0	15
Jul 2009	13	0	24
Aug 2009	13	0	13
Sep 2009	27	0	22
Oct 2009	13	0	24
Nov 2009	10	0	17
Dec 2009	12	0	12
Jan 2010	13	0	22
Feb 2010	4	0	13
Mar 2010	14	0	13
Apr 2010	14	0	18
May 2010	21	0	25
Jun 2010	2	0	13
Jul 2010	5	0	13
Aug 2010	11	0	17
Sep 2010	12	0	20
Oct 2010	8	0	28
Nov 2010	21	0	31
Dec 2010	6	0	30
Jan 2011	14	0	34
Feb 2011	10	0	29
Mar 2011	12	0	29
Apr 2011	12	0	28
May 2011	13	1	21
Jun 2011	6	1	21
Jul 2011	19	2	25
Aug 2011	10	0	21
Sep 2011	15	3	26
Oct 2011	16	2	24
Nov 2011	11	0	20
Dec 2011	22	2	16
Jan 2012	11	4	20
Feb 2012	10	1	13
May 2012	7	0	7
Jun 2012	12	2	6
Jul 2012	15	0	11
Aug 2012	21	0	8
Sep 2012	15	0	8
Oct 2012	11	1	6
Nov 2012	11	1	17
Dec 2012	8	0	7
Jan 2013	27	0	12
Feb 2013	14	0	6
Mar 2013	11	1	11
Apr 2013	33	0	15
May 2013	25	0	29
Jun 2013	7	0	15
Jul 2013	10	0	6
Aug 2013	11	0	9
Sep 2013	7	1	13
Oct 2013	9	0	9
Nov 2013	10	0	9
Dec 2013	11	1	13
Jan 2014	12	1	29
Feb 2014	9	0	9
Mar 2014	17	0	15
Apr 2014	19	0	17
May 2014	14	0	12
Jun 2014	17	1	9
Jul 2014	37	0	4
Aug 2014	9	0	3
Sep 2014	6	0	0
Oct 2014	11	0	2
Nov 2014	5	0	6
Dec 2014	21	0	2
Jan 2015	13	0	8
Feb 2015	13	0	4
Mar 2015	19	0	5
Apr 2015	16	0	3
May 2015	20	0	3
Jun 2015	21	1	3
Jul 2015	12	0	9
Aug 2015	13	0	5
Sep 2015	16	0	4
Oct 2015	12	0	5
Nov 2015	16	0	4
Dec 2015	30	0	10
Jan 2016	29	0	4
Feb 2016	24	0	2
Mar 2016	32	0	3
Apr 2016	13	0	2
May 2016	60	0	1
Jun 2016	50	0	2
Jul 2016	25	0	2
Aug 2016	33	0	2
Sep 2016	27	0	3
Oct 2016	38	0	2
Nov 2016	25	0	5
Dec 2016	44	0	5
Jan 2017	27	0	3
Feb 2017	34	0	5
Mar 2017	50	0	10
Apr 2017	24	0	2
May 2017	26	0	2
Jun 2017	18	0	1
Jul 2017	29	0	5
Aug 2017	27	0	5
Sep 2017	30	0	4
Oct 2017	42	0	8
Nov 2017	35	0	4
Dec 2017	35	0	7
Jan 2018	32	0	7
Feb 2018	15	0	1
Mar 2018	29	0	9
Apr 2018	46	0	7
May 2018	29	0	5
Jun 2018	19	0	4
Jul 2018	14	0	2
Aug 2018	30	0	5
Sep 2018	32	0	2
Oct 2018	34	0	4
Nov 2018	28	0	3
Dec 2018	24	0	4
Jan 2019	11	0	1
Feb 2019	34	0	8
Mar 2019	19	0	3
Apr 2019	35	0	4
May 2019	42	0	5
Jun 2019	27	0	3
Jul 2019	22	0	5
Aug 2019	16	0	7
Sep 2019	31	0	5
Oct 2019	47	0	5
Nov 2019	21	0	5
Dec 2019	22	0	5
Jan 2020	14	0	3
Feb 2020	27	0	4
Mar 2020	29	0	9
Apr 2020	27	0	3
May 2020	34	0	9
Jun 2020	12	0	1
Jul 2020	13	0	3
Aug 2020	6	0	1
Sep 2020	27	0	4
Oct 2020	21	0	2
Nov 2020	37	0	4
Dec 2020	40	0	6
Jan 2021	21	0	0
Feb 2021	20	0	1
Mar 2021	2	0	0