Insulin Activates ATP-Sensitive K+ Channels in Pancreatic β-Cells Through a Phosphatidylinositol 3-Kinase–Dependent Pathway

Farrukh A. Khan; Paulette B. Goforth; Min Zhang; Leslie S. Satin

doi:10.2337/diabetes.50.10.2192

Rapid Publications

Insulin Activates ATP-Sensitive K⁺ Channels in Pancreatic β-Cells Through a Phosphatidylinositol 3-Kinase–Dependent Pathway

Farrukh A. Khan,
Paulette B. Goforth,
Min Zhang and
Leslie S. Satin

Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond; the Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond; and the Division of Endocrinology and Metabolism, Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia

Diabetes 2001 Oct; 50(10): 2192-2198. https://doi.org/10.2337/diabetes.50.10.2192

Article Information

vol. 50 no. 10 2192-2198

DOI

https://doi.org/10.2337/diabetes.50.10.2192

PubMed

11574397

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Published in print October 1, 2001.

Author Information

Farrukh A. Khan,
Paulette B. Goforth,
Min Zhang and
Leslie S. Satin

Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond; the Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond; and the Division of Endocrinology and Metabolism, Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: September 2001 to March 2021

Rendering graph...

	Abstract	Full	Pdf
Sep 2001	50	62	69
Oct 2001	94	219	240
Nov 2001	12	106	88
Dec 2001	8	58	37
Jan 2002	7	50	56
Feb 2002	2	36	26
Mar 2002	4	31	29
Apr 2002	1	25	27
May 2002	5	17	14
Jun 2002	3	22	30
Jul 2002	0	17	15
Aug 2002	2	26	28
Sep 2002	2	27	23
Oct 2002	4	22	25
Nov 2002	6	29	42
Dec 2002	3	24	22
Jan 2003	2	20	23
Feb 2003	0	14	14
Mar 2003	3	24	25
Apr 2003	7	25	18
May 2003	9	25	19
Jun 2003	9	31	19
Jul 2003	5	21	26
Aug 2003	12	23	8
Sep 2003	12	41	20
Oct 2003	10	44	11
Nov 2003	12	29	12
Dec 2003	9	40	24
Jan 2004	8	49	30
Feb 2004	14	44	30
Mar 2004	10	58	32
Apr 2004	13	46	37
May 2004	18	56	24
Jun 2004	14	32	16
Jul 2004	22	39	21
Aug 2004	39	66	20
Sep 2004	22	49	17
Oct 2004	22	57	23
Nov 2004	17	35	17
Dec 2004	22	52	15
Jan 2005	17	56	9
Feb 2005	11	35	17
Mar 2005	17	79	22
Apr 2005	10	28	21
May 2005	23	49	28
Jun 2005	10	32	10
Jul 2005	4	29	15
Aug 2005	14	39	17
Sep 2005	10	33	24
Oct 2005	12	20	17
Nov 2005	8	29	14
Dec 2005	5	16	12
Jan 2006	7	28	7
Feb 2006	10	48	19
Mar 2006	8	36	14
Apr 2006	11	28	12
May 2006	5	21	12
Jun 2006	3	16	1
Jul 2006	3	28	20
Aug 2006	1	29	18
Sep 2006	6	31	12
Oct 2006	5	21	17
Nov 2006	9	31	9
Dec 2006	3	23	8
Jan 2007	6	21	15
Feb 2007	9	38	14
Mar 2007	6	20	5
Apr 2007	11	16	7
May 2007	3	29	17
Jun 2007	3	16	10
Jul 2007	4	19	6
Aug 2007	7	18	10
Sep 2007	2	11	8
Oct 2007	4	14	3
Nov 2007	14	22	10
Dec 2007	4	23	8
Jan 2008	13	38	23
Feb 2008	11	16	5
Mar 2008	25	22	11
Apr 2008	10	18	9
May 2008	13	12	8
Jun 2008	8	20	17
Jul 2008	17	17	10
Aug 2008	30	21	8
Sep 2008	19	9	9
Oct 2008	13	20	14
Nov 2008	10	15	14
Dec 2008	6	12	8
Jan 2009	6	18	4
Feb 2009	10	32	8
Mar 2009	15	37	13
Apr 2009	11	32	17
May 2009	1	12	8
Jun 2009	13	8	1
Jul 2009	17	47	4
Aug 2009	14	15	11
Sep 2009	12	12	4
Oct 2009	17	12	5
Nov 2009	16	7	6
Dec 2009	7	12	2
Jan 2010	13	7	6
Feb 2010	9	11	8
Mar 2010	18	13	11
Apr 2010	3	15	7
May 2010	12	10	7
Jun 2010	7	13	7
Jul 2010	11	11	10
Aug 2010	7	6	2
Sep 2010	8	10	11
Oct 2010	14	18	16
Nov 2010	9	28	13
Dec 2010	8	12	10
Jan 2011	15	17	14
Feb 2011	10	12	10
Mar 2011	16	14	14
Apr 2011	15	8	11
May 2011	7	16	9
Jun 2011	8	6	6
Jul 2011	10	5	14
Aug 2011	15	8	14
Sep 2011	14	3	3
Oct 2011	27	10	11
Nov 2011	17	13	18
Dec 2011	12	11	9
Jan 2012	28	12	7
Feb 2012	21	14	10
Mar 2012	25	10	9
Apr 2012	31	20	9
May 2012	34	16	15
Jun 2012	24	18	15
Jul 2012	20	14	13
Aug 2012	30	15	14
Sep 2012	18	13	14
Oct 2012	23	14	14
Nov 2012	45	23	16
Dec 2012	25	19	10
Jan 2013	33	38	23
Feb 2013	53	35	15
Mar 2013	42	20	13
Apr 2013	61	33	19
May 2013	48	28	26
Jun 2013	24	3	5
Jul 2013	32	8	6
Aug 2013	10	11	6
Sep 2013	15	9	7
Oct 2013	31	21	10
Nov 2013	25	20	12
Dec 2013	18	22	7
Jan 2014	41	26	11
Feb 2014	32	21	6
Mar 2014	56	36	7
Apr 2014	69	59	7
May 2014	59	49	11
Jun 2014	30	23	6
Jul 2014	68	19	8
Aug 2014	23	10	9
Sep 2014	24	12	3
Oct 2014	32	4	0
Nov 2014	27	12	11
Dec 2014	27	11	9
Jan 2015	29	16	1
Feb 2015	22	8	1
Mar 2015	42	25	9
Apr 2015	40	19	5
May 2015	36	13	5
Jun 2015	11	11	6
Jul 2015	15	8	5
Aug 2015	14	17	3
Sep 2015	19	8	2
Oct 2015	38	19	7
Nov 2015	34	12	5
Dec 2015	45	13	5
Jan 2016	41	14	8
Feb 2016	68	9	2
Mar 2016	62	20	25
Apr 2016	64	17	14
May 2016	36	25	13
Jun 2016	4	37	17
Jul 2016	4	20	10
Aug 2016	10	25	2
Sep 2016	7	24	5
Oct 2016	2	24	5
Nov 2016	2	21	43
Dec 2016	13	34	19
Jan 2017	3	29	7
Feb 2017	3	34	3
Mar 2017	2	31	1
Apr 2017	2	23	8
May 2017	5	27	12
Jun 2017	3	28	5
Jul 2017	3	16	10
Aug 2017	7	16	3
Sep 2017	1	15	3
Oct 2017	6	29	12
Nov 2017	2	38	2
Dec 2017	5	27	0
Jan 2018	2	20	5
Feb 2018	2	24	1
Mar 2018	3	20	7
Apr 2018	6	40	13
May 2018	2	47	4
Jun 2018	2	48	11
Jul 2018	1	28	2
Aug 2018	3	21	9
Sep 2018	2	51	8
Oct 2018	2	43	7
Nov 2018	4	32	7
Dec 2018	2	23	5
Jan 2019	2	23	4
Feb 2019	2	20	24
Mar 2019	2	24	8
Apr 2019	2	51	8
May 2019	2	47	8
Jun 2019	2	49	10
Jul 2019	2	38	6
Aug 2019	5	89	3
Sep 2019	7	253	4
Oct 2019	5	35	9
Nov 2019	2	34	6
Dec 2019	4	49	6
Jan 2020	6	17	12
Feb 2020	3	37	39
Mar 2020	0	18	6
Apr 2020	0	21	3
May 2020	0	34	6
Jun 2020	1	20	7
Jul 2020	4	39	20
Aug 2020	2	27	18
Sep 2020	5	28	3
Oct 2020	2	54	27
Nov 2020	2	54	13
Dec 2020	5	44	8
Jan 2021	0	27	17
Feb 2021	1	18	3
Mar 2021	0	3	1