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Table of Contents

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April 01 2001; volume 50 issue 4

Rapid Publication

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    Circulating Ghrelin Levels Are Decreased in Human Obesity
    Matthias Tschöp, Christian Weyer, P. Antonio Tataranni, Viswanath Devanarayan, Eric Ravussin and Mark L. Heiman
    Diabetes 2001 Apr; 50 (4): 707-709. https://doi.org/10.2337/diabetes.50.4.707
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    Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol
    Edmond A. Ryan, Jonathan R.T. Lakey, Ray V. Rajotte, Gregory S. Korbutt, Tatsuya Kin, Sharleen Imes, Alex Rabinovitch, John F. Elliott, David Bigam, Norman M. Kneteman, Garth L. Warnock, Ingrid Larsen and A.M. James Shapiro
    Diabetes 2001 Apr; 50 (4): 710-719. https://doi.org/10.2337/diabetes.50.4.710
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Metabolism and Signal Transduction

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    Control of Glycogen Synthesis by Glucose, Glycogen, and Insulin in Cultured Human Muscle Cells
    Reza Halse, Sylvie M. Bonavaud, Jane L. Armstrong, James G. McCormack and Stephen J. Yeaman
    Diabetes 2001 Apr; 50 (4): 720-726. https://doi.org/10.2337/diabetes.50.4.720
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    In Normal Men, Free Fatty Acids Reduce Peripheral but Not Splanchnic Glucose Uptake
    Vincent Rigalleau, Christophe Binnert, Kaori Minehira, Nathalie Stefanoni, Phillippe Schneiter, Emmanuel Henchoz, Oscar Matzinger, Christine Cayeux, Eric Jéquier and Luc Tappy
    Diabetes 2001 Apr; 50 (4): 727-732. https://doi.org/10.2337/diabetes.50.4.727
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    Cerulenin Mimics Effects of Leptin on Metabolic Rate, Food Intake, and Body Weight Independent of the Melanocortin System, but Unlike Leptin, Cerulenin Fails to Block Neuroendocrine Effects of Fasting
    Hideo Makimura, Tooru M. Mizuno, Xue-Jun Yang, Jeff Silverstein, Joe Beasley and Charles V. Mobbs
    Diabetes 2001 Apr; 50 (4): 733-739. https://doi.org/10.2337/diabetes.50.4.733
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    Rat Small Intestine Is an Insulin-Sensitive Gluconeogenic Organ
    Martine Croset, Fabienne Rajas, Carine Zitoun, Jean-Marc Hurot, Sandrine Montano and Gilles Mithieux
    Diabetes 2001 Apr; 50 (4): 740-746. https://doi.org/10.2337/diabetes.50.4.740
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    Assessment of Postabsorptive Renal Glucose Metabolism in Humans With Multiple Glucose Tracers
    Niels Moller, Robert A. Rizza, G. Charles Ford and K. Sreekumaran Nair
    Diabetes 2001 Apr; 50 (4): 747-751. https://doi.org/10.2337/diabetes.50.4.747
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Immunology and Transplantation

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    Autoantibody Response to CD38 in Caucasian Patients With Type 1 and Type 2 DiabetesImmunological and Genetic Characterization
    Roberto Mallone, Erika Ortolan, Germano Baj, Ada Funaro, Sara Giunti, Emma Lillaz, Franca Saccucci, Maurizio Cassader, Paolo Cavallo-Perin and Fabio Malavasi
    Diabetes 2001 Apr; 50 (4): 752-762. https://doi.org/10.2337/diabetes.50.4.752
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    Development and Function of Diabetogenic T-cells in B-cell–Deficient Nonobese Diabetic Mice
    Priscilla P.L. Chiu, David V. Serreze and Jayne S. Danska
    Diabetes 2001 Apr; 50 (4): 763-770. https://doi.org/10.2337/diabetes.50.4.763
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    Mucosal Antigen Primes Diabetogenic Cytotoxic T-Lymphocytes Regardless of Dose or Delivery Route
    Arno Hänninen, Andrea Braakhuis, William R. Heath and Leonard C. Harrison
    Diabetes 2001 Apr; 50 (4): 771-775. https://doi.org/10.2337/diabetes.50.4.771
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Islet Studies

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    Glucagon-Like Peptide 1 Increases Secretory Burst Mass of Pulsatile Insulin Secretion in Patients With Type 2 Diabetes and Impaired Glucose Tolerance
    Robert Ritzel, Miriam Schulte, Niels Pørksen, Markus S. Nauck, Jens J. Holst, Claus Juhl, Winfried März, Ole Schmitz, Wolff H. Schmiegel and Michael A. Nauck
    Diabetes 2001 Apr; 50 (4): 776-784. https://doi.org/10.2337/diabetes.50.4.776
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    Glucagon-Like Peptide 1 Induces Differentiation of Islet Duodenal Homeobox-1–Positive Pancreatic Ductal Cells Into Insulin-Secreting Cells
    Hongxiang Hui, Chris Wright and Riccardo Perfetti
    Diabetes 2001 Apr; 50 (4): 785-796. https://doi.org/10.2337/diabetes.50.4.785
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    The Novel Imidazoline Compound BL11282 Potentiates Glucose-Induced Insulin Secretion in Pancreatic β-Cells in the Absence of Modulation of KATP Channel Activity
    Alexander M. Efanov, Sergei V. Zaitsev, Hans-Juergen Mest, Achim Raap, Ioulia B. Appelskog, Olof Larsson, Per-Olof Berggren and Suad Efendic
    Diabetes 2001 Apr; 50 (4): 797-802. https://doi.org/10.2337/diabetes.50.4.797
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    Uncoupling Protein 2: A Possible Link Between Fatty Acid Excess and Impaired Glucose-Induced Insulin Secretion?
    Nathalie Lameloise, Patrick Muzzin, Marc Prentki and Françoise Assimacopoulos-Jeannet
    Diabetes 2001 Apr; 50 (4): 803-809. https://doi.org/10.2337/diabetes.50.4.803
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Pathophysiology

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    Effects of Free Fatty Acids on Gluconeogenesis and Autoregulation of Glucose Production in Type 2 Diabetes
    Guenther Boden, Xinhua Chen, Edwin Capulong and Maria Mozzoli
    Diabetes 2001 Apr; 50 (4): 810-816. https://doi.org/10.2337/diabetes.50.4.810
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    Skeletal Muscle Lipid Content and Oxidative Enzyme Activity in Relation to Muscle Fiber Type in Type 2 Diabetes and Obesity
    Jing He, Simon Watkins and David E. Kelley
    Diabetes 2001 Apr; 50 (4): 817-823. https://doi.org/10.2337/diabetes.50.4.817
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    A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo
    Vara Prasad Manchem, Ira D. Goldfine, Ronald A. Kohanski, Cristina P. Cristobal, Robert T. Lum, Steven R. Schow, Songyuan Shi, Wayne R. Spevak, Edgardo Laborde, Deborah K. Toavs, Hugo O. Villar, Michael M. Wick and Michael R. Kozlowski
    Diabetes 2001 Apr; 50 (4): 824-830. https://doi.org/10.2337/diabetes.50.4.824
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    The Q Allele Variant (GLN121) of Membrane Glycoprotein PC-1 Interacts With the Insulin Receptor and Inhibits Insulin Signaling More Effectively Than the Common K Allele Variant (LYS121)
    Benedetta V. Costanzo, Vincenzo Trischitta, Rosa Di Paola, Daniela Spampinato, Antonio Pizzuti, Riccardo Vigneri and Lucia Frittitta
    Diabetes 2001 Apr; 50 (4): 831-836. https://doi.org/10.2337/diabetes.50.4.831
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Complications

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    Increased QTc Dispersion Is Related to Blunted Circadian Blood Pressure Variation in Normoalbuminuric Type 1 Diabetic Patients
    Per Løgstrup Poulsen, Eva Ebbehøj, Hanne Arildsen, Søren Tang Knudsen, Klaus Würgler Hansen, Henning Mølgaard and Carl Erik Mogensen
    Diabetes 2001 Apr; 50 (4): 837-842. https://doi.org/10.2337/diabetes.50.4.837
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    Effect of 3 Years of Antihypertensive Therapy on Renal Structure in Type 1 Diabetic Patients With AlbuminuriaThe European Study for the Prevention of Renal Disease in Type 1 Diabetes (ESPRIT)
    The European Study for the Prevention of Renal Disease in Type 1 Diabetes ESPRIT Study Group
    Diabetes 2001 Apr; 50 (4): 843-850. https://doi.org/10.2337/diabetes.50.4.843
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    Diabetes Accelerates Smooth Muscle Accumulation in Lesions of AtherosclerosisLack of Direct Growth-Promoting Effects of High Glucose Levels
    Lucy A. Suzuki, Martin Poot, Ross G. Gerrity and Karin E. Bornfeldt
    Diabetes 2001 Apr; 50 (4): 851-860. https://doi.org/10.2337/diabetes.50.4.851
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    Familial Aggregation of Coronary Artery Calcium in Families With Type 2 Diabetes
    Lynne E. Wagenknecht, Donald W. Bowden, J. Jeffrey Carr, Carl D. Langefeld, Barry I. Freedman and Stephen S. Rich
    Diabetes 2001 Apr; 50 (4): 861-866. https://doi.org/10.2337/diabetes.50.4.861
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    Angiotensin II Induces Expression of the Tie2 Receptor Ligand, Angiopoietin-2, in Bovine Retinal Endothelial Cells
    Atsushi Otani, Hitoshi Takagi, Hideyasu Oh, Shinji Koyama and Yoshihito Honda
    Diabetes 2001 Apr; 50 (4): 867-875. https://doi.org/10.2337/diabetes.50.4.867
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Genetics

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    Pro12Ala Polymorphism in the Peroxisome Proliferator–Activated Receptor-γ2 Gene Is Associated With Increased Antilipolytic Insulin Sensitivity
    Michael Stumvoll, Hans Günther Wahl, Klaus Löblein, Regine Becker, Fausto Machicao, Stephan Jacob and Hans Häring
    Diabetes 2001 Apr; 50 (4): 876-881. https://doi.org/10.2337/diabetes.50.4.876
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Brief Genetics Report

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    The Gly972Arg Polymorphism in the Insulin Receptor Substrate-1 Gene Contributes to the Variation in insulin Secretion in Normal Glucose-Tolerant Humans
    Michael Stumvoll, Andreas Fritsche, Annette Volk, Norbert Stefan, Alexander Madaus, Elke Maerker, Anna Teigeler, Matthias Koch, Fausto Machicao and Hans Häring
    Diabetes 2001 Apr; 50 (4): 882-885. https://doi.org/10.2337/diabetes.50.4.882
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    The Peroxisome Poliferator–Activated Receptor-γ2 Pro12Ala VariantAssociation With Type 2 Diabetes and Trait Differences
    Julie A. Douglas, Michael R. Erdos, Richard M. Watanabe, Andi Braun, Cristy L. Johnston, Paul Oeth, Karen L. Mohlke, Timo T. Valle, Christian Ehnholm, Thomas A. Buchanan, Richard N. Bergman, Francis S. Collins, Michael Boehnke and Jaakko Tuomilehto
    Diabetes 2001 Apr; 50 (4): 886-890. https://doi.org/10.2337/diabetes.50.4.886
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    The Pro12→Ala Substitution in PPAR-γ Is Associated With Resistance to Development of Diabetes in the General PopulationPossible Involvement in Impairment of Insulin Secretion in Individuals With Type 2 Diabetes
    Hiroyuki Mori, Hiroshi Ikegami, Yoshihiko Kawaguchi, Susumu Seino, Norihide Yokoi, Jun Takeda, Ituro Inoue, Yutaka Seino, Koichiro Yasuda, Toshiaki Hanafusa, Kazuya Yamagata, Takuya Awata, Takashi Kadowaki, Kazuo Hara, Nobuhiro Yamada, Takanari Gotoda, Naoko Iwasaki, Yasuhiko Iwamoto, Tokio Sanke, Kishio Nanjo, Yoshitomo Oka, Akira Matsutani, Eiichi Maeda and Masato Kasuga
    Diabetes 2001 Apr; 50 (4): 891-894. https://doi.org/10.2337/diabetes.50.4.891
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    Differential Splicing of the IA-2 mRNA in Pancreas and Lymphoid Organs as a Permissive Genetic Mechanism for Autoimmunity Against the IA-2 Type 1 Diabetes Autoantigen
    Juan Diez, Yongsoo Park, Markus Zeller, Douglas Brown, David Garza, Camillo Ricordi, John Hutton, George S. Eisenbarth and Alberto Pugliese
    Diabetes 2001 Apr; 50 (4): 895-900. https://doi.org/10.2337/diabetes.50.4.895
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    A Ser311Cys Mutation in the Human Dopamine Receptor D2 Gene Is Associated With Reduced Energy Expenditure
    P. Antonio Tataranni, Leslie Baier, Chris Jenkinson, Inge Harper, Angelo Del Parigi and Clifton Bogardus
    Diabetes 2001 Apr; 50 (4): 901-904. https://doi.org/10.2337/diabetes.50.4.901
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Letter to the Editor

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    Measurements of Renal Glucose Release
    John E. Gerich
    Diabetes 2001 Apr; 50 (4): 905. https://doi.org/10.2337/diabetes.50.4.905
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In this Issue

April 2001, 50(4)
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  • Rapid Publication
  • Metabolism and Signal Transduction
  • Immunology and Transplantation
  • Islet Studies
  • Pathophysiology
  • Complications
  • Genetics
  • Brief Genetics Report
  • Letter to the Editor
  • Most Read
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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
  • Latent Autoimmune Diabetes in Adults
  • Poverty and Obesity in the U.S.
  • The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion
  • A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels
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