Skip to main content
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care
  • Subscribe
  • Log in
  • My Cart
  • Follow ada on Twitter
  • RSS
  • Visit ada on Facebook
Diabetes

Advanced Search

Main menu

  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care

User menu

  • Subscribe
  • Log in
  • My Cart

Search

  • Advanced search
Diabetes
  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
Islet Studies

Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig

  1. Lise L. Kjems1,
  2. Barbara M. Kirby1,
  3. Elizabeth M. Welsh1,
  4. Johannes D. Veldhuis2,
  5. Marty Straume2,
  6. Susan S. McIntyre1,
  7. Dongchang Yang1,
  8. Pierre Lefèbvre3 and
  9. Peter C. Butler1
  1. 1Diabetes Research Unit and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Scotland
  2. 2Center for Biological Timing and Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Virginia
  3. 3Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, University of Liege, Liege, Belgium
    Diabetes 2001 Sep; 50(9): 2001-2012. https://doi.org/10.2337/diabetes.50.9.2001
    PreviousNext
    • Article
    • Figures & Tables
    • Info & Metrics
    • PDF
    Loading

    Article Information

    vol. 50 no. 9 2001-2012
    DOI 
    https://doi.org/10.2337/diabetes.50.9.2001
    PubMed 
    11522665

    Published By 
    American Diabetes Association
    Print ISSN 
    0012-1797
    Online ISSN 
    1939-327X
    History 
    • Published in print September 1, 2001.

    Copyright & Usage 
    © 2001

    Author Information

    1. Lise L. Kjems1,
    2. Barbara M. Kirby1,
    3. Elizabeth M. Welsh1,
    4. Johannes D. Veldhuis2,
    5. Marty Straume2,
    6. Susan S. McIntyre1,
    7. Dongchang Yang1,
    8. Pierre Lefèbvre3 and
    9. Peter C. Butler1
    1. 1Diabetes Research Unit and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, Scotland
    2. 2Center for Biological Timing and Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Virginia
    3. 3Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, University of Liege, Liege, Belgium
      View Full Text

      Statistics from Altmetric.com

      Article usage

      Article usage: August 2001 to February 2021

      Rendering graph...
      AbstractFullPdf
      Aug 2001272851
      Sep 20014710237
      Oct 2001123511
      Nov 2001102322
      Dec 200153212
      Jan 200291915
      Feb 20027244
      Mar 20025185
      Apr 20027205
      May 20024258
      Jun 20025297
      Jul 20022202
      Aug 20023103
      Sep 200231825
      Oct 20021159
      Nov 200252113
      Dec 20021104
      Jan 20035910
      Feb 200331214
      Mar 200332016
      Apr 200382016
      May 2003143414
      Jun 2003242614
      Jul 2003203522
      Aug 2003232712
      Sep 2003202612
      Oct 2003153510
      Nov 2003203112
      Dec 2003253111
      Jan 2004181710
      Feb 2004224321
      Mar 2004134123
      Apr 2004114920
      May 200417487
      Jun 2004185422
      Jul 2004145729
      Aug 2004337217
      Sep 2004217613
      Oct 2004169521
      Nov 200417959
      Dec 2004226915
      Jan 200525647
      Feb 200519588
      Mar 2005207610
      Apr 200593011
      May 2005153113
      Jun 200583110
      Jul 200514367
      Aug 2005153613
      Sep 2005133511
      Oct 200519326
      Nov 2005242910
      Dec 2005143112
      Jan 2006226613
      Feb 2006164918
      Mar 200693918
      Apr 2006163211
      May 2006142517
      Jun 200614167
      Jul 200611195
      Aug 2006102212
      Sep 20069239
      Oct 20069379
      Nov 2006113318
      Dec 20068148
      Jan 20079219
      Feb 200741310
      Mar 20078169
      Apr 200752717
      May 200761513
      Jun 2007191720
      Jul 20076116
      Aug 20073911
      Sep 2007898
      Oct 20078116
      Nov 200713168
      Dec 2007397
      Jan 200851610
      Feb 2008955
      Mar 200821169
      Apr 200871113
      May 200810911
      Jun 200812237
      Jul 20081396
      Aug 2008161515
      Sep 200861218
      Oct 2008121413
      Nov 200811157
      Dec 20089158
      Jan 20097196
      Feb 20098169
      Mar 20091387
      Apr 20095158
      May 2009398
      Jun 20094125
      Jul 200914813
      Aug 2009894
      Sep 20091563
      Oct 20091131
      Nov 20091255
      Dec 2009866
      Jan 2010161211
      Feb 2010466
      Mar 201018138
      Apr 201010138
      May 201010109
      Jun 201010107
      Jul 2010111014
      Aug 2010553
      Sep 20101074
      Oct 2010873
      Nov 2010131611
      Dec 20109126
      Jan 20118193
      Feb 20111987
      Mar 201115115
      Apr 201116189
      May 20119219
      Jun 2011192012
      Jul 201111127
      Aug 201122159
      Sep 20112176
      Oct 2011301111
      Nov 2011131312
      Dec 2011866
      Jan 2012141013
      Feb 2012121522
      Mar 20121884
      Apr 201217129
      May 20121598
      Jun 2012191115
      Jul 201215118
      Aug 20122076
      Sep 201218812
      Oct 201220107
      Nov 2012191711
      Dec 2012221411
      Jan 201313208
      Feb 201321367
      Mar 2013181410
      Apr 201313811
      May 20131388
      Jun 20131635
      Jul 2013859
      Aug 20131532
      Sep 2013354
      Oct 20137125
      Nov 201310102
      Dec 20131573
      Jan 20146106
      Feb 2014682
      Mar 201472510
      Apr 20145356
      May 20147265
      Jun 20141167
      Jul 20143760
      Aug 20141819
      Sep 2014932
      Oct 2014833
      Nov 20141176
      Dec 20141034
      Jan 2015594
      Feb 2015862
      Mar 20151153
      Apr 20151765
      May 20159124
      Jun 201531312
      Jul 20151083
      Aug 2015220
      Sep 20154272
      Oct 20151382
      Nov 201512511
      Dec 20151555
      Jan 201614116
      Feb 2016954
      Mar 201662149
      Apr 20165410
      May 2016113612
      Jun 201622816
      Jul 20164289
      Aug 20166295
      Sep 20169125
      Oct 20168259
      Nov 201662010
      Dec 20160162
      Jan 20171191
      Feb 20170263
      Mar 20174266
      Apr 201742612
      May 20177148
      Jun 20171287
      Jul 20174168
      Aug 20173293
      Sep 20172295
      Oct 20173257
      Nov 20170192
      Dec 20172187
      Jan 20181102
      Feb 20180141
      Mar 20180315
      Apr 20180235
      May 201822194
      Jun 20180191
      Jul 20182221
      Aug 20181183
      Sep 2018214917
      Oct 201811985
      Nov 201802355
      Dec 201802003
      Jan 201921438
      Feb 201931175
      Mar 20191546
      Apr 201912813
      May 20192388
      Jun 20192188
      Jul 20192166
      Aug 20191456
      Sep 201912846
      Oct 20191357
      Nov 20193259
      Dec 20191218
      Jan 20201311
      Feb 20202228
      Mar 20200143
      Apr 20201124
      May 2020084
      Jun 2020121
      Jul 2020242
      Aug 20201146
      Sep 20204236
      Oct 20201224
      Nov 20206307
      Dec 20204508
      Jan 202113115
      Feb 20210343

      PreviousNext
      Back to top

      In this Issue

      September 2001, 50(9)
      • Table of Contents
      • Index by Author
      Sign up to receive current issue alerts
      View Selected Citations (0)
      Print
      Download PDF
      Article Alerts
      Sign In to Email Alerts with your Email Address
      Email Article

      Thank you for your interest in spreading the word about Diabetes.

      NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

      Enter multiple addresses on separate lines or separate them with commas.
      Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig
      (Your Name) has forwarded a page to you from Diabetes
      (Your Name) thought you would like to see this page from the Diabetes web site.
      CAPTCHA
      This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
      Citation Tools
      Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig
      Lise L. Kjems, Barbara M. Kirby, Elizabeth M. Welsh, Johannes D. Veldhuis, Marty Straume, Susan S. McIntyre, Dongchang Yang, Pierre Lefèbvre, Peter C. Butler
      Diabetes Sep 2001, 50 (9) 2001-2012; DOI: 10.2337/diabetes.50.9.2001

      Citation Manager Formats

      • BibTeX
      • Bookends
      • EasyBib
      • EndNote (tagged)
      • EndNote 8 (xml)
      • Medlars
      • Mendeley
      • Papers
      • RefWorks Tagged
      • Ref Manager
      • RIS
      • Zotero
      Add to Selected Citations
      Share

      Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig
      Lise L. Kjems, Barbara M. Kirby, Elizabeth M. Welsh, Johannes D. Veldhuis, Marty Straume, Susan S. McIntyre, Dongchang Yang, Pierre Lefèbvre, Peter C. Butler
      Diabetes Sep 2001, 50 (9) 2001-2012; DOI: 10.2337/diabetes.50.9.2001
      del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
      • Tweet Widget
      • Facebook Like
      • Google Plus One

      Jump to section

      • Article
        • Abstract
        • RESEARCH DESIGN AND METHODS
        • RESULTS
        • DISCUSSION
        • Acknowledgments
        • Footnotes
        • REFERENCES
      • Figures & Tables
      • Info & Metrics
      • PDF

      Related Articles

      Cited By...

      More in this TOC Section

      • Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia
      • Acyl-Ghrelin Influences Pancreatic β-Cell Function by Interference with KATP Channels
      • Pancreatic β-Cell–Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion
      Show more Islet Studies

      Similar Articles

      Navigate

      • Current Issue
      • Online Ahead of Print
      • Scientific Sessions Abstracts
      • Collections
      • Archives
      • Submit
      • Subscribe
      • Email Alerts
      • RSS Feeds

      More Information

      • About the Journal
      • Instructions for Authors
      • Journal Policies
      • Reprints and Permissions
      • Advertising
      • Privacy Policy: ADA Journals
      • Copyright Notice/Public Access Policy
      • Contact Us

      Other ADA Resources

      • Diabetes Care
      • Clinical Diabetes
      • Diabetes Spectrum
      • Scientific Sessions Abstracts
      • Standards of Medical Care in Diabetes
      • BMJ Open - Diabetes Research & Care
      • Professional Books
      • Diabetes Forecast

       

      • DiabetesJournals.org
      • Diabetes Core Update
      • ADA's DiabetesPro
      • ADA Member Directory
      • Diabetes.org

      © 2021 by the American Diabetes Association. Diabetes Print ISSN: 0012-1797, Online ISSN: 1939-327X.